Πλοήγηση ανά Θέμα "rat"
Αποτελέσματα 21-40 από 77
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Do β3-adrenoceptor agonists cause urinary bladder smooth muscle relaxation by inhibiting acetylcholine release?
(2017)[No abstract available] -
The effect of allopurinol on protein carbonyls and swimming performance in rats
(2008)Allopurinol is an inhibitor of xanthine oxidase. Xanthine oxidase is a major contributor of free radicals during exercise. Previous studies have shown that free radicals are vital for physiological adaptations in exercise. ... -
Effect of somatostatinergic analogues on the ischemia-induced release of [3H]-D-aspartate and [3H]-GABA from rat retina and hippocampus
(2008)The modulation of the enhanced release of [3H]-D-Aspartate and [3H]GABA following ischemia-like conditions was studied in rat retinal and hippocampal preparations using a superfusion system. Ischemia was simulated by a ... -
Effects of Anesthetic Ketamine on Anxiety-Like Behaviour in Rats
(2019)There is scarce information regarding the effects of anesthetic doses of the non-competitive N-methyl-d-aspartate receptor antagonist ketamine on anxiety. The current study evaluated the acute effects of intraperitoneally ... -
Effects of low doses of different nitric oxide (NO) donors in rat models of obsessive-compulsive disorder (OCD) and posttraumatic stress disorder (PTSD)
(2022)Several lines of evidence suggest that the intra- and inter-cellular messenger nitric oxide (NO) is critically involved in anxiety. Contrasting findings are reported, however, regarding the effects of NO donors in preclinical ... -
Effects of scopolamine and L-NAME on rats' performance in the object location test
(2007)The object location task is a new procedure evaluating spatial memory abilities in the rat. The aim of the present study was to characterize this behavioural paradigm by pharmacologic means. For this purpose, the effects ... -
Effects of sheep/goat whey protein dietary supplementation on the redox status of rats
(2018)The purpose of the present study is to estimate the effects of sheep/goat whey protein dietary supplementation on the redox status of blood and tissues of rats. Twelve male Wistar rats were divided into the control group ... -
Effects of sub-anesthetic doses of ketamine on rats' spatial and non-spatial recognition memory
(2008)There are experimental evidences indicating that the non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist ketamine impairs cognition and produces a series of schizophrenia-like symptoms in rodents (hyperactivity, ... -
Effects of the active constituents of Crocus sativus L. crocins and their combination with memantine on recognition memory in rats
(2018)Crocus sativus L., is a plant cultivated in many countries of the world. Crocins are among the active constituents of C. sativus and their implication in cognition has been proposed. The present study was designed to ... -
Effects of the inducible nitric oxide synthase inhibitor aminoguanidine in two different rat models of schizophrenia
(2016)Several lines evidence indicate that the non-competitive N-methyl-d-aspartate (NMDA) receptor antagonist ketamine and the mixed dopamine (DA) D1/D2 receptor agonist apomorphine induce schizophrenia-like symptoms in rodents, ... -
Effects of the Nitric Oxide Synthase Inhibitor L-NAME on Recognition and Spatial Memory Deficits Produced by Different NMDA Receptor Antagonists in the Rat
(2010)There is consistent experimental evidence that noncompetitive antagonists of the N-methyl-D-aspartate (NMDA) receptor, such as ketamine, MK-801, and phencyclidine (PCP), impair cognition and produce psychotomimetic effects ... -
Enhancer of rudimentary homologue interacts with scaffold attachment factor B at the nuclear matrix to regulate SR protein phosphorylation
(2017)Scaffold attachment factor B1 (SAFB1) is an integral component of the nuclear matrix of vertebrate cells. It binds to DNA on scaffold/matrix attachment region elements, as well as to RNA and a multitude of different proteins, ... -
Experimental Cardiac Hypertrophy Induced by Oral Administration of Mineralocorticoid and Saline in Rats
(2012)We suggest a new, easily applicable way of myocardial hypertrophy induction in rats. Forty randomized age-matched male Wistar rats were divided into 2 groups of 20 each: a control group and an orally administered ... -
Feeding behavior during long-term hexarelin administration in young and old rats
(2008)Ghrelin, a 28-amino-acid peptide isolated from the stomach, is the natural ligand of the GH-secretagogues receptor-la (GHS-R1a) and, so far, the only discovered circulating appetite-stimulating hormone. Similarly to ghrelin, ... -
Flumazenil but not bicuculline counteract the impairing effects of anesthetic ketamine on recognition memory in rats. Evidence for a functional interaction between the GABA A -benzodiazepine receptor and ketamine?
(2019)Experimental evidence indicates that anesthetic doses of the non-competitive NMDA receptor antagonist ketamine impair memory abilities in rodents. The mechanism by which anesthetic ketamine produces its adverse behavioural ... -
The gabaa-benzodiazepine receptor antagonist flumazenil abolishes the anxiolytic effects of the active constituents of crocus sativus l. Crocins in rats
(2020)Anxiety is a chronic severe psychiatric disorder. Crocins are among the various bioactive components of the plant Crocus sativus L. (Iridaceae) and their implication in anxiety is well-documented. However, which is the ... -
Heroin-induced changes of catecholamine-containing particles in male rat cerebellar cortex
(2001)The content and distribution of catecholamine-containing formations in the cerebellum of untreated and heroin-treated male rats, was visualized by glyoxylic acid-induced histofluorescence, in an attempt to define the ... -
Hypothalamic inflammation as a potential pathophysiologic basis for the heterogeneity of clinical, hormonal, and metabolic presentation in pcos
(2021)Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age. It is a heterogeneous condition characterized by reproductive, endocrine, metabolic, and psychiatric abnormalities. ... -
Intra-Abdominal Hypertension Causes Bacterial Growth in Lungs: An Animal Study
(2017)To study the effect of intra-abdominal hypertension (IAH) on the frequency of pneumonia with an experimental study, thirteen Sprague-Dawley rats were included. Eight out of thirteen animals were randomly assigned to receive ... -
Ketamine disrupted storage but not retrieval of information in male rats and apomorphine counteracted its impairing effect
(2020)Ketamine, a non-competitive NMDA receptor antagonist, has been reported to mimic the cognitive symptoms of schizophrenia in animals. It has been reported to produce learning and memory deficits in rodents. However, there ...