Browsing by Subject "catalase"

17-β estradiol attenuates the pro-oxidant activity of corticotropin-releasing hormone in macroendothelial cells

Filiponi M., Gougoura S.G., Befani C., Bargiota Α., Liakos P., Koukoulis G.N. (2019)

Corticotropin-releasing hormone, which is the predominant regulator of neuroendocrine responses to stress, attenuates inflammation through stimulation of glucocorticoid release. Enhanced corticotropin-releasing hormone ...

Administration of exercise-conditioned plasma alters muscle catalase kinetics in rat: An argument for in vivo-like Km instead of in vitro-like Vmax

Veskoukis A.S., Paschalis V., Kyparos A., Nikolaidis M.G. (2018)

Maximal velocity (Vmax) is a well established biomarker for the assessment of tissue redox status. There is scarce evidence, though, that it does not probably reflect sufficiently in vivo tissue redox profile. Instead, the ...

Antioxidant responses following active and passive smoking of tobacco and electronic cigarettes

Poulianiti K., Karatzaferi C., Flouris A.D., Fatouros I.G., Koutedakis Y., Jamurtas A.Z. (2016)

Context: It has been indicated that acute active and passive tobacco cigarette smoking may cause changes on redox status balance that may result in significant pathologies. However, no study has evaluated the effects of ...

Assessment of the redox status in patients with metabolic syndrome and type 2 diabetes reveals great variations

Spanidis Y., Mpesios A., Stagos D., Goutzourelas N., Bar-Or D., Karapetsa M., Zakynthinos E., Spandidos D.A., Tsatsakis A.M., Leon G., Kouretas D. (2016)

The aim of the present study was to examine the effectiveness of a new redox status marker, the static oxidation reduction potential (sORP), for assessing oxidative stress in 75 patients with metabolic syndrome (MetS) and ...

A battery of translational biomarkers for the assessment of the in vitro and in vivo antioxidant action of plant polyphenolic compounds: The biomarker issue

Veskoukis A., Kerasioti E., Priftis A., Kouka P., Spanidis Y., Makri S., Kouretas D. (2019)

Over the last decades, the scientific findings stressing the beneficial health implications of plant-derived compounds (i.e., plant extracts rich in polyphenols) have been increased significantly. Assessing the properties ...

Buprenorphine and Methadone as Opioid Maintenance Treatments for Heroin-Addicted Patients Induce Oxidative Stress in Blood

Leventelis C., Goutzourelas N., Kortsinidou A., Spanidis Y., Toulia G., Kampitsi A., Tsitsimpikou C., Stagos D., Veskoukis A.S., Kouretas D. (2019)

Buprenorphine and methadone are two substances widely used in the substitution treatment of patients who are addicted to opioids. Although it is known that they partly act efficiently towards this direction, there is no ...

Cardiotoxicity in rabbits after long-term nandrolone decanoate administration

Vasilaki F., Tsitsimpikou C., Tsarouhas K., Germanakis I., Tzardi M., Kavvalakis M., Ozcagli E., Kouretas D., Tsatsakis A.M. (2016)

Abuse of anabolic androgenic steroids is linked to a variety of cardiovascular complications. The aim of our study was to investigate the possible cardiovascular effects of nandrolone decanoate on young rabbits using ...

Cardiotoxicity of Chemical Substances: An Emerging Hazard Class

Georgiadis N., Tsarouhas K., Dorne J.-L.C.M., Kass G.E.N., Laspa P., Toutouzas K., Koulaouzidou E.A., Kouretas D., Tsitsimpikou C. (2022)

(1) Background: Human health risks and hazards from chemical substances are well regulated internationally. However, cardiotoxicity, is not defined as a stand-alone hazard and therefore there are no defined criteria for ...

The combined and single effect of salinity and copper stress on growth and quality of Mentha spicata plants

Chrysargyris A., Papakyriakou E., Petropoulos S.A., Tzortzakis N. (2019)

Copper is essential for plant growth, but in excess may cause adverse effects on plant physiology. Harmful effects are also caused by plant exposure to salinity (NaCl) due to the excessive use of fertilizers, soil degradation ...

Correlation between intermediary metabolism, Hsp gene expression, and oxidative stress-related proteins in long-term thermal-stressed Mytilus galloprovincialis

Feidantsis K., Giantsis I.A., Vratsistas A., Makri S., Pappa A.-Z., Drosopoulou E., Anestis A., Mavridou E., Exadactylos A., Vafidis D., Michaelidis B. (2020)

Long-term exposure of Mytilus galloprovincialis to temperatures beyond 26°C triggers mussel mortality. The present study aimed to integratively illustrate the correlation between intermediary metabolism, hsp gene expression, ...

Dose-response effects of high-intensity interval neuromuscular exercise training on weight loss, performance, health and quality of life in inactive obese adults: Study rationale, design and methods of the DoIT trial

Batrakoulis A., Fatouros I.G., Chatzinikolaou A., Draganidis D., Georgakouli K., Papanikolaou K., Deli C.K., Tsimeas P., Avloniti A., Syrou N., Jamurtas A.Z. (2019)

Obesity is associated with high mortality and morbidity rates and low levels of quality of life among adults globally. It is critical to examine evidence-based practices for developing lifestyle behavioral changes such as ...

Downgrading the systemic condition of rabbits after long term exposure to cypermethrin and piperonyl butoxide

Vardavas A.I., Fragkiadaki P., Alegakis A.K., Dimitrios K., Goutzourelas N., Tsiaoussis J., Tsitsimpikou C., Stivaktakis P.D., Carvalho F., Tsatsakis A.M. (2016)

Aim The aim of this study is to clarify the effect of cypermethrin (CY) on the oxidative stress (OS) and inflammation status of animals exposed to it and the synergistic role of piperonyl butoxide (PB0). Main methods Markers ...

Effect of CRH on NO bioavailability, ROS production and antioxidant defense systems in endothelial EAhy926 cells

Gougoura, S.; Liakos, P.; Koukoulis, G. N. (2010)

Local or 'Immune' Corticotropin-Releasing Hormone (CRH) is secreted in peripheral tissues and plays a direct immunomodulatory role as an endocrine or paracrine mediator of inflammation. The present study was undertaken to ...

The Effect of Physical Exercise on Oxidation Capacity and Utero-Placental Circulation in Pregnancies with Gestational Diabetes Mellitus and Uncomplicated Pregnancies, a Pilot Study

Chatzakis C., Sotiriadis A., Fatouros I.G., Jamurtas A.Z., Deli C.K., Papagianni M., Dinas K., Mastorakos G. (2022)

Background: Gestational diabetes mellitus (GDM) is associated with aggravated oxidation capacity and utero-placental circulation, while aerobic exercise could improve both. The study aims to assess oxidation capacity and ...

Effects of acute exercise on liver function and blood redox status in heavy drinkers

Georgakouli K., Manthou E., Fatouros I.G., Deli C.K., Spandidos D.A., Tsatsakis A.M., Kouretas D., Koutedakis Y., Theodorakis Y., Jamurtas A.Z. (2015)

Excessive alcohol consumption can induce oxidative stress, resulting in the development of several diseases. Exercise has been reported to prevent and/or improve a number of health issues through several mechanisms, including ...

The effects of acute low-volume HIIT and aerobic exercise on leukocyte count and redox status

Jamurtas A.Z., Fatouros I.G., Deli C.K., Georgakouli K., Poulios A., Draganidis D., Papanikolaou K., Tsimeas P., Chatzinikolaou A., Avloniti A., Tsiokanos A., Koutedakis Y. (2018)

A single bout of exercise can result in inflammatory responses, increased oxidative stress and upregulation of enzymatic antioxidant mechanisms. Although low-volume high-intensity interval training (HIIT) has become popular, ...

Effects of combined administration of doxorubicin and chloroquine on lung pathology in mice with solid Ehrlich ascites carcinoma

Utkusavas A., Gurel Gurevin E., Yilmazer N., Uvez A., Oztay F., Bulut H., Ustunova S., Esener O.B.B., Sonmez K., Erol Kutucu D., Meral I., Dimas K., Armutak E.I. (2022)

Combined use of a chemotherapeutic agent and an autophagy inhibitor is a novel cancer treatment strategy. We investigated the effects of chloroquine (CQ) on lung pathology caused by both solid Ehrlich ascites carcinoma ...