• Adverse effects of androgen deprivation therapy in patients with prostate cancer: Focus on muscle and bone health 

      Bargiota A., Oeconomou A., Zachos I., Samarinas M., Pisters L.L., Tzortzis V. (2020)
      Androgen deprivation therapy (ADT) is the most effective systemic treatment for prostate cancer and can be succeeded either surgically or pharmaceutically. Both approaches lead to hypogonadism with a large variety of adverse ...
    • Cell environment shapes TDP-43 function with implications in neuronal and muscle disease 

      Šušnjar U., Škrabar N., Brown A.-L., Abbassi Y., Phatnani H., Phatnani H., Fratta P., Kwan J., Sareen D., Broach J.R., Simmons Z., Arcila-Londono X., Lee E.B., Van Deerlin V.M., Shneider N.A., Fraenkel E., Ostrow L.W., Baas F., Berry J.D., Butovsky O., Baloh R.H., Shalem O., Heiman-Patterson T., Stefanis L., Chandran S., Pal S., Smith C., Malaspina A., Hammell M.G., Patsopoulos N.A., Dubnau J., Poss M., Zhang B., Zaitlen N., Hornstein E., Miller T.M., Dardiotis E., Bowser R., Menon V., Harms M., Atassi N., Lange D.J., MacGowan D.J., McMillan C., Aronica E., Harris B., Ravits J., Crary J., Thompson L.M., Raj T., Paganoni S., Adams D.J., Babu S., Drory V., Gotkine M., Broce I., Phillips-Cremins J., Nath A., Finkbeiner S., Cox G.A., Cortese A., Cereda C., Bugiardini E., Cardani R., Meola G., Ripolone M., Moggio M., Romano M., Secrier M., Fratta P., Buratti E., NYGC ALS Consortium (2022)
      TDP-43 (TAR DNA-binding protein 43) aggregation and redistribution are recognised as a hallmark of amyotrophic lateral sclerosis and frontotemporal dementia. As TDP-43 inclusions have recently been described in the muscle ...
    • A clip in the right place: Successful endoscopic submucosal dissection of a cecal tumor exhibiting the muscle-retracting sign 

      Fukuda H., Kowazaki Y., Saito I., Hirooka S., Kurokawa T., Kanzaki N., Manolakis A.C. (2022)
      [No abstract available]
    • Creation and implementation of a European registry for patients with McArdle disease and other muscle glycogenoses (EUROMAC registry) 

      Pinós T., Andreu A.L., Bruno C., Hadjigeorgiou G.M., Haller R.G., Laforêt P., Lucía A., Martín M.A., Martinuzzi A., Navarro C., Oflazer P., Pouget J., Quinlivan R., Sacconi S., Scalco R.S., Toscano A., Vissing J., Vorgerd M., Wakelin A., Martí R., Baruch N., Ortega F.J., San-Millán B., Vieitez I., Vavla M., Musumeci O., Scalco R., Hadjgeorgiou G., Zintzaras E., Zülow E., Haller R., Durmus H., Santalla A., EUROMAC Consortium (2020)
      Background: International patient registries are of particular importance for rare disorders, as they may contribute to overcome the lack of knowledge derived from low number of patients and limited awareness of these ...
    • The effect of Trichinella spiralis on muscular activity of experimentally infected mice 

      Marian I., Ionică A.M., Deak G., Ursache T., Lefkaditis M., Gherman C.M., Mihalca A.D. (2020)
      Nematodes of genus Trichinella are wide-spread zoonotic parasites, able to infect a large variety of vertebrates. Animal hosts are usually regarded as asymptomatic carriers. However, there is little data regarding the ...
    • Flash proton radiotherapy spares normal epithelial and mesenchymal tissues while preserving sarcoma response 

      Velalopoulou A., Karagounis I.V., Cramer G.M., Kim M.M., Skoufos G., Goia D., Hagan S., Verginadis I.I., Shoniyozov K., Chiango J., Cerullo M., Varner K., Yao L., Qin L., Hatzigeorgiou A.G., Minn A.J., Putt M., Lanza M., Assenmacher C.-A., Radaelli E., Huck J., Diffenderfer E., Dong L., Metz J., Koumenis C., Cengel K.A., Maity A., Busch T.M. (2021)
      In studies of electron and proton radiotherapy, ultrahigh dose rates of FLASH radiotherapy appear to produce fewer toxicities than standard dose rates while maintaining local tumor control. FLASHproton radiotherapy (F-PRT) ...
    • Glycogen phosphorylase revisited: Extending the resolution of the R- And T-state structures of the free enzyme and in complex with allosteric activators 

      Leonidas D.D., Zographos S.E., Tsitsanou K.E., Skamnaki V.T., Stravodimos G., Kyriakis E. (2021)
      The crystal structures of free T-state and R-state glycogen phosphorylase (GP) and of R-state GP in complex with the allosteric activators IMP and AMP are reported at improved resolution. GP is a validated pharmaceutical ...
    • Tuberculous pyomyositis: A re-emerging entity of many faces 

      Simopoulou T., Varna A., Dailiana Z., Katsiari C., Alexiou I., Basdekis G., Malizos K.N., Sakkas L.I. (2016)
      Tuberculosis (TB) has become a global concern due to its increasing incidence, particularly in immunocompromised patients, closely following the migratory patterns of populations. TB pyomyositis is a rare extrapulmonary ...