Πλοήγηση ανά Θέμα "SYSTEMIC-LUPUS-ERYTHEMATOSUS"
Αποτελέσματα 1-20 από 22
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Autoimmunity and Environment: Am I at risk?
(2012)The complex interplay between environmental factors and genetic susceptibility plays an essential role in disease pathogenesis. This is especially true for autoimmunity, where clinical reports, genomic and epidemiological ... -
Bone marrow findings in patients with autoimmune liver diseases
(2008)Background and Aims: We have recently reported quantitative and qualitative differences of the bone marrow (BM) hematopoietic progenitor cells in autoimmune hepatitis type-1 (AIH-1) and primary biliary cirrhosis (PBC). In ... -
Fc gamma receptor polymorphisms and their association with periodontal disease: a meta-analysis
(2010)Aim: A systematic review and a meta-analysis were conducted in order to investigate the potential association of Fc gamma receptor (Fc gamma R) polymorphisms with susceptibility to aggressive and chronic periodontal disease. ... -
Helicobacter pylori and autoimmune disease: Cause or bystander
(2014)Helicobacter pylori (H. pylori) is the main cause of chronic gastritis and a major risk factor for gastric cancer. This pathogen has also been considered a potential trigger of gastric autoimmunity, and in particular of ... -
IgA anti-b2GPI antibodies in patients with autoimmune liver diseases
(2008)Introduction Recently, we reported a high prevalence of immunoglobulin G and/or immunoglobulin M anticardiolipin antibodies (aCL) in patients with autoimmune liver diseases, namely, autoimmune hepatitis (AIH), primary ... -
The impact of frequently encountered cardiovascular risk factors on sexual dysfunction in rheumatic disorders
(2013)Traditional cardiovascular risk factors have been acknowledged as major contributors to sexual dysfunction in the general population. The purpose of this study was to explore their impact on sexual function in rheumatologic ... -
Impaired degradation and aberrant phagocytosis of necrotic cell debris in the peripheral blood of patients with primary Sjogren's syndrome
(2015)Aberrant removal of necrotic debris is considered a feature with inflammatory consequences in SLE. Herein, primary Sjogren's syndrome (SS) patients were investigated for the first time for the capacity of their sera to ... -
Infectome: A platform to trace infectious triggers of autoimmunity
(2013)The "exposome" is a term recently used to describe all environmental factors, both exogenous and endogenous, which we are exposed to in a lifetime. It represents an important tool in the study of autoimmunity, complementing ... -
Infectomics and autoinfectomics: a tool to study infectious-induced autoimmunity
(2015)The exposome represents all exogenous and endogenous environmental exposures that begin at preconception and carry on throughout life, while the microbiome reflects the microbial component of the exposome. We recently ... -
Interleukin-15 (IL-15) and Anti-C1q Antibodies as Serum Biomarkers for Ectopic Pregnancy and Missed Abortion
(2013)Given the present lack of clinically useful tests for the accurate diagnosis of ectopic pregnancy (EP), there is a need to select out those immunological factors measured in the maternal serum, as potential biomarkers. Our ... -
Morbidity, Mortality, and Organ Damage in Patients with Antiphospholipid Syndrome
(2012)Objective. To describe morbidity, organ damage, mortality, and cause of death in patients with antiphospholipid syndrome (APS). Methods. Descriptive analysis of 135 patients. Patients were clustered according to initial ... -
Polymorphisms of the CD24 Gene Are Associated with Risk of Multiple Sclerosis: A Meta-Analysis
(2015)CD24 is a cell-surface protein mainly expressed in cells of the immune and central nervous system (CNS), cells that play a critical role in the development of multiple sclerosis (MS). In the current study, we investigated ... -
Predictive role of cytokine gene polymorphisms for the development of femoral head osteonecrosis
(2012)Introduction: Osteonecrosis (ON) is a multifactorial disease that leads to hip destruction. Lately, much focus has been at femoral head preservation with nonsurgical methods. In this study we examined the polymorphisms of ... -
Presence of high avidity anticardiolipin antibodies in patients with autoimmune cholestatic liver diseases
(2006)We studied the prevalence and clinical significance of anticardiolipin antibodies (aCL) in primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) as similar data are missing. Ninety-nine PBC patients, 41 ... -
The prevalence of rheumatic diseases in central Greece: a population survey
(2010)Background: Rheumatic diseases are a major health and financial burden for societies. The prevalence of rheumatic diseases may change over time, and therefore, we sought to estimate the prevalence of rheumatic diseases in ... -
Retinal vasculitis in rheumatic diseases: an unseen burden
(2013)Retinal vascular inflammation, a potentially blinding condition (herein: retinal vasculitis (RV)) is commonly associated with a heterogeneous group of diseases characterized by systemic inflammatory cell infiltration and/or ... -
Sex Differences Associated with Primary Biliary Cirrhosis
(2012)Primary biliary cirrhosis (PBC) is a cholestatic liver disease of autoimmune origin, characterised by the destruction of small intrahepatic bile ducts. The disease has an unpredictable clinical course but may progress to ... -
Stress, coping strategies and social support in patients with primary Sjogren's syndrome prior to disease onset: a retrospective case-control study
(2009)Objectives: Previous evidence suggests the role of psychological stress in triggering the onset of auto-immunity. We aimed to investigate whether stress following major and minor life events could precede the onset of ... -
T-Cell zeta chain expression, phosphorylation and degradation and their role in T-cell signal transduction and immune response regulation in health and disease
(2006)T-cell zeta chain expression, phosphorylation and degradation and their role in T-cell signal transduction and immune response regulation in health and disease. Zeta chain is a stable constituent of the antigen specific ... -
Tracing environmental markers of autoimmunity: introducing the infectome
(2013)We recently introduced the concept of the infectome as a means of studying all infectious factors which contribute to the development of autoimmune disease. It forms the infectious part of the exposome, which collates all ...