Sfoglia per Soggetto "Flavonoids"
Items 1-20 di 24
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Bioactive compounds content and antimicrobial activities of wild edible Asteraceae species of the Mediterranean flora under commercial cultivation conditions
(2019)Nine wild edible species belonging to Astreaceae family, native to the Mediterranean basin were tested for their chemical composition (phenolic compounds, tocopherols, and organic acids) and antimicrobial activities over ... -
Bioactive properties of Sanguisorba minor L. cultivated in central Greece under different fertilization regimes
(2020)In this study, the chemical characterization and bioactive properties of S. minor cultivated under different fertilization rates (control, half rate and full rate) were evaluated. Twenty-two phenolic compounds were identified, ... -
The compositional aspects of edible flowers as an emerging horticultural product
(2021)Edible flowers are becoming very popular, as consumers are seeking healthier and more attractive food products that can improve their diet aesthetics and diversify their dietary sources of micronutrients. The great variety ... -
Development of sodium propionate-based deep eutectic solvents for polyphenol extraction from onion solid wastes
(2019)Abstract: The objective of the study presented herein was the optimisation of onion solid waste (OSW) polyphenol extraction, using sodium propionate-based deep eutectic solvents (DESs) and process variables optimised through ... -
The dietary flavonoid kaempferol effectively inhibits HIF-1 activity and hepatoma cancer cell viability under hypoxic conditions
(2010)Hepatocellular carcinoma (HCC) is characterized by high mortality rates and resistance to conventional treatment. HCC tumors usually develop local hypoxia, which stimulates proliferation of cancer cells and renders them ... -
Dietary prenylated flavonoid xanthohumol alleviates oxidative damage and accelerates diabetic wound healing via Nrf2 activation
(2022)Diabetic skin ulcer is one of the most common complications in patients suffering diabetes mellitus. Xanthohumol (XN), a hop-derived prenylated dietary flavonoid, has multiple health beneficial bioactivities. In the present ... -
Effect of Leguminosae family plant extracts and polyphenolic fractions on topoisomerase I-induced nicking of DNA
(2008)Topoisomerase I constitutes one of the enzymes playing crucial role in replication, transcription, recombination, chromosome condensation and maintenance of genome stability. Because it is an essential enzyme for vital ... -
Effects of plant phenolics and grape extracts from Greek varieties of Vitis vinifera on Mitomycin C and topoisomerase I-induced nicking of DNA
(2005)In recent years, a number of reports have shown the anticancer activity of grape extracts and wine against various types of cancer such as breast, lung and gastric cancer. This property is mainly attributed to the plant ... -
Extracts from the mediterranean food plants Carthamus lanatus, Cichorium intybus, and Cichorium spinosum enhanced GSH levels and increased Nrf2 expression in human endothelial cells
(2018)The Mediterranean diet is considered to prevent several diseases. In the present study, the antioxidant properties of six extracts from Mediterranean plant foods were assessed. The extracts' chemical composition analysis ... -
Inhibition of calcitriol inactivating enzyme CYP24A1 gene expression by flavonoids in hepatocellular carcinoma cells under normoxia and hypoxia
(2021)A vast number of epidemiological, preclinical and in vitro experimental data strongly indicate the anticancer potential of calcitriol, the biologically active form of vitamin D. However, for the implementation of a vitamin ... -
Inhibition of ozone-induced SP-A oxidation by plant polyphenols
(2007)Surfactant protein-A (SP-A) is the best studied and most abundant of the protein components of lung surfactant and plays an important role in host defense of the lung. It has been shown that ozone-induced oxidation of SP-A ... -
Inhibition of the Na-H + exchanger isoform-1 and the extracellular signal-regulated kinase induces apoptosis: A time course of events
(2006)Aims: The present study attempts to shed light on the role and the relative position of the Na +/H + exchanger isoform 1 (NHE1) and the extracellular signal-regulated kinase (ERK) in HEp-2 cell signaling pathways concerning ... -
Insights on the impact of deep eutectic solvents on the composition of the extracts from lemon (Citrus limon L.) peels analyzed by a novel RP-LC–QTOF-MS/MS method
(2022)Extraction of polyphenolic compounds from lemon peels using deep eutectic solvents (DES) was investigated. A choline chloride-based DES paired with glycerol was used as the extraction solvent, alternative to conventional ... -
Morphological, nutritional and chemical description of "Vatikiotiko", an onion local landrace from Greece
(2015)"Vatikiotiko" is an onion local landrace from Greece with special quality features, such as strong and pungent taste and storability. In this study, we tried for the first time to describe this landrace and record its ... -
Natural flavonoids as antidiabetic agents. The binding of gallic and ellagic acids to glycogen phosphorylase b
(2015)We present a study on the binding of gallic acid and its dimer ellagic acid to glycogen phosphorylase (GP). Ellagic acid is a potent inhibitor with K(i)s of 13.4 and 7.5 mu M, in contrast to gallic acid which displays K(i)s ... -
Natural products and their derivatives as inhibitors of glycogen phosphorylase: potential treatment for type 2 diabetes
(2014)Glycogen phosphorylase (GP) (EC 2.4.1.1) is an important therapeutic target for the potential treatment of type 2 diabetes. The search for potent, selective and drug-like GP inhibitors which may eventually lead to hypoglycaemic ... -
Optimization of the vacuum microwave assisted extraction of the natural polyphenols and flavonoids from the raw solid waste of the pomegranate juice producing industry at industrial scale
(2021)Pomegranate pomace (PP) is the solid waste produced in bulk by the pomegranate juice industry which is rich in polyphenols and flavonoids that can replace the hazardous chemical antioxidants/antimicrobials currently used ... -
Prospective comparative study evaluating the role of flavonoids after endovenous thermal ablation
(2021)Objectives: The aim of our study was to evaluate the role of flavonoids in the improvement of post-operative symptoms after endovenous thermal ablation (EVTA). Methods: A prospective comparative study of 120 consecutive ... -
The role of flavonoids in inhibiting Th17 responses in inflammatory arthritis
(2018)Flavonoids have been considered powerful anti-inflammatory agents, and their exact immunomodulatory action as therapeutic agents in autoimmune diseases has started to emerge. Their role in the manipulation of immunoregulation ... -
Seasonal variation in bioactive properties and phenolic composition of cardoon (Cynara cardunculus var. altilis) bracts
(2021)Cardoon (Cynara cardunculus L.) bracts were collected at different maturation stages to investigate seasonal changes in the phenolic compounds profile and in vitro bioactivities. Among the 12 phenolic compounds tentatively ...