Browsing by Subject "STEM-CELLS"
Now showing items 1-9 of 9
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Autoimmune hepatitis type 1 and primary biliary cirrhosis have distinct bone marrow cytokine production
(2005)We have recently reported differences in the hematopoiesis between autoimmune hepatitis type I (AIH-1) and primary biliary cirrhosis (PBC). In view of the notion that cytokines are regulators of hematopoiesis, we investigated ... -
beta 4 Integrin Marks Interstitial Myogenic Progenitor Cells in Adult Murine Skeletal Muscle
(2012)Skeletal muscle growth and its regeneration following injury rely on myogenic progenitor cells, a heterogeneous population that includes the satellite cells and other interstitial progenitors. The present study demonstrates ... -
Connexin43 and Connexin47 Alterations after Neural Precursor Cells Transplantation in Experimental Autoimmune Encephalomyelitis
(2015)Exogenous transplanted neural precursor cells (NPCs) exhibit miscellaneous immune-modulatory effects in models of autoimmune demyelination. However, the regional interactions of NPCs with the host brain tissue in remissive ... -
Hemopoietic progenitor cells and bone marrow stromal cells in patients with autoimmune hepatitis type 1 and primary biliary cirrhosis
(2003)Background/Aims: Autologous hematopoietic stem cell transplantation has been used in severe cases of autoimmunity. We investigated whether hemopoietic progenitor cells and/or bone marrow (BM) microenvironment are affected ... -
Implications of pleiotrophin in human PC3 prostate cancer cell growth in vivo
(2012)Pleiotrophin (PTN) is a heparin-binding growth factor with diverse functions related to tumor growth, angiogenesis, and metastasis. Pleiotrophin seems to have a significant role in prostate cancer cell growth and to mediate ... -
Mechanisms of proteasome inhibitor-induced cytotoxicity in malignant glioma
(2013)The 26S proteasome constitutes an essential degradation apparatus involved in the consistent recycling of misfolded and damaged proteins inside cells. The aberrant activation of the proteasome has been widely observed in ... -
Neuroblastoma cells negative for CD44 possess tumor-initiating properties
(2011)CD44 has been linked to favorable prognosis in neuroblastoma and in the present study we investigate if it can be used to prospectively isolate neuroblastoma-initiating cells. To define the cancer-initiating properties of ... -
Oxidative stress due to radiation in CD34(+) Hematopoietic progenitor cells: protection by IGF-1
(2012)Radiation exerts direct as well as indirect effects on DNA through the generation of reactive oxygen species (ROS). Irradiated hematopoietic progenitor cells (HPCs) experience DNA strand breaks, favoring genetic instability, ... -
The past, present and future in scaffold-based tendon treatments
(2015)Tendon injuries represent a significant clinical burden on healthcare systems worldwide. As the human population ages and the life expectancy increases, tendon injuries will become more prevalent especially among young ...