• Activation of FADD-Dependent neuronal death pathways as a predictor of pathogenicity for LRRK2 mutations 

      Melachroinou K., Leandrou E., Valkimadi P.-E., Memou A., Hadjigeorgiou G., Stefanis L., Rideout H.J. (2016)
      Background Despite the plethora of sequence variants in LRRK2, only a few clearly segregate with PD. Even within this group of pathogenic mutations, the phenotypic profile can differ widely. Objective We examined multiple ...
    • Genetic variations in the SULF1 gene alter the risk of cervical cancer and precancerous lesions 

      Dardiotis E., Siokas V., Garas A., Paraskevaidis E., Kyrgiou M., Xiromerisiou G., Deligeoroglou E., Galazios G., Kontomanolis E.N., Spandidos D.A., Tsatsakis A., Daponte A. (2018)
      Human papillomavirus (HPV) infection alone is not sufficient to explain the development of cervical cancer. Genetic variants have been linked to the development of precancerous lesions and cervical cancer. In this study, ...
    • Toll-like receptors and their role in renal pathologies 

      Eleftheriadis, T.; Pissas, G.; Liakopoulos, V.; Stefanidis, I.; Lawson, B. R. (2012)
      Toll-like receptors (TLRs) are the first identified and best studied family of pattern recognition receptors. Expressed in immunocytes, TLRs initiate innate immune responses and concurrently shape the subsequent adaptive ...