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Πλοήγηση ανά Θέμα "HYPOXIA-INDUCIBLE FACTORS"

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    • Cobalt stimulates HIF-1-dependent but inhibits HIF-2-dependent gene expression in liver cancer cells 

      Befani, C.; Mylonis, I.; Gkotinakou, I. M.; Georgoulias, P.; Hu, C. J.; Simos, G.; Liakos, P. (2013)
      Hypoxia-inducible factors (HIFs) are transcriptional regulators that mediate the cellular response to low oxygen. Although HIF-1 is usually considered as the principal mediator of hypoxic adaptation, several tissues and ...

    • Oxygen-dependent secretion of a bioactive hepcidin-GFP chimera 

      Chachami, G.; Lyberopoulou, A.; Kalousi, A.; Paraskeva, E.; Pantopoulos, K.; Simos, G. (2013)
      Hepcidin, a hepatic hormone, regulates serum iron levels by controlling both intestinal iron absorption and iron release from macrophages. Although transcription of hepcidin is controlled by diverse stimuli, it remains ...