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Πλοήγηση ανά Θέμα "TYROSINE KINASE"

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    • The angiogenic pathway 'vascular endothelial growth factor/flk-I (KDR)-receptor' in rheumatoid arthritis and osteoarthritis 

      Giatromanolaki, A.; Sivridis, E.; Atanassou, N.; Zois, E.; Thorpe, P. E.; Brekken, R. A.; Gatter, K. C.; Harris, A. L.; Koukourakis, I. M.; Koukourakis, M. I. (2001)
      Active angiogenesis, together with an up-regulation of angiogenic factors, is evident in the synovium of both rheumatoid arthritis (RA) and osteoarthritis (OA). The present study assessed, by immunohistochemistry, the ...

    • Catch the kinase conformer 

      McInnes, C.; Mezna, M.; Kontopidis, G. (2006)
      Protein kinases exist in inactive and active states, but little attention has been paid to which state is or should be the target in drug discovery efforts. In this issue of Chemistry & Biology, Okram et al. [1] tackle ...

    • Hypoxia Inducible Factor-1alpha and Vascular Endothelial Growth Factor in Biopsies of Small Cell Lung Carcinoma 

      Ioannou, M.; Papamichali, R.; Kouvaras, E.; Mylonis, I.; Vageli, D.; Kerenidou, T.; Barbanis, S.; Daponte, A.; Simos, G.; Gourgoulianis, K.; Koukoulis, G. K. (2009)
      Neoangiogenesis has been documented in small cell lung carcinoma (SCLC). In addition, antiangiogenic therapies are being tested in clinical trials that involve SCLC. However, study of the underlying mechanisms has been ...