Listar por tema "animal model"
Mostrando ítems 21-40 de 141
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Cardiotoxicity in rabbits after long-term nandrolone decanoate administration
(2016)Abuse of anabolic androgenic steroids is linked to a variety of cardiovascular complications. The aim of our study was to investigate the possible cardiovascular effects of nandrolone decanoate on young rabbits using ... -
Chimeric stimuli-responsive liposomes as nanocarriers for the delivery of the anti-glioma agent TRAM-34
(2021)Nanocarriers are delivery platforms of drugs, peptides, nucleic acids and other therapeutic molecules that are indicated for severe human diseases. Gliomas are the most frequent type of brain tumor, with glioblastoma being ... -
Clinical, ultrasonographic and pathological features following unilateral vasectomy in rams
(2008)The effects of vasectomy on testes and related structures of animal species and men are largely disputable. These possible effects were studied in the ram, an established experimental animal model used to investigate ... -
Continuous chest compressions with asynchronous ventilation improve survival in a neonatal swine model of asphyxial cardiac arrest
(2021)Background: Guidelines for neonatal resuscitation recommend a 3:1 compression to ventilation ratio. However, this recommendation is based on expert opinion and consensus rather than strong scientific evidence. Our primary ... -
Contrast-induced nephropathy in an animal model: Evaluation of novel biomarkers in blood and tissue samples
(2019)Identification of novel biomarkers of contrast-induced nephropathy (CIN)that may more accurately detect renal function changes; reflect kidney damage; assist monitoring; and elucidate pathophysiology attract considerable ... -
The contribution of a collagen patch coated with fibrin glue in sealing upper gastrointestinal defects: An experimental study
(2021)Background/Aim: We aimed to evaluate the safety and efficacy of sealing primary upper gastrointestinal (GI) perforations with a collagen patch coated with fibrin glue (Tachosil®). Materials and Methods: Thirty New Zealand ... -
Control of swine enzootic pneumonia by spraying organic acids in fatteners' buildings [Έλεγχος της ενξωοτικής πνευμονίας σε παχυνόμενους χοίρους με ψεκασμό μείγματος οργανικών οξέων στα παχυντήρια των χοιροστασίων]
(2018)In this study, the possibility to control enzootic pneumonia by spraying mild organic acids in fatteners' buildings was investigated. In a farm with enzootic pneumonia, two groups, each of 120 weaned pigs, were housed in ... -
A controlled trial of polyglytone 6211 versus poliglecaprone 25 for use in intradermal suturing in dogs
(2021)The objective of this work was the comparative evaluation of the healing process after em-ploying 4/0 poliglecaprone 25 and 4/0 polyglytone 6211 in a continuous intradermal suture pattern. Ten Beagle dogs were used, in ... -
Deficiency of the B cell-activating factor receptor results in limited CD169+ macrophage function during viral infection
(2015)The B cell-activating factor (BAFF) is critical for B cell development and humoral immunity in mice and humans. While the role of BAFF in B cells has been widely described, its role in innate immunity remains unknown. Using ... -
Detection of cathelicidin-1 in the milk as an early indicator of mastitis in ewes
(2019)The objective of the study was the investigation of the behaviour of cathelicidin-1 in the milk after experimental infection with two prominent bacterial pathogens (experiment 1: Mannheimia haemolytica, experiment 2: M. ... -
Determinants of venous return in steady-state physiology and asphyxia-induced circulatory shock and arrest: an experimental study
(2022)Background: Mean circulatory filling pressure (Pmcf) provides information on stressed volume and is crucial for maintaining venous return. This study investigated the Pmcf and other determinants of venous return in dysrhythmic ... -
Dido mutations trigger perinatal death and generate brain abnormalities and behavioral alterations in surviving adult mice
(2015)Nearly all vertebrate cells have a single cilium protruding from their surface. This threadlike organelle, once considered vestigial, is now seen as a pivotal element for detection of extracellular signals that trigger ... -
Dietary prenylated flavonoid xanthohumol alleviates oxidative damage and accelerates diabetic wound healing via Nrf2 activation
(2022)Diabetic skin ulcer is one of the most common complications in patients suffering diabetes mellitus. Xanthohumol (XN), a hop-derived prenylated dietary flavonoid, has multiple health beneficial bioactivities. In the present ... -
Differential quantitative proteomics study of experimental Mannheimia haemolytica mastitis in sheep
(2019)Objective was the differential quantitative proteomics study of ovine mastitis induced by Mannheimia haemolytica; clinical, microbiological, cytological and histopathological methods were employed for confirmation and ... -
Do trabecular metal and cancellous titanium implants reduce the risk of late haematogenous infection? An experimental study in rabbits
(2021)Aim: This study evaluated the late resistance to haematogenous contamination by microbial pathogens of implants and bone-implant interface and the development of late clinical infection when cementless components with ... -
Dose-Dependent Effects of Ranolazine on Reentrant Ventricular Arrhythmias Induced After Subacute Myocardial Infarction in Rabbits
(2020)Ranolazine has been found to prevent ventricular arrhythmias (VAs) during acute myocardial infarction (AMI). This study aimed to investigate its efficacy on VAs induced several days post-MI. For this purpose, 13 anesthetized ... -
Downregulation of PERK activity and eIF2α serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells article
(2018)Oxidative stress determines cell fate through several mechanisms, among which regulation of mRNA translation by the phosphorylation of the alpha (α) subunit of the translation initiation factor eIF2α at serine 51 (eIF2αP) ... -
Dual IRE1 RNase functions dictate glioblastoma development
(2018)Proteostasis imbalance is emerging as a major hallmark of cancer, driving tumor aggressiveness. Evidence suggests that the endoplasmic reticulum (ER), a major site for protein folding and quality control, plays a critical ... -
Editorial: Cognitive Impairment: Therapy Momentum in the Continuum of Life
(2021)[No abstract available] -
The effect of a hydrocolloid dressing on second intention wound healing in cats
(2018)The objective of the present study was to evaluate the effect of a hydrocolloid dressing on second intention wound healing in cats. Two full-thickness skin wounds, measuring 2 × 2 cm, were created on both sides of the ...