Parcourir par sujet "Sequence Analysis"
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JUCHMME: A Java Utility for Class Hidden Markov Models and Extensions for biological sequence analysis
(2019)JUCHMME is an open-source software package designed to fit arbitrary custom Hidden Markov Models (HMMs) with a discrete alphabet of symbols. We incorporate a large collection of standard algorithms for HMMs as well as a ... -
Semi-supervised learning of hidden markov models for biological sequence analysis
(2019)Motivation: Hidden Markov Models (HMMs) are probabilistic models widely used in applications in computational sequence analysis. HMMs are basically unsupervised models. However, in the most important applications, they are ... -
Sensitivity and applications of the PCR Single-Strand Conformation Polymorphism method
(2021)PCR Single-Strand Conformation Polymorphism is a method used to identify and detect mutations and is now well known for its many applications on living beings. This paper will discuss the experimental details, limitations ... -
A unique hydrophobic cluster near the active site contributes to differences in borrelidin inhibition, among threonyl-tRNA synthetases
(2005)Borrelidin, a compound with anti-microbial and anti-angiogenic properties, is a known inhibitor of bacterial and eukaryal threonyl-tRNA synthetase (ThrRS). The inhibition mechanism of borrelidin is not well understood. ...