Parcourir par sujet "bilirubin blood level"
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A chronic alcoholic man with high fever, neck rigidity and loss of consciousness: Remember the Austrian syndrome a commonly unrecognised invasive pneumococcus triad
(2018)Austrian syndrome is a rare medical condition characterised by the triad of pneumonia, meningitis and endocarditis due to Streptococcus pneumoniae. Native aortic valve insufficiency is the most common cause of cardiac ... -
Decreased serum DNase1-activity in patients with autoimmune liver diseases
(2017)Deoxyribonuclease1 (DNase1) is involved in chromatin degradation of apoptotic cells. Its deficiency results in accumulation of self-DNA, which in turn may induce inflammation and autoimmunity. We assessed for the first ... -
Effects of Age and Sex of Response to Ursodeoxycholic Acid and Transplant-free Survival in Patients With Primary Biliary Cholangitis
(2019)Background & Aims: Primary biliary cholangitis (PBC) predominantly affects middle-aged women; there are few data on disease phenotypes and outcomes of PBC in men and younger patients. We investigated whether differences ... -
Evaluating Alternative Ramucirumab Doses as a Single Agent or with Paclitaxel in Second-Line Treatment of Locally Advanced or Metastatic Gastric/Gastroesophageal Junction Adenocarcinoma: Results from Two Randomized, Open-Label, Phase II Studies
(2022)Studies JVDB and JVCZ examined alternative ramucirumab dosing regimens as monotherapy or combined with paclitaxel, respectively, in patients with advanced/metastatic gastric/gastroesophageal junction (GEJ) adenocarcinoma. ... -
Factors Associated With Progression and Outcomes of Early Stage Primary Biliary Cholangitis
(2020)Background & Aims: Patients usually receive a diagnosis of primary biliary cholangitis (PBC) at an early stage, based on biochemical analyses. We investigated the proportion of patients who progress to moderate or advanced ... -
A Middle-Aged Woman With Viral ARDS and Acute Establishment of Shock on Invasive Mechanical Ventilation
(2021)[No abstract available] -
Non-alcoholic steatohepatitis or autoimmune hepatitis? Sometimes a closer look under the surface is needed
(2020)Non-alcoholic fatty liver disease (NAFLD) is nowadays the most common liver disease worldwide. Autoimmune hepatitis (AIH) is a relatively rare disease of the liver characterised by female predominance, circulating ... -
Promyelocytic leukemia antigen expression: A histological marker for primary biliary cholangitis diagnosis?
(2021)Distinguishing primary biliary cholangitis (PBC) from other cholestatic diseases at the histological level could be assisted by new methods, such as immunohistochemical staining of specific antigens. We evaluated whether ... -
Prospective evaluation of PBC-specific health-related quality of life questionnaires in patients with primary sclerosing cholangitis
(2015)Background & Aims: Primary biliary cirrhosis and Primary sclerosing cholangitis are autoimmune cholestatic liver diseases sharing a lot in common, including a significant impairment of patients' health-related quality of ... -
Simulating real-life exposures to uncover possible risks to human health: A proposed consensus for a novel methodological approach
(2017)In real life, consumers are exposed to complex mixtures of chemicals via food, water and commercial products consumption. Since risk assessment usually focuses on individual compounds, the current regulatory approach doesn't ... -
Six months exposure to a real life mixture of 13 chemicals' below individual NOAELs induced non monotonic sex-dependent biochemical and redox status changes in rats
(2018)This study assessed the potential adverse health effects of long-term low-dose exposure to chemical mixtures simulating complex real-life human exposures. Four groups of Sprague Dawley rats were administered mixtures ... -
Support of precision medicine through risk-stratification in autoimmune liver diseases – histology, scoring systems, and non-invasive markers
(2018)Autoimmune liver diseases (AILDs) are complex conditions, which arise from the interaction between a genetic susceptibility and unknown environmental triggers. They represent a relevant cause of liver failure and liver ... -
Α 57-Year-Old Woman With ARDS, Cachexia, and a 2-Month Fever
(2019)Case Presentation: A 57-year-old homemaker and rural inhabitant of Central Greece (ex-smoker, 25 pack-years), was admitted to the ICU because of acute hypoxemic respiratory failure with diffuse bilateral alveolar infiltrates. ...