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Browsing by Subject "GWAS"

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    • Assessment of Parkinson's disease risk loci in Greece 

      Kara, E.; Xiromerisiou, G.; Spanaki, C.; Bozi, M.; Koutsis, G.; Panas, M.; Dardiotis, E.; Ralli, S.; Bras, J.; Letson, C.; Edsall, C.; Pliner, H.; Arepalli, S.; Kalinderi, K.; Fidani, L.; Bostantjopoulou, S.; Keller, M. F.; Wood, N. W.; Hardy, J.; Houlden, H.; Stefanis, L.; Plaitakis, A.; Hernandez, D.; Hadjigeorgiou, G. M.; Nalls, M. A.; Singleton, A. B. (2014)
      Genome-wide association studies (GWAS) have been shown to be a powerful approach to identify risk loci for neurodegenerative diseases. Recent GWAS in Parkinson's disease (PD) have been successful in identifying numerous ...

    • Genetic model selection in genome-wide association studies: robust methods and the use of meta-analysis 

      Bagos, P. G. (2013)
      In genetic association studies (GAS) as well as in genome-wide association studies (GWAS), the mode of inheritance (dominant, additive and recessive) is usually not known a priori. Assuming an incorrect mode of inheritance ...

    • Meta-Analysis of Family-Based and Case-Control Genetic Association Studies that Use the Same Cases 

      Bagos, P. G.; Dimou, N. L.; Liakopoulos, T. D.; Nikolopoulos, G. K. (2011)
      In many cases in genetic epidemiology, the investigators in an effort to control for different sources of confounding and simultaneously to increase the power perform a family-based and a population-based case-control study ...