• aMAP risk score predicts hepatocellular carcinoma development in patients with chronic hepatitis 

      Fan R., Papatheodoridis G., Sun J., Innes H., Toyoda H., Xie Q., Mo S., Sypsa V., Guha I.N., Kumada T., Niu J., Dalekos G., Yasuda S., Barnes E., Lian J., Suri V., Idilman R., Barclay S.T., Dou X., Berg T., Hayes P.C., Flaherty J.F., Zhou Y., Zhang Z., Buti M., Hutchinson S.J., Guo Y., Calleja J.L., Lin L., Zhao L., Chen Y., Janssen H.L.A., Zhu C., Shi L., Tang X., Gaggar A., Wei L., Jia J., Irving W.L., Johnson P.J., Lampertico P., Hou J. (2020)
      Background & Aims: Hepatocellular carcinoma (HCC) is the leading cause of death in patients with chronic hepatitis. In this international collaboration, we sought to develop a global universal HCC risk score to predict the ...
    • Enhanced erythrocyte antioxidant status following an 8-week aerobic exercise training program in heavy drinkers 

      Georgakouli K., Manthou E., Fatouros I.G., Georgoulias P., Deli C.K., Koutedakis Y., Theodorakis Y., Jamurtas A.Z. (2018)
      Alcohol-induced oxidative stress is involved in the development and progression of various pathological conditions and diseases. On the other hand, exercise training has been shown to improve redox status, thus attenuating ...
    • Factors Associated With Progression and Outcomes of Early Stage Primary Biliary Cholangitis 

      Gatselis N.K., Goet J.C., Zachou K., Lammers W.J., Janssen H.L.A., Hirschfield G., Corpechot C., Lindor K.D., Invernizzi P., Mayo M.J., Battezzati P.M., Floreani A., Pares A., Lygoura V., Nevens F., Mason A.L., Kowdley K.V., Ponsioen C.Y., Bruns T., Thorburn D., Verhelst X., Harms M.H., van Buuren H.R., Hansen B.E., Dalekos G.N., Global Primary Biliary Cholangitis Study Group (2020)
      Background & Aims: Patients usually receive a diagnosis of primary biliary cholangitis (PBC) at an early stage, based on biochemical analyses. We investigated the proportion of patients who progress to moderate or advanced ...
    • Goals of Treatment for Improved Survival in Primary Biliary Cholangitis: Treatment Target Should Be Bilirubin within the Normal Range and Normalization of Alkaline Phosphatase 

      Murillo Perez C.F., Harms M.H., Lindor K.D., Van Buuren H.R., Hirschfield G.M., Corpechot C., Van Der Meer A.J., Feld J.J., Gulamhusein A., Lammers W.J., Ponsioen C.Y., Carbone M., Mason A.L., Mayo M.J., Invernizzi P., Battezzati P.M., Floreani A., Lleo A., Nevens F., Kowdley K.V., Bruns T., Dalekos G.N., Gatselis N.K., Thorburn D., Trivedi P.J., Verhelst X., Parés A., Janssen H.L.A., Hansen B.E. (2020)
      INTRODUCTION:In primary biliary cholangitis (PBC), bilirubin and alkaline phosphatase (ALP) are widely established as independent predictors of prognosis. Current treatment goals do not aim for normalization of surrogate ...