Πλοήγηση ανά Συγγραφέα "Tsotinis, A."
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Conformational analysis of two novel cytotoxic C2-substituted pyrrolo 2,3-f quinolines in aqueous media, organic solvents, membrane bilayers and at the putative active site
Varvarigou, N.; Megariotis, G.; Leonis, G.; Vrontaki, E.; Maniati, A. M.; Vlachou, M.; Eikosipentaki, A.; Kompogennitaki, R.; Papadopoulos, M. G.; Grdadolnik, S. G.; Komiotis, D.; Mavromoustakos, T.; Tsotinis, A. (2012)We have performed: (i) conformational analysis of two novel cytotoxic C2-substituted pyrrolo[2,3-f]quinolines Se and 5g in deuterated dimethylsulfoxide (DMSO-d(6)) utilizing NOE results from NMR spectroscopy; (ii) molecular ... -
Unsaturation: An important structural feature to nucleosides' antiviral activity
Manta, S.; Kiritsis, C.; Dimopoulou, A.; Parmenopoulou, V.; Kollatos, N.; Tsotinis, A.; Komiotis, D. (2014)In the search of effective, selective and nontoxic antiviral agents, a variety of nucleoside analogues have been synthesized, with different functionalities in the carbohydrate moiety and/or the heterocyclic base. Nucleoside ...