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Πλοήγηση ανά Θέμα "Genomics"

Αποτελέσματα 1-12 από 12

    • Drug genetic associations with COVID-19 manifestations: a data mining and network biology approach 

      Charitou T., Kontou P.I., Tamposis I.A., Pavlopoulos G.A., Braliou G.G., Bagos P.G. (2022)
      Available drugs have been used as an urgent attempt through clinical trials to minimize severe cases of hospitalizations with Coronavirus disease (COVID-19), however, there are limited data on common pharmacogenomics ...

    • Genomics of habitat choice and adaptive evolution in a deep-sea fish 

      Gaither M.R., Gkafas G.A., De Jong M., Sarigol F., Neat F., Regnier T., Moore D., Gröcke D.R., Hall N., Liu X., Kenny J., Lucaci A., Hughes M., Haldenby S., Hoelzel A.R. (2018)
      Intraspecific diversity promotes evolutionary change, and when partitioned among geographic regions or habitats can form the basis for speciation. Marine species live in an environment that can provide as much scope for ...

    • GWAR: Robust analysis and meta-analysis of genome-wide association studies 

      Dimou N.L., Tsirigos K.D., Elofsson A., Bagos P.G. (2017)
      Motivation: In the context of genome-wide association studies (GWAS), there is a variety of statistical techniques in order to conduct the analysis, but, in most cases, the underlying genetic model is usually unknown. Under ...

    • Hypoxia-Inducible Factor-2-Altered Urothelial Carcinoma: Clinical and Genomic Features 

      Vlachostergios P.J., Tamposis I.A., Anagnostou M., Papathanassiou M., Mitrakas L., Zachos I., Thodou E., Samara M., Tzortzis V. (2022)
      Background: Hypoxia is recognized as a key feature of cancer growth and is involved in various cellular processes, including proliferation, angiogenesis, and immune surveillance. Besides hypoxia-inducible factor 1-alpha ...

    • LaGomiCs - Lagomorph Genomics Consortium: An International Collaborative Effort for Sequencing the Genomes of an Entire Mammalian Order 

      Fontanesi L., Di Palma F., Flicek P., Smith A.T., Thulin C.-G., Alves P.C., Abrantes J., Andersson L., Angelone C., Boonstra R., Campos R., Carneiro M., Casadio R., Cervantes F.A., Dahal N., Djan M., Esteves P.J., Etherington G., Fan J., Fickel J., Ge D., Husband T., King T., Kovach A.I., Lavazza A., Letty J., Lissovsky A.A., Mage R., Mamuris Z., Martelli P.L., McGreevy T., Jr., Melo-Ferreira J., Muffato M., Ramakrishnan U., Randi E., Reid N., Ribani A., Robinson T.J., Russello M.A., Schiavo G., Schneider-Gricar V., Solari K.A., Streeter I., Tizzani P., Tur A., Utzeri V.J., Velickovic N., Vernesi C., Yang Q., Lagomorph Genomics Consortium (2016)
      The order Lagomorpha comprises about 90 living species, divided in 2 families: the pikas (Family Ochotonidae), and the rabbits, hares, and jackrabbits (Family Leporidae). Lagomorphs are important economically and scientifically ...

    • Molecular diversity and phylogeny of indigenous Rhizobium leguminosarum strains associated with Trifolium repens plants in Romania 

      Efrose R.C., Rosu C.M., Stedel C., Stefan A., Sirbu C., Gorgan L.D., Labrou N.E., Flemetakis E. (2018)
      The symbiotic nitrogen fixing legumes play an essential role in sustainable agriculture. White clover (Trifolium repens L.) is one of the most valuable perennial legumes in pastures and meadows of temperate regions. Despite ...

    • Multi-branch Convolutional Neural Network for Identification of Small Non-coding RNA genomic loci 

      Georgakilas G.K., Grioni A., Liakos K.G., Chalupova E., Plessas F.C., Alexiou P. (2020)
      Genomic regions that encode small RNA genes exhibit characteristic patterns in their sequence, secondary structure, and evolutionary conservation. Convolutional Neural Networks are a family of algorithms that can classify ...

    • Origins and genetic legacy of prehistoric dogs 

      Bergström A., Frantz L., Schmidt R., Ersmark E., Lebrasseur O., Girdland-Flink L., Lin A.T., Storå J., Sjögren K.-G., Anthony D., Antipina E., Amiri S., Bar-Oz G., Bazaliiskii V.I., Bulatović J., Brown D., Carmagnini A., Davy T., Fedorov S., Fiore I., Fulton D., Germonpré M., Haile J., Irving-Pease E.K., Jamieson A., Janssens L., Kirillova I., Horwitz L.K., Kuzmanović-Cvetković J., Kuzmin Y., Losey R.J., Dizdar D.L., Mashkour M., Novak M., Onar V., Orton D., Pasarić M., Radivojević M., Rajković D., Roberts B., Ryan H., Sablin M., Shidlovskiy F., Stojanović I., Tagliacozzo A., Trantalidou K., Ullén I., Villaluenga A., Wapnish P., Dobney K., Götherström A., Linderholm A., Dalén L., Pinhasi R., Larson G., Skoglund P. (2020)
      Dogs were the first domestic animal, but little is known about their population history and to what extent it was linked to humans. We sequenced 27 ancient dog genomes and found that all dogs share a common ancestry distinct ...

    • Phylogenetic analysis of bird-virulent West Nile virus strain, Greece 

      Valiakos G., Plavos K., Vontas A., Sofia M., Giannakopoulos A., Giannoulis T., Spyrou V., Tsokana C.N., Chatzopoulos D., Kantere M., Diamantopoulos V., Theodorou A., Mpellou S., Tsakris A., Mamuris Z., Billinis C. (2019)
      We report the full polyprotein genomic sequence of a West Nile virus strain isolated from Eurasian magpies dying with neurologic signs in Greece. Our findings demonstrate the local genetic evolution of the West Nile virus ...

    • Prediction and enrichment analyses of the Homo sapiens-Drosophila melanogaster COPD-related orthologs: potential for modeling of human COPD genomic responses with the fruit fly 

      Rouka E., Gourgoulianni N., Lupold S., Hatzoglou C., Gourgoulianis K.I., Zarogiannis S.G. (2022)
      The significant similarities in airway epithelial cells between mammals and the fruit fly Drosophila melanogaster have rendered the latter an important model organism for studies of chronic inflammatory lung diseases. ...

    • RNAcentral: A comprehensive database of non-coding RNA sequences 

      Petrov A.I., Kay S.J.E., Kalvari I., Howe K.L., Gray K.A., Bruford E.A., Kersey P.J., Cochrane G., Finn R.D., Bateman A., Kozomara A., Griffiths-Jones S., Frankish A., Zwieb C.W., Lau B.Y., Williams K.P., Chan P.P., Lowe T.M., Cannone J.J., Gutell R.R., Machnicka M.A., Bujnicki J.M., Yoshihama M., Kenmochi N., Chai B., Cole J.R., Szymanski M., Karlowski W.M., Wood V., Huala E., Berardini T.Z., Zhao Y., Chen R., Zhu W., Paraskevopoulou M.D., Vlachos I.S., Hatzigeorgiou A.G., Ma L., Zhang Z., Puetz J., Stadler P.F., McDonald D., Basu S., Fey P., Engel S.R., Cherry J.M., Volders P.-J., Mestdagh P., Wower J., Clark M., Quek X.C., Dinger M.E., The RNAcentral Consortium (2017)
      RNAcentral is a database of non-coding RNA (ncRNA) sequences that aggregates data from specialised ncRNA resources and provides a single entry point for accessing ncRNA sequences of all ncRNA types from all organisms. Since ...

    • Tribolium castaneum: A Model Insect for Fundamental and Applied Research 

      Campbell J.F., Athanassiou C.G., Hagstrum D.W., Zhu K.Y. (2022)
      Tribolium castaneum has a long history as a model species in many distinct subject areas, but improved connections among the genetics, genomics, behavioral, ecological, and pest management fields are needed to fully realize ...