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Πλοήγηση ανά Θέμα "COS Cells"

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    • Boswellic acids and their derivatives as potent regulators of glucocorticoid receptor actions 

      Karra A.G., Tziortziou M., Kylindri P., Georgatza D., Gorgogietas V.A., Makiou A., Krokida A., Tsialtas I., Kalousi F.D., Papadopoulos G.E., Papadopoulou K.Κ., Psarra A.-M.G. (2020)
      Glucocorticoid (GCs) hormones exert their actions via their cognate steroid receptors the Glucocorticoid Receptors (GR), by genomic or non-genomic mechanisms of actions. GCs regulate many cellular functions among them ...

    • Functional characterization of the hGRαT556I causing Chrousos syndrome 

      Nicolaides N.C., Skyrla E., Vlachakis D., Psarra A.-M.G., Moutsatsou P., Sertedaki A., Kossida S., Charmandari E. (2016)
      Background: Chrousos syndrome is a rare pathologic condition characterized by generalized, partial resistance of target tissues to glucocorticoids and caused by inactivating mutations of the human glucocorticoid receptor ...

    • Potential dissociative glucocorticoid receptor activity for protopanaxadiol and protopanaxatriol 

      Karra A.G., Konstantinou M., Tzortziou M., Tsialtas I., Kalousi F.D., Garagounis C., Hayes J.M., Psarra A.-M.G. (2019)
      �Glucocorticoids are steroid hormones that regulate inflammation, growth, metabolism, and apoptosis via their cognate receptor, the glucocorticoid receptor (GR). GR, acting mainly as a transcription factor, activates or ...