• It is safe to use transdermal glyceryl trinitrate to lower blood pressure in patients with acute ischaemic stroke with carotid stenosis 

      Appleton J.P., Woodhouse L.J., Belcher A., Bereczki D., Berge E., Caso V., Chang H.M., Christensen H.K., Collins R., Gommans J., Laska A.C., Ntaios G., Ozturk S., Sare G.M., Szatmari S., Wang Y., Wardlaw J.M., Sprigg N., Bath P.M. (2019)
      Background There is concern that blood pressure (BP) lowering in acute stroke may compromise cerebral perfusion and worsen outcome in the presence of carotid stenosis. We assessed the effect of glyceryl trinitrate (GTN) ...
    • PRECIOUS: PREvention of Complications to Improve OUtcome in elderly patients with acute Stroke. Rationale and design of a randomised, open, phase III, clinical trial with blinded outcome assessment 

      Reinink H., de Jonge J.C., Bath P.M., van de Beek D., Berge E., Borregaard S., Ciccone A., Csiba L., Demotes J., Dippel D.W., Kõrv J., Kurkowska-Jastrzebska I., Lees K.R., Macleod M.R., Ntaios G., Randall G., Thomalla G., van der Worp H.B. (2018)
      Background: Elderly patients are at high risk of complications after stroke, such as infections and fever. The occurrence of these complications has been associated with an increased risk of death or dependency. Hypothesis: ...
    • Prediction of large vessel occlusions in acute stroke: National institute of health stroke scale is hard to beat 

      Vanacker P., Heldner M.R., Amiguet M., Faouzi M., Cras P., Ntaios G., Arnold M., Mattle H.P., Gralla J., Fischer U., Michel P. (2016)
      Objectives: Endovascular treatment for acute ischemic stroke with a large vessel occlusion was recently shown to be effective. We aimed to develop a score capable of predicting large vessel occlusion eligible for endovascular ...
    • Prediction of long-term outcomes by arterial stiffness and pressure wave reflections in patients with acute stroke: the Athens Stroke Registry 

      Samara S., Vemmou A., Kyrkou A., Papamichael C., Korompoki E., Ntaios G., Manios E., Stamatelopoulos K., Protogerou A.D., Vemmos K. (2022)
      Background and purpose: Stroke patients' management might be improved by addressing the role of aortic stiffness (carotid-femoral pulse wave velocity: cfPWV) and pressure wave reflections (PWRs, augmentation index: AIx) ...
    • Prior Dual Antiplatelet Therapy and Thrombolysis in Acute Stroke 

      Altersberger V.L., Sturzenegger R., Räty S., Hametner C., Scheitz J.F., Moulin S., van den Berg S.A., Zini A., Nannoni S., Heldner M.R., Jovanovic D.R., Martinez-Majander N., Tiainen M., Valkonen K., Berberich A., Erdur H., Cordonnier C., Peters N., Gopisingh K.M., Bigliardi G., Strambo D., De Marchis G.M., Ntaios G., Cereda C.W., Wegener S., Kägi G., Pezzini A., Padjen V., Arnold M., Michel P., Vandelli L., Nederkoorn P.J., Leys D., Nolte C.H., Ringleb P.A., Curtze S., Engelter S.T., Gensicke H. (2020)
      [No abstract available]
    • Recurrent Ischemic Stroke and Bleeding in Patients With Atrial Fibrillation Who Suffered an Acute Stroke While on Treatment With Nonvitamin K Antagonist Oral Anticoagulants: The RENO-EXTEND Study 

      Paciaroni M., Caso V., Agnelli G., Mosconi M.G., Giustozzi M., Seiffge D.J., Engelter S.T., Lyrer P., Polymeris A.A., Kriemler L., Zietz A., Putaala J., Strbian D., Tomppo L., Michel P., Strambo D., Salerno A., Remillard S., Buehrer M., Bavaud O., Vanacker P., Zuurbier S., Yperzeele L., Loos C.M.J., Cappellari M., Emiliani A., Zedde M., Abdul-Rahim A., Dawson J., Cronshaw R., Schirinzi E., Del Sette M., Stretz C., Kala N., Reznik M., Schomer A., Grory B.M., Jayaraman M., Mctaggart R., Yaghi S., Furie K.L., Masotti L., Grifoni E., Toni D., Risitano A., Falcou A., Petraglia L., Lotti E.M., Padroni M., Pavolucci L., Lochner P., Silvestrelli G., Ciccone A., Alberti A., Venti M., Traballi L., Urbini C., Kargiotis O., Rocco A., Diomedi M., Marcheselli S., Caliandro P., Zauli A., Reale G., Antonenko K., Rota E., Tassinari T., Saia V., Palmerini F., Aridon P., Arnao V., Monaco S., Cottone S., Baldi A., D'Amore C., Ageno W., Pegoraro S., Ntaios G., Sagris D., Giannopoulos S., Kosmidou M., Ntais E., Romoli M., Pantoni L., Rosa S., Bertora P., Chiti A., Canavero I., Saggese C.E., Plocco M., Giorli E., Palaiodimou L., Bakola E., Tsivgoulis G., Bandini F., Gasparro A., Terruso V., Mannino M., Pezzini A., Ornello R., Sacco S., Popovic N., Scoditti U., Genovese A., Denti L., Flomin Y., Mancuso M., Ferrari E., Caselli M.C., Ulivi L., Giannini N., De Marchis G.M. (2022)
      BACKGROUND: In patients with atrial fibrillation who suffered an ischemic stroke while on treatment with nonvitamin K antagonist oral anticoagulants, rates and determinants of recurrent ischemic events and major bleedings ...
    • Relationship between nitrate headache and outcome in patients with acute stroke: Results from the efficacy of nitric oxide in stroke (ENOS) trial 

      Beishon L., Woodhouse L.J., Bereczki D., Christensen H.K., Collins R., Gommans J., Kruuse C., Ntaios G., Ozturk S., Phillips S., Pocock S., Szatmari S., Wardlaw J., Sprigg N., Bath P.M. (2021)
      Introduction Nitrate-induced headache is common and may signify responsive cerebral vasculature. We assessed the relationship between nitrate headache and outcome in patients with acute stroke. Materials and methods Patients ...
    • Rivaroxaban versus aspirin for secondary prevention of ischaemic stroke in patients with cancer: a subgroup analysis of the NAVIGATE ESUS randomized trial 

      Martinez-Majander N., Ntaios G., Liu Y.Y., Ylikotila P., Joensuu H., Saarinen J., Perera K.S., Marti-Fabregas J., Chamorro A., Rudilosso S., Prats-Sanchez L., Berkowitz S.D., Mundl H., Themeles E., Tiainen M., Demchuk A., Kasner S.E., Hart R.G., Tatlisumak T., the NAVIGATE ESUS investigators (2020)
      Background and purpose: Cancer is a frequent finding in ischaemic stroke patients. The frequency of cancer amongst participants in the NAVIGATE ESUS randomized trial and the distribution of outcome events during treatment ...
    • Route of Feeding as a Proxy for Dysphagia After Stroke and the Effect of Transdermal Glyceryl Trinitrate: Data from the Efficacy of Nitric Oxide in Stroke Randomised Controlled Trial 

      Woodhouse L.J., Scutt P., Hamdy S., Smithard D.G., Cohen D.L., Roffe C., Bereczki D., Berge E., Bladin C.F., Caso V., Christensen H.K., Collins R., Czlonkowska A., de Silva A., Etribi A., Laska A.-C., Ntaios G., Ozturk S., Phillips S.J., Prasad K., Szatmari S., Sprigg N., Bath P.M. (2018)
      Post-stroke dysphagia is common, associated with poor outcome and often requires non-oral feeding/fluids. The relationship between route of feeding and outcome, as well as treatment with glyceryl trinitrate (GTN), was ...
    • Small-vessel occlusion versus large-artery atherosclerotic strokes in diabetics: Patient characteristics, outcomes, and predictors of stroke mechanism 

      Ntaios G., Milionis H., Vemmos K., Makaritsis K., Ferrari J., Strbian D., Curtze S., Tatlisumak T., Michel P., Papavasileiou V. (2016)
      Introduction: Diabetes mellitus exerts a detrimental effect on cerebral vasculature affecting both macrovasculature and microvasculature. However, although ischaemic stroke is typically included among macrovascular diabetic ...
    • Terson hemorrhage in patients suffering aneurysmal subarachnoid hemorrhage: Predisposing factors and prognostic significance 

      Fountas, K. N.; Kapsalaki, E. Z.; Lee, G. P.; Machinis, T. G.; Grigorian, A. A.; Robinson Jr, J. S.; Vergados, I.; Theodosiadis, P. G. (2008)
      Object. The association of vitreous and/or subhyaloid hemorrhage with aneurysmal subarachnoid hemorrhage (SAH) has been frequently identified since the original description by Terson in 1900. In this prospective clinical ...
    • Thrombolysis in stroke patients with elevated inflammatory markers 

      Altersberger V.L., Enz L.S., Sibolt G., Hametner C., Nannoni S., Heldner M.R., Stolp J., Jovanovic D.R., Zini A., Pezzini A., Wegener S., Cereda C.W., Ntaios G., Räty S., Gumbinger C., Heyse M., Polymeris A.A., Zietz A., Schaufelbuehl A., Strambo D., Padlina G., Slavova N., Tiainen M., Valkonen K., Velzen T.J., Bigliardi G., Stanarcevic P., Magoni M., Luft A., Bejot Y., Vandelli L., Padjen V., Nederkoorn P.J., Arnold M., Michel P., Ringleb P.A., Curtze S., Engelter S.T., Gensicke H., for the Thrombolysis in Stroke Patients (TRISP) collaborators (2022)
      Objective: To investigate the prognostic value of white blood cell count (WBC) on functional outcome, mortality and bleeding risk in stroke patients treated with intravenous thrombolysis (IVT). Methods: In this prospective ...
    • Timing of initiation of oral anticoagulants in patients with acute ischemic stroke and atrial fibrillation comparing posterior and anterior circulation strokes 

      Paciaroni M., Agnelli G., Giustozzi M., Tsivgoulis G., Yaghi S., Grory B.M., Furie K.L., Tadi P., Zedde M., Abdul-Rahim A.H., Dawson J., Lees K.R., Alberti A., Venti M., Acciarresi M., D’Amore C., Mosconi M.G., Bogini V., Cappellari M., Rigatelli A., Bonetti B., Putaala J., Tomppo L., Tatlisumak T., Bandini F., Marcheselli S., Pezzini A., Poli L., Padovani A., Masotti L., Grifoni E., Vannucchi V., Sohn S.-I., Lorenzini G., Tassi R., Guideri F., Acampa M., Martini G., Ntaios G., Athanasakis G., Makaritsis K., Karagkiozi E., Vadikolias K., Liantinioti C., Palaiodimou L., Mumoli N., Porta C., Galati F., Sacco S., Tiseo C., Corea F., Ageno W., Bellesini M., Silvestrelli G., Ciccone A., Scoditti U., Denti L., Mancuso M., Caselli M.C., Maccarrone M., Ulivi L., Orlandi G., Giannini N., Tassinari T., Lodovici M.L.D., Rueckert C., Baldi A., Toni D., Gentile L., Letteri F., Giuntini M., Lotti E.M., Flomin Y., Pieroni A., Kargiotis O., Karapanayiotides T., Monaco S., Mannino M., Baronello M.M., Csiba L., Szabó L., Chiti A., Giorli E., Sette M.D., Schirinzi E., Imberti D., Zabzuni D., Doronin B., Volodina V., Michel P., Eskandari A., Vanacker P., Barlinn K., Barlinn J., Deleu D., Gourbali V., Caso V. (2020)
      Introduction: The aim of this study in patients with acute posterior ischaemic stroke (PS) and atrial fibrillation (AF) was to evaluate (1) the risks of recurrent ischaemic event and severe bleeding and (2) these risks in ...