Πλοήγηση ανά Θέμα "LOCALIZATION"
Αποτελέσματα 1-17 από 17
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Association of Syndecan-1 with Angiogenesis-related Markers, Extracellular Matrix Components, and Clinicopathological Features in Colorectal Carcinoma
(2012)Syndecan-1 is a transmembrane heparansulfate proteoglycan, which regulates cell proliferation, migration, angiogenesis, cell-to-cell and cell-to-extracellular matrix adhesion and may influence malignant cell behavior. We ... -
Atypical CRM1-dependent nuclear export signal mediates regulation of hypoxia-inducible factor-1 alpha by MAPK
(2008)Hypoxia-inducible factor 1 (HIF-1) is the key transcriptional activator of hypoxia-inducible genes and an important anti-cancer target. Its regulated subunit, HIF-1 alpha, is controlled by oxygen levels and major signaling ... -
CD10 Is Inversely Associated with Nuclear Factor-Kappa B and Predicts Biochemical Recurrence after Radical Prostatectomy
(2012)Introduction: The cell surface endopeptidase CD10 (neutral endopeptidase) and nuclear factor-kappa B (NF-kappa B) have been independently associated with prostate cancer (PC) progression. We investigated the correlations ... -
Cloning and characterization of an alternatively spliced form of SR protein kinase 1 that interacts specifically with scaffold attachment factor-B
(2001)Serine/arginine protein kinases have been conserved throughout evolution and are thought to play important roles in the regulation of mRNA processing, nuclear import, germline development, polyamine transport, and ion ... -
Distribution of Energy-Momentum in a Schwarzschild-Quintessence Space-Time Geometry
(2013)An analysis of the energy-momentum localization for a four-dimensional Schwarzschild black hole surrounded by dark energy in the form of quintessence is presented in order to provide expressions for the distributions of ... -
Endothelin-3 and PRL levels in the maternal and fetal circulation at delivery
(2007)Objective: The aim of the present cross-sectional study was to test the hypothesis that endothelin-3 (ET-3) is involved in PRL secretion via systemic hormonal interaction during labor. Materials and methods: Fifty healthy ... -
Energy distribution of the Einstein-Klein-Gordon system for a static spherically symmetric space-time in (2+1) dimensions
(2006)We use Moller's energy-momentum complex in order to explicitly compute the energy and momentum density distributions for an exact solution of Einstein's field equations with a negative cosmological constant, minimally ... -
Finite element implementation of gradient plasticity models - Part I: Gradient-dependent yield functions
(1998)Theories with intrinsic or material length scales find applications in the modeling of size-dependent phenomena such as, for example, the localization of plastic flow into shear bands. In gradient-type plasticity theories, ... -
Genetic basis of Parkinson disease
(2010)Over the past few years, considerable progress has been made in understanding the molecular mechanisms of Parkinson disease (PD). Mutations in certain genes are found to cause monogenic forms of the disorder, with autosomal ... -
Microsatellite instability and loss of heterozygosity at the MEN1 locus in lung carcinoid tumors: A novel approach using real-time PCR with melting curve analysis in histopathologic material
(2006)The possible causes and genetic mechanisms of pulmonary carcinoid tumor development are unclear. In this study, we examined genetic alterations at the MEN1 locus in archival material from 15 pulmonary carcinoids. We employed, ... -
Predictive value of telomerase reverse transcriptase expression in patients with high risk superficial bladder cancer treated with adjuvant BCG immunotherapy
(2009)We conducted a prospective study to determine whether expression of telomerase reverse transcriptase (hTERT) is associated with recurrence-free-survival (RFS) or development of invasive disease in patients with high risk ... -
Primary CD30-positive cutaneous T-cell lymphomas and lymphomatoid papulosis frequently express cytotoxic proteins
(2000)Alms: To analyse the relationship between expression of cytotoxic proteins. histopathology and the CD30 status in primary cutaneous T-cell disorders, we investigated the expression of TIA-1, granzyme B and perforin in CD30 ... -
The selective 5-HT6 receptor antagonist Ro 04-6790 attenuates psychotomimetic effects of the NMDA receptor antagonist MK-801
(2008)There are experimental evidences indicating that the non-competitive NMDA receptor antagonist MK-801 impairs cognition and produces a series of schizophrenia-like symptoms in rodents (hypermotility, stereotypies and ataxia). ... -
Stability of long transversely-isotropic elastic cylindrical shells under bending
(2010)The present paper investigates buckling of cylindrical shells of transversely-isotropic elastic material subjected to bending, considering the nonlinear prebuckling ovalized configuration. A large-strain hypoelastic model ... -
A study of size effects and length scales in fracture and fatigue of metals by second gradient modelling
(2012)As the dimensions of structures are scaled down to the micro- and nano-domains, the mechanical behaviour becomes size dependent and thus, we cannot expect the classical elasticity solutions to hold. In particular, recent ... -
Temporal pole proton preoperative magnetic resonance spectroscopy in patients undergoing surgery for mesial temporal sclerosis
(2012)Object. The purpose of this prospective study was to compare the results of proton MR spectroscopy (MRS) in temporal poles in patients with unilateral mesial temporal sclerosis (MTS) with the histopathological findings of ... -
Transport of hypoxia-inducible factor HIF-1 alpha into the nucleus involves importins 4 and 7
(2009)Hypoxia-inducible transcription factor 1 (HIF-1) mediates the cellular response to hypoxia. HIF-1 activity is controlled via the synthesis, degradation or intracellular localization of its alpha subunit. HIF-1 alpha contains ...