Browsing by Subject "PARKINSONS-DISEASE"
Now showing items 1-18 of 18
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Association of methylenetetrahydrofolate reductase (MTHFR) polymorphisms with genetic susceptibility to gastric cancer: a meta-analysis
(2006)To clarify the influence of MTHFR C677T and A1298C polymorphisms on gastric cancer (GC), a meta-analysis of eight case-control studies (1,584/2,785 cases/controls) was carried out. Overall, there was moderate heterogeneity ... -
Attractor Divergence as a Metric for Assessing Walking Balance
(2010)Individuals with Parkinson's disease and the aged have a high prevalence of falls. Since an increase in the number of falls is associated with physical and psychological harm, it is prudent that biomechanical metrics be ... -
Brain-derived neurotrophic factor gene polymorphisms and schizophrenia: a meta-analysis
(2007)Objectives: To evaluate whether the G196A and C270T polymorphisms of the brain-derived neurotrophic factor gene are associated with increased risk of schizophrenia. Methods: A meta-analysis of nine genetic association ... -
C677T and A1298C methylenetetrahydrofolate reductase gene polymorphisms in schizophrenia, bipolar disorder and depression: a meta-analysis of genetic association studies
(2006)A meta-analysis of the previous studies of allelic association between schizophrenia, bipolar disorder and depression with the C677T and A1298C polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) gene was ... -
Current trends in the management of uremic restless legs syndrome: A systematic review on aspects related to quality of life, cardiovascular mortality and survival
(2015)Restless legs syndrome (RLS) affects almost one out of three end-stage renal disease patients. This review assesses the current treatment options for uremic RLS and the potential benefits of those treatments on quality of ... -
Investigation of Unmedicated Early Onset Restless Legs Syndrome by Voxel-Based Morphometry, T2 Relaxometry, and Functional MR Imaging during the Night-Time Hours
(2012)BACKGROUND AND PURPOSE: The pathophysiology of eRLS has not yet been elucidated. The purpose of the study was to assess, in patients with eRLS, the volume, iron content, and activation of the brain during night-time episodes ... -
Is 472G/A catechol-O-methyl-transferase gene polymorphism related to panic disorder?
(2007)Objectives Case-control studies relating 472G/A catechol-O-methyl-transferase polymorphism with the risk of developing panic disorder showed inconclusive or contradictory results. To shed some light on these results a ... -
Methylenetetrahydrofolate reductase gene and susceptibility to breast cancer: a meta-analysis
(2006)The methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms have been linked to the risk of developing breast cancer. A meta-analysis of 18 case-control studies investigating the association between the C677T and ... -
Methylenetetrahydrofolate reductase gene polymorphism as a risk factor for diabetic nephropathy: a meta-analysis
(2007)Investigations into the association between diabetic nephropathy (DN) and MTHFR C677T gene polymorphism in several case-control studies has yielded contradictory results. To shed light on these inconclusive findings, a ... -
Motor signs predict poor outcomes in Alzheimer disease
(2005)Objective: To examine whether the presence of motor signs has predictive value for important outcomes in Alzheimer disease (AD). Methods: A total of 533 patients with AD at early stages (mean Folstein Mini-Mental State ... -
Mutated alpha-synuclein gene in two Greek kindreds with familial PD: Incomplete penetrance?
(1999)The G209A mutation in the alpha-synuclein gene has been associated with autosomal dominant PD (ADPD) in a family from Contursi, Italy, and three apparently unrelated Greek families. Several groups around the world failed ... -
Protein misfolding in neurodegenerative diseases
(2004)A common pathogenic mechanism shared by diverse neurodegenerative disorders, like Alzheimer's disease, Parkinson's disease, Huntington's disease and transmissible spongiform encephalopathies, may be altered protein homeostasis ... -
The role of MTHFR gene in multiple myeloma
(2008)Case-control studies investigating associations between multiple myeloma (MM) and the C677T and A1298C polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) have provided controversial results. In an attempt to ... -
Sleep-disordered breathing and blood pressure in children - A meta-analysis
(2007)Objectives: To estimate the risk of elevated blood pressure (BP) in children with obstructive sleep-disordered breathing (SDB) and to explore heterogeneity among published studies. Data Source: PubMed database. Study ... -
Stable expression of a neuronal dopaminergic progenitor phenotype in cell lines derived from human amniotic fluid cells
(2006)Cells from human amniotic fluid derived from the fetus are considered a source of multipotent cells. Their properties have not been fully exploited, partially because unlike other embryonic sources such as embryonic stem ... -
Trends in meta-analysis of genetic association studies
(2008)The number of published genetic association studies (GASs) is increasing tremendously due to the availability of mapped single-nucleotide polymorphisms (SNPs) and advances in genotyping technologies. A search in HuGENet ... -
Whole-body vibration and rehabilitation of chronic diseases: A review of the literature
(2012)The objectives of the study were to review the current literature and findings on the effects of whole-body vibration (WBV) as a training method on performance and its ability to aid in the rehabilitation of chronic diseases ...