Πλοήγηση ανά Συγγραφέα "Tsilioni, I."
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8-Isoprostane levels in serum and bronchoalveolar lavage in idiopathic pulmonary fibrosis and sarcoidosis
Malli, F.; Bardaka, F.; Tsilioni, I.; Karetsi, E.; Gourgoulianis, K. I.; Daniil, Z. (2013)Objective and design: Sarcoidosis and idiopathic pulmonary fibrosis (IPF) are both associated with deregulated inflammatory mechanisms partially triggered by aggravated oxidative stress. 8-Isoprostane has been proposed as ... -
The acute effect of smoking in healthy and asthmatic smokers
Papaioannou, A. I.; Koutsokera, A.; Tanou, K.; Kiropoulos, T. S.; Tsilioni, I.; Oikonomidi, S.; Liadaki, K.; Pournaras, S.; Gourgoulianis, K. I.; Kostikas, K. (2010)Background Acute exposure to cigarette smoke is related to airway and systemic inflammation and oxidative stress. Little is known about the acute effect of cigarette smoking in smoking asthmatics. The aim of this study was ... -
Acute phase markers for the differentiation of infectious and malignant pleural effusions
Kiropoulos, T. S.; Kostikas, K.; Oikonomidi, S.; Tsilioni, I.; Nikoulis, D.; Germenis, A.; Gourgoulianis, K. I. (2007)Acute-phase markers, such as C-reactive protein (CRP), interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α), have been studied in inflammatory and malignant disorders. We examined the diagnostic value of these ... -
Clinical significance of cytokines levels in exhaled breath condensate (EBC) and serum of lung cancer patients
Lamprodimou, G.; Athanasiadis, A.; Kerenidi, T.; Doufexis, D.; Lada, M.; Tsilioni, I.; Roussos, G.; Vavougios, G.; Gourgoulianis, K. (2013) -
Diagnostic accuracy of biomarkers of oxidative stress in parapneumonic pleural effusions
Tsilioni, I.; Kostikas, K.; Kalomenidis, I.; Oikonomidi, S.; Tsolaki, V.; Minas, M.; Gourgoulianis, K. I.; Kiropoulos, T. S. (2011)P>Background The imbalance between oxidants and antioxidants is referred to as oxidative stress and has been associated with various respiratory disorders. The aim of this study was the assessment of 8-isoprostane (8-iso-PGF(2 ... -
The DJ-1 protein as a candidate biomarker in obstructive sleep apnea syndrome
Vavougios, G.; Pastaka, C.; Tsilioni, I.; Natsios, G.; Seitanidis, G.; Florou, E.; Gourgoulianis, K. I. (2014)Oxidative stress has a central role in the pathophysiology of obstructive sleep apnea syndrome (OSAS). The DJ-1 protein functions as a sensor of oxidative stress, acting both as a reactive oxygen species scavenger (ROS) ... -
Endothelial Progenitor Cells in the Pathogenesis of Idiopathic Pulmonary Fibrosis: An Evolving Concept
Malli, F.; Koutsokera, A.; Paraskeva, E.; Zakynthinos, E.; Papagianni, M.; Makris, D.; Tsilioni, I.; Molyvdas, P. A.; Gourgoulianis, K. I.; Daniil, Z. (2013)Background: Idiopathic pulmonary fibrosis (IPF) has been associated with abnormal vascular remodeling. Bone marrow derived endothelial progenitor cells (EPCs) are considered to possess lung tissue repair and vascular ... -
Hyaluronic acid levels are increased in complicated parapneumonic pleural effusions
Zaga, T.; Makris, D.; Tsilioni, I.; Kiropoulos, T.; Oikonomidi, S.; Damianos, A.; Gourgoulianis, K. I. (2011)Background and Aim. Hyaluronic acid (HA) is a component of extracellular matrix and may play a role in the pleural inflammation which is implicated in parapneumonic effusions.The aim of the current study was to investigate ... -
Interleukin-27 improves the ability of adenosine deaminase to rule out tuberculous pleural effusion regardless of pleural tuberculosis prevalence
Skouras, V. S.; Magkouta, S. F.; Psallidas, I.; Tsilioni, I.; Maragozidis, P.; Gourgoulianis, K. I.; Kalomenidis, I. (2015)Background: Interleukin-27 (IL-27) has been proposed to be useful for diagnosing tuberculous pleural effusion (TPE). Adenosine deaminase (ADA) has been long used for the same purpose. The aim of this study was to compare ... -
Matrix Metalloproteinase Levels in the Differentiation of Parapneumonic Pleural Effusions
Oikonomidi, S.; Kostikas, K.; Kalomenidis, I.; Tsilioni, I.; Daenas, C.; Gourgoulianis, K. I.; Kiropoulos, T. S. (2010)Background: Matrix metalloproteinases (MMPs) have been implicated in the escalation of fibrosis and remodeling which are central to the subsequent progression of a parapneumonic pleural effusion to empyema. Objectives: The ... -
Matrix Metalloproteinases in Respiratory Diseases: From Pathogenesis to Potential Clinical Implications
Oikonomidi, S.; Kostikas, K.; Tsilioni, I.; Tanou, K.; Gourgoulianis, K. I.; Kiropoulos, T. S. (2009)Matrix metalloproteinases (MMPs) are zinc-endopeptidases responsible for degradation of the extracellular matrix (ECM) components including basement membrane collagen, interstitial collagen, fibronectin, and various ... -
Non-Invasive Ventilation (NIV) and Homeostatic Model Assessment (HOMA) Index in Stable Chronic Obstructive Pulmonary Disease (COPD) Patients with Chronic Hypercapnic Respiratory Failure: A Pilot Study
Dimoulis, A.; Pastaka, C.; Tsolaki, V.; Tsilioni, I.; Pournaras, S.; Liakos, N.; Georgoulias, P.; Gourgoulianis, K. (2015)The effects of Non-invasive Ventilation (NIV) on Insulin Resistance (IR) in stable Chronic Obstructive Pulmonary Disease (COPD) patients have not been fully explored. The aim of this study was to assess the effects of NIV ... -
Obstructive Sleep Apnea, Excessive Daytime Sleepiness, and Morning Plasma TNF-alpha Levels in Greek Children
Alexopoulos, E. I.; Theologi, V.; Malakasioti, G.; Maragozidis, P.; Tsilioni, I.; Chrousos, G.; Gourgoulianis, K.; Kaditis, A. G. (2013)Background: Obstructive sleep apnea (OSA) has been associated with increased frequency of excessive daytime sleepiness (EDS). Increased plasma TNF-alpha levels may mediate this association in adults, but conflicting results ... -
OSMOTIC STRESS ALTERS THE PERMEABILITY OF THE PLEURA AND THE MIGRATION PROPERTIES OF MESOTHELIAL CELLS
Peppa, V.; Solenov, E.; Tsilioni, I.; Kalomenidis, I.; Molyvdas, P. A.; Gourgoulianis, K.; Hatzoglou, C.; Zarogiannis, S. G. (2014) -
Oxidative stress in patients with obstructive sleep apnea syndrome
Ntalapascha, M.; Makris, D.; Kyparos, A.; Tsilioni, I.; Kostikas, K.; Gourgoulianis, K.; Kouretas, D.; Zakynthinos, E. (2013)We aimed to investigate whether systemic oxidative stress is increased in patients with obstructive sleep apnea syndrome (OSAS). A total of 18 patients with severe OSAS and 13 controls were included in the study. Inclusion ... -
Pleural fluid protein is inversely correlated with age in uncomplicated parapneumonic pleural effusions
Zarogiannis, S. G.; Tsilioni, I.; Hatzoglou, C.; Molyvdas, P. A.; Gourgoulianis, K. I. (2013)Objectives: Assess whether age influences standard biochemical parameters used in the differential diagnosis of transudative and exudative pleural effusions. Design and methods: We retrospectively analyzed data from the ... -
Residual Pleural Thickening Is Related to Vascular Endothelial Growth Factor Levels in Parapneumonic Pleural Effusions
Papaioannou, A. I.; Kostikas, K.; Tsopa, P.; Kiropoulos, T.; Tsilioni, I.; Oikonomidi, S.; Gerogianni, I.; Gourgoulianis, K. I. (2010)Background: Many patients with pneumonia develop pleural effusions. Pleural fluid vascular endothelial growth factor (VEGF) levels are known to be elevated in complicated parapneumonic effusion and seem to play a major ... -
Serum Amyloid Alpha in Parapneumonic Effusions
Boultadakis, V.; Skouras, V.; Makris, D.; Damianaki, A.; Nikoulis, D. J.; Kiropoulos, T.; Oikonomidi, S.; Tsilioni, I.; Gourgoulianis, K. (2011)Study objectives. To assess serum amyloid alpha (SAA) pleural fluid levels in parapneumonic effusion (PPE) and to investigate SAA diagnostic performance in PPE diagnosis and outcome. Methods. We studied prospectively 57 ... -
Systemic and airway inflammation and the presence of emphysema in patients with COPD
Papaioannou, A. I.; Mazioti, A.; Kiropoulos, T.; Tsilioni, I.; Koutsokera, A.; Tanou, K.; Nikoulis, D. J.; Georgoulias, P.; Zakynthinos, E.; Gourgoulianis, K. I.; Kostikas, K. (2010)The aim of this study was to determine the impact of HRCT-confirmed emphysema on biomarkers evaluating airway and systemic inflammation in COPD patients. Forty-nine consecutive male COPD outpatients with stable COPD were ... -
Urine Concentrations of Cysteinyl Leukotrienes in Children with Obstructive Sleep-Disordered Breathing
Kaditis, A.; Chaidas, K.; Alexopoulos, E.; Ntamagka, G.; Karathanasi, A.; Boultadakis, E.; Kiropoulos, T.; Tsilioni, I.; Gourgoulianis, K. (2009)