Πλοήγηση ανά Συγγραφέα "Kouvaras, E."
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Acute in vivo exposure to fentanyl reduces GABA immunoreactivity in the CA1 area of the rat hippocampus
Kouvaras, E.; Kilindris, T.; Vasilaki, A.; Asprodini, E. K. (2008)The effect of in vivo fentanyl treatment on GABAergic immunoreactivity was studied in the CA1 area of the rat hippocampus. Animals were treated either with saline or fentanyl (4x80 μg/kg, s.c./15min). GABA immunohistochemistry ... -
Anaplastic lymphoma kinase-positive diffuse large B cell lymphoma: Immunohistochemical and FISH analysis of a rare tumor with unusual clinical presentation
Ioannou, M. G.; Kouvaras, E.; Panagiotidis, P.; Papamichali, R.; Papacharalambous, C.; Koukoulis, G. K.; Androulaki, A. (2013)Anaplastic lymphoma kinase-positive diffuse large B cell lymphoma represents a distinct subtype of diffuse large B cell lymphoma with a characteristic morphology, a distinct immunophenotypic profile, and recurrent ... -
Aurora B kinase in Hodgkin lymphoma: immunohistochemical pattern of expression in neoplastic Hodgkin and Reed-Sternberg cells
Ioannou, M.; Kouvaras, E.; Stathakis, E.; Samara, M.; Koukoulis, G. K. (2014)Aurora B is a member of the chromosomal passenger complex, which is essential for proper completion of mitosis and cell division (cytokinesis). Inappropriate chromosomal segregation and cytokinesis due to deregulated ... -
Comparative study of spatial localization of HER-2 and CEP17 signals and of HER-2/CEP17 ratios, in "thin" and "thick" tissue sections
Kouvaras, E.; Papandreou, C. N.; Daliani, D. D.; Athanasiadis, A.; Koukoulis, G. K. (2012)One presumed drawback of performing fluorescence in situ hybridization on routine tissue sections for HER-2 status evaluation in breast carcinomas is nuclear truncation. Therefore, HER-2/CEP 17 ratios were compared in ... -
Development and validation of a reversed-phase HPLC method for CYP1A2 phenotyping by use of a caffeine metabolite ratio in saliva
Begas, E.; Kouvaras, E.; Tsakalof, A. K.; Bounitsi, M.; Asprodini, E. K. (2015)CYP1A2 is important for metabolizing various clinically used drugs. Phenotyping of CYP1A2 may prove helpful for drug individualization therapy. Several HPLC methods have been developed for quantification of caffeine ... -
Differential expression of NMDA and AMPA receptor subunits in rat dorsal and ventral hippocampus
Pandis, C.; Sotiriou, E.; Kouvaras, E.; Asprodini, E.; Papatheodoropoulos, C.; Angelatou, F. (2006)Several studies have demonstrated anatomical and functional segregation along the dorsoventral axis of the hippocampus. This study examined the possible differences in the AMPA and NMDA receptor subunit composition and ... -
Evaluation of Current Prognostic and Predictive Markers in Breast Cancer: A Validation Study of Tissue Microarrays
Batistatou, A.; Televantou, D.; Bobos, M.; Eleftheraki, A. G.; Kouvaras, E.; Chrisafi, S.; Koukoulis, G. K.; Malamou-Mitsi, V.; Fountzilas, G. (2013)Background: Tissue microarrays (TMAs) are an attractive alternative to analysis of whole sections (WS). For breast carcinomas, the recent recommendations for cut-offs (i.e. Ki67, H-score) have necessitated the re-evaluation ... -
Fentanyl treatment reduces GABAergic inhibition in the CA1 area of the hippocampus 24 h after acute exposure to the drug
Kouvaras, E.; Asprodini, E. K.; Asouchidou, I.; Vasilaki, A.; Kilindris, T.; Michaloudis, D.; Koukoutianou, I.; Papatheodoropoulos, C.; Kostopoulos, G. (2008)The effect of in vivo fentanyl treatment on synaptic transmission was studied in the CA1 area of the rat hippocampus. Animals were treated either with saline or fentanyl (4 x 80 mu g/kg, s.c./15 min). Intracellular in vitro ... -
Hypoxia Inducible Factor-1alpha and Vascular Endothelial Growth Factor in Biopsies of Small Cell Lung Carcinoma
Ioannou, M.; Papamichali, R.; Kouvaras, E.; Mylonis, I.; Vageli, D.; Kerenidou, T.; Barbanis, S.; Daponte, A.; Simos, G.; Gourgoulianis, K.; Koukoulis, G. K. (2009)Neoangiogenesis has been documented in small cell lung carcinoma (SCLC). In addition, antiangiogenic therapies are being tested in clinical trials that involve SCLC. However, study of the underlying mechanisms has been ... -
In vivo evaluation of CUP1A2 and CYP2A6 activities in a Greek population during menopause
Begas, E.; Kouvaras, E.; Tsiokou, V.; Asprodini, E. K. (2008)Human CYP enzyme system is involved in the metabolism of various endogenous compounds. Previous studies have shown that CYP activity is influenced by age and gender. In the present study caffeine metabolites were used for ... -
In vivo evaluation of CYP1A2 CYP2A6, NAT-2 and xanthine oxidase activities in a Greek population sample by the RP-HPLC monitoring of caffeine metabolic ratios
Begas, E.; Kouvaras, E.; Tsakalof, A.; Papakosta, S.; Asprodini, E. K. (2007)A RP-HPLC method was developed for the assessment of caffeine and its metabolites in urine and was used for the evaluation of the CYP1A2, CYP2A6, xanthine oxidase (XO) and N-acetyl-transferase-2 (NAT-2) in vivo activities ... -
INCENP (Inner Centromere Protein) is Overexpressed in High Grade Non-Hodgkin B-cell Lymphomas
Barbanis, S.; Ioannou, M.; Kouvaras, E.; Karasavvidou, F.; Nakou, M.; Papamichali, R.; Koukoulis, G. (2009)Inner centromere protein (INCENP) is a member of the Chromosomal Passenger Complex (CPC), which is a four member protein complex essential for proper completion of mitosis and cell division (cytokinesis). Inappropriate ... -
Increased HIF-1 alpha immunostaining in psoriasis compared to psoriasiform dermatitides
Ioannou, M.; Sourli, F.; Mylonis, I.; Barbanis, S.; Papamichali, R.; Kouvaras, E.; Zafiriou, E.; Siomou, P.; Klimi, E.; Simos, G.; Roussaki-Schulze, A. V.; Koukoulis, G. (2009)Background Expression of hypoxia inducible factor 1 (HIF-1) alpha can be linked to inflammation through reciprocal interactions with several cytokines. This finding is in accordance with the previously noted HIF-1 alpha ... -
Ketamine Reverses the Fentanyl-induced Increase in NMDA-mediated Synaptic Transmission in CA1 Area of the Rat Hippocampus
Kouvaras, E.; Asouchidou, E.; Michaloudis, D.; Sakellaridis, N.; Asprodini, E. (2004) -
Myxoid liposarcoma with cartilaginous differentiation: A case study with fish analysis and review of the literature
G.Ioannou, M.; Kouvaras, E.; Papamichali, R.; Karachalios, T.; Koukoulis, G. (2013)Cartilaginous differentiation is rarely encountered in myxoid liposarcomas. To date, a small number of such cases have been described, and molecular or cytogenetic analysis was performed only in few of them. In the present ... -
Nodular lymphocyte-predominant Hodgkin lymphoma of the tonsil: A case study using immunohistochemistry and FISH analysis and review of the literature
Ioannou, M. G.; Kouvaras, E.; Gletsou, E.; Papacharalambous, C.; Matsouka, P.; Koukoulis, G. K.; van der Walt, J. D. (2011)Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is a rare subtype of Hodgkin lymphoma that differs from classic Hodgkin lymphoma with respect to histological and clinical presentations. This type of lymphoma typically ... -
Prevention of postoperative adhesion formation by individual and combined administration of 4 per cent icodextrin and dimetindene maleate
Tepetes, K.; Asprodini, E. K.; Christodoulidis, G.; Spyridakis, M.; Kouvaras, E.; Hatzitheofilou, K. (2009)Background, To date, no single method has been successful in eliminating peritoneal adhesion formation after major abdominal surgery. This study evaluated the individual and possible synergistic effect of a local intraperitoneal ... -
A single exposure to μ-opioid receptor agonist fentanyl in vivo is sufficient to induce long-term reduction in GABA-mediated synaptic transmission recorded from hippocampal CA1 pyramidal neurons in an in vitro slice preparation
Kouvaras, E.; Asouchidou, E.; Michaloudis, D.; Asprodini, E. (2006) -
Validated analysis of HIF-1 alpha expression in cancer cells using a controlled and comparative immunoassay
Ioannou, M.; Mylonis, I.; Kouvaras, E.; Papamichali, R.; Daponte, A.; Paraskeva, E.; Simos, G.; Koukoulis, G. K. (2010)The immunoreactivity of hypoxia inducible factor 1 alpha (HIF-1 alpha) has been considered a reliable indicator of the HIF-1 pathway activation in tissue hypoxia. However, HIF-1 alpha immunoreactivity has been evaluated ... -
Validated analysis of HIF-1α expression in cancer cells using a controlled and comparative immunoassay
Ioannou, M.; Mylonis, I.; Kouvaras, E.; Papamichali, R.; Daponte, A.; Paraskeva, E.; Simos, G.; Koukoulis, G. K. (2010)The immunoreactivity of hypoxia inducible factor 1 α (HIF-1α) has been considered a reliable indicator of the HIF-1 pathway activation in tissue hypoxia. However, HIF-1α immunoreactivity has been evaluated with different ...