Πλοήγηση ανά Θέμα "HIV-1"
Αποτελέσματα 1-5 από 5
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Biophysical characterization of V3-lipopeptide liposomes influencing HIV-1 infectivity
(2007)The V3-loop of the HIV-1 gp120 alters host cell immune function and modulates infectivity. We investigated biophysical parameters of liposome constructs with embedded lipopeptides from the principle neutralizing domain of ... -
Characterization of the interaction between peptides derived from the gp 120/V3 domain of HIV-1 and the amino terminal of the chemokine receptor CCR5 by NMR spectroscopy and light scattering
(2006)We applied static and dynamic light scattering (DLS) to probe the structural and physicochemical determinants of the interaction between the gp120 V3 domain of the human immunodeficiency virus HIV-1 and the amino terminal ... -
Clustering of HIV-1 Subtypes Based on gp120 V3 Loop electrostatic properties
(2012)Background: The V3 loop of the glycoprotein gp120 of HIV-1 plays an important role in viral entry into cells by utilizing as coreceptor CCR5 or CXCR4, and is implicated in the phenotypic tropisms of HIV viruses. It has ... -
Conformational properties of HIV-1 gp120/V3 immunogenic domains
(2005)Infection of target host cells by the human immunodeficiency virus-1 (HIV-1) is a multi-step process involving a series of conformational changes in the viral gp120 and gp41 proteins. Gp120 binding to the main cell receptor, ... -
Electrostatic modeling of peptides derived from the V3-loop of HIV-1 gp120: Implications of the interaction with chemokine receptor CCR5
(2007)Infection of CD4(+) T cells by macrophage-tropic HIV-1 strains involves interaction of viral gp 120 with the host cell chemokine receptor CCR5. The principle neutralizing determinant (PND) of the V3-loop of the HIV-1 gp120 ...