Sfoglia per Autore "Nikolopoulos, G. K."
Items 1-12 di 12
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The association between plasminogen activator inhibitor type 1 (PAI-1) levels, PAI-1 4G/5G polymorphism, and myocardial infarction: a Mendelian randomization meta-analysis
Nikolopoulos, G. K.; Bagos, P. G.; Tsangaris, I.; Tsiara, C. G.; Kopterides, P.; Vaiopoulos, A.; Kapsimali, V.; Bonovas, S.; Tsantes, A. E. (2014)Background: The circulating levels of plasminogen activator inhibitor type 1 (PAI-1) are increased in individuals carrying the 4G allele at position -675 of the PAI-1 gene. In turn, overexpression of PAI-1 has been found ... -
Cytokine gene polymorphisms in multiple sclerosis: a meta-analysis of 45 studies including 7379 cases and 8131 controls
Nikolopoulos, G. K.; Masgala, A.; Tsiara, C.; Limitsiou, O. K.; Karnaouri, A. C.; Dimou, N. L.; Bagos, P. G. (2011)Many environmental and genetic factors have been implicated in the development of multiple sclerosis. However, the aetiology has not been clarified yet. Therefore, using a meta-analytic approach, we tried to probe the ... -
Cytokine gene polymorphisms in periodontal disease: a meta-analysis of 53 studies including 4178 cases and 4590 controls
Nikolopoulos, G. K.; Dimou, N. L.; Hamodrakas, S. J.; Bagos, P. G. (2008)Aim: We conducted a systematic review and a meta-analysis, in order to investigate the potential association of cytokine gene polymorphisms with either aggressive or chronic periodontal disease. Material and Methods: A ... -
Developing the Evidence Base for Cancer Chemoprevention: Use of Meta-Analysis
Nikolopoulos, G. K.; Bagos, P. G.; Bonovas, S. (2011)Meta-analysis is a quantitative approach for systematically combining the results of previous studies in order to arrive at conclusions about the body of research. It answers a specific research question, includes an ... -
Effect of angiotensin converting enzyme gene I/D polymorphism and its expression on clinical outcome in acute respiratory distress syndrome
Tsantes, A. E.; Kopterides, P.; Bonovas, S.; Bagos, P.; Antonakos, G.; Nikolopoulos, G. K.; Gialeraki, A.; Kapsimali, V.; Kyriakou, E.; Kokori, S.; Dima, K.; Armaganidis, A.; Tsangaris, I. (2013)Background. The role of the D allele of the angiotensin-converting enzyme (ACE) gene I/D polymorphism in the clinical outcomes of patients with acute lung injury and acute respiratory distress syndrome (ALI/ARDS) remains ... -
Effect of hepatitis C virus on immunological and virological responses in HIV-infected patients initiating highly active antiretroviral therapy: a meta-analysis
Tsiara, C. G.; Nikolopoulos, G. K.; Dimou, N. L.; Bagos, P. G.; Saroglou, G.; Velonakis, E.; Hatzakis, A. (2013)Co-infection of human immunodeficiency virus (HIV) with hepatitis C virus (HCV) is rather common. In the era of highly active antiretroviral therapy (HAART), viral hepatitis could result in adverse outcomes in HIV+ patients. ... -
Fc gamma receptor polymorphisms and their association with periodontal disease: a meta-analysis
Dimou, N. L.; Nikolopoulos, G. K.; Hamodrakas, S. J.; Bagos, P. G. (2010)Aim: A systematic review and a meta-analysis were conducted in order to investigate the potential association of Fc gamma receptor (Fc gamma R) polymorphisms with susceptibility to aggressive and chronic periodontal disease. ... -
Generalized least squares for assessing trends in cumulative meta-analysis with applications in genetic epidemiology
Bagos, P. G.; Nikolopoulos, G. K. (2009)Objective: Cumulative meta-analysis allows the evaluation of a study's contribution to the combined effect of the preceding research. It accrues evidence, gradually adding studies one at a time and provides updated estimates ... -
Impact of HIV Type 1 DNA Levels on Spontaneous Disease Progression: A Meta-Analysis
Tsiara, C. G.; Nikolopoulos, G. K.; Bagos, P. G.; Goujard, C.; Katzenstein, T. L.; Minga, A. K.; Rouzioux, C.; Hatzakis, A. (2012)Several studies have reported the prognostic strength of HIV-1 DNA with variable results however. The aims of the current study were to estimate more accurately the ability of HIV-1 DNA to predict progression of HIV-1 ... -
Meta-Analysis of Family-Based and Case-Control Genetic Association Studies that Use the Same Cases
Bagos, P. G.; Dimou, N. L.; Liakopoulos, T. D.; Nikolopoulos, G. K. (2011)In many cases in genetic epidemiology, the investigators in an effort to control for different sources of confounding and simultaneously to increase the power perform a family-based and a population-based case-control study ... -
A method for meta-analysis of case-control genetic association studies using logistic regression
Bagos, P. G.; Nikolopoulos, G. K. (2007)We propose here a simple and robust approach for meta-analysis of molecular association studies. Making use of the binary structure of the data, and by treating the genotypes as independent variables in a logistic regression, ... -
Use of Fibrates and Cancer Risk: A Systematic Review and Meta-Analysis of 17 Long-Term Randomized Placebo-Controlled Trials
Bonovas, S.; Nikolopoulos, G. K.; Bagos, P. G. (2012)Background: Fibrates comprise a class of well-established antilipidemic agents that significantly reduce cardiovascular events. Given the concerns of cancer with fibrate therapy, we undertook a systematic review and ...