Πλοήγηση ανά Συγγραφέα "Oikonomou, P."
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Association of interleukin-1A, interleukin-1B and interleukin-1 receptor antagonist gene polymorphisms with multiple myeloma
Abazis-Stamboulieh, D.; Oikonomou, P.; Papadoulis, N.; Panayiotidis, P.; Vrakidou, E.; Tsezou, A. (2007)Interleukin-1 (IL-1) is a cytokine involved in the maturation and proliferation of B cells and plays a significant role in the development of lytic bone lesions, a major clinical feature of multiple myeloma (MM) patients. ... -
Bagged nonlinear Hebbian learning algorithm for fuzzy cognitive maps working on classification tasks
Papageorgiou, E. I.; Oikonomou, P.; Kannappan, A. (2012)Learning of fuzzy cognitive maps (FCMs) is one of the most useful characteristics which have a high impact on modeling and inference capabilities of them. The learning approaches for FCMs are concentrated on learning the ... -
The Catabolic Role of Toll-Like Receptor 2 (TLR-2) Mediated by the NF-kappa B Pathway in Septic Arthritis
Papathanasiou, I.; Malizos, K. N.; Poultsides, L.; Karachalios, T.; Oikonomou, P.; Tsezou, A. (2011)Toll-like receptors (TLRs) are involved in mediating cell activation on stimulation with microbial components. Our objective was to investigate the role of 'PLR-2 mediated by the NF-kappa B pathway in septic arthritic ... -
Central Role of SREBP-2 in the Pathogenesis of Osteoarthritis
Kostopoulou, F.; Gkretsi, V.; Malizos, K. N.; Iliopoulos, D.; Oikonomou, P.; Poultsides, L.; Tsezou, A. (2012)Background: Recent studies have implied that osteoarthritis (OA) is a metabolic disease linked to deregulation of genes involved in lipid metabolism and cholesterol efflux. Sterol Regulatory Element Binding Proteins (SREBPs) ... -
Correlation of promoter hypermethylation in hTERT, DAPK and MGMT genes with cervical oncogenesis progression
Iliopoulos, D.; Oikonomou, P.; Messinis, I.; Tsezou, A. (2009)DNA hypermethylation occurs during the multi-step process of cervical carcinogenesis. We investigated whether the methylation status in the promoter region of a potential oncogene, the human telomerase reverse transcriptase ... -
DNA methylation is not likely to be responsible for hTERT expression in premalignant cervical lesions
Oikonomou, P.; Messinis, I.; Tsezou, A. (2007)Human telomerase reverse transcriptase (hTERT) MRNA expression seems to play an important role in cervical carcinogenesis. Analysis of the hTERT promoter region revealed the presence of a CpG island and a high overall GC ... -
The growth differentiation factor 5 (GDF5) core promoter polymorphism is not associated with knee osteoarthritis in the Greek population
Tsezou, A.; Satra, M.; Oikonomou, P.; Bargiotas, K.; Malizos, K. N. (2008)Genetic factors have been shown to play an important role in the etiology of osteoarthritis (OA). A functional single nucleotide polymorphism (SNP) +104T/C; rs143383 in the 5' UTR of the GDF5 gene was recently associated ... -
Integrative MicroRNA and Proteomic Approaches Identify Novel Osteoarthritis Genes and Their Collaborative Metabolic and Inflammatory Networks
Iliopoulos, D.; Malizos, K. N.; Oikonomou, P.; Tsezou, A. (2008)Background: Osteoarthritis is a multifactorial disease characterized by destruction of the articular cartilage due to genetic, mechanical and environmental components affecting more than 100 million individuals all over ... -
Particle Swarm Optimization approach for fuzzy cognitive maps applied to autism classification
Oikonomou, P.; Papageorgiou, E. I. (2013)The task of classification using intelligent methods and learning algorithms is a difficult task leading the research community on finding new classifications techniques to solve it. In this work, a new approach based on ... -
Quantitative determination of human telomerase reverse transcriptase messenger RNA expression in prematignant cervical lesions and correlation with human papittomavirus load
Oikonomou, P.; Mademtzis, I.; Messinis, I.; Tsezou, A. (2006)Expression Of human telomerase reverse transcriptase (hTERT) messenger RNA (mRNA) and human papillomavirus (HPV)-16 load were quantified using real-time polymerase chain reaction and correlated with cytological findings ... -
The role of human telomerase catalytic subunit mRNA expression in cervical dysplasias
Tsezou, A.; Oikonomou, P.; Kollia, P.; Mademtzis, I.; Kostopoulou, E.; Messinis, I.; Vamvakopoulos, N. (2005)Telomerase activity and human telomerase reverse transcriptase (hTERT) mRNA expression were investigated in cervical specimens and were correlated with cytologic findings and the presence of human papilloma virus (HPV) ... -
Use of real-time PCR to detect human papillomavirus-16 viral loads in vaginal and urine self-sampled specimens
Daponte, A.; Tsezou, A.; Oikonomou, P.; Hadjichristodoulou, C.; Maniatis, A. N.; Pournaras, S.; Messinis, I. E. (2008)Increasing the accuracy of self-sampling methods to detect oncogenic human papillomavirus (HPV) infection would contribute to the wider application of these approaches. In this study, 120 women were tested for HPV-16 by ...