• Sarcopenia: From definition to treatment 

      Dionyssiotis Y., Kapsokoulou A., Samlidi E., Angoules A.G., Papathanasiou J., Chronopoulos E., Kostoglou-Athanassiou I., Trovas G. (2017)
      [No abstract available]
    • Specific inhibition of hif activity: Can peptides lead the way? 

      Mylonis I., Chachami G., Simos G. (2021)
      Reduced oxygen availability (hypoxia) is a characteristic of many disorders including cancer. Central components of the systemic and cellular response to hypoxia are the Hypoxia Inducible Factors (HIFs), a small family of ...
    • A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression 

      Verginadis I.I., Avgousti H., Monslow J., Skoufos G., Chinga F., Kim K., Leli N.M., Karagounis I.V., Bell B.I., Velalopoulou A., Salinas C.S., Wu V.S., Li Y., Ye J., Scott D.A., Osterman A.L., Sengupta A., Weljie A., Huang M., Zhang D., Fan Y., Radaelli E., Tobias J.W., Rambow F., Karras P., Marine J.-C., Xu X., Hatzigeorgiou A.G., Ryeom S., Diehl J.A., Fuchs S.Y., Puré E., Koumenis C. (2022)
      Bidirectional signalling between the tumour and stroma shapes tumour aggressiveness and metastasis. ATF4 is a major effector of the Integrated Stress Response, a homeostatic mechanism that couples cell growth and survival ...
    • Triazole double-headed ribonucleosides as inhibitors of eosinophil derived neurotoxin 

      Chatzileontiadou D.S.M., Parmenopoulou V., Manta S., Kantsadi A.L., Kylindri P., Griniezaki M., Kontopoulou F., Telopoulou A., Prokova H., Panagopoulos D., Boix E., Balatsos N.A.A., Komiotis D., Leonidas D.D. (2015)
      Eosinophil derived neurotoxin (EDN) is an eosinophil secretion protein and a member of the Ribonuclease A (RNase A) superfamily involved in the immune response system and inflammatory disorders. The pathological actions ...