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Browsing by Subject "Stroke"

Now showing items 21-40 of 148

    • Cardiovascular care of patients with stroke and high risk of stroke: The need for interdisciplinary action: A consensus report from the European Society of Cardiology Cardiovascular Round Table 

      Doehner W., Mazighi M., Hofmann B.M., Lautsch D., Hindricks G., Bohula E.A., Byrne R.A., Camm A.J., Casadei B., Caso V., Cognard C., Diener H.-C., Endres M., Goldstein P., Halliday A., Hopewell J.C., Jovanovic D.R., Kobayashi A., Kostrubiec M., Krajina A., Landmesser U., Markus H.S., Ntaios G., Pezzella F.R., Ribo M., Rosano G.M.C., Rubiera M., Sharma M., Touyz R.M., Widimsky P. (2020)
      Comprehensive stroke care is an interdisciplinary challenge. Close collaboration of cardiologists and stroke physicians is critical to ensure optimum utilisation of short- and long-term care and preventive measures in ...

    • Carotid artery plaque echomorphology and its association with histopathologic characteristics 

      Spanos K., Tzorbatzoglou I., Lazari P., Maras D., Giannoukas A.D. (2018)
      Objective: The aim of the study was to determine the association of ultrasonic texture features (severity of stenosis, grey scale median, plaque area, juxtaluminal black area [JBA], and discrete white areas) previously ...

    • Carotid Intima-Media Thickness Progression as Surrogate Marker for Cardiovascular Risk: Meta-Analysis of 119 Clinical Trials Involving 100 667 Patients 

      Willeit P., Tschiderer L., Allara E., Reuber K., Seekircher L., Gao L., Liao X., Lonn E., Gerstein H.C., Yusuf S., Brouwers F.P., Asselbergs F.W., Van Gilst W., Anderssen S.A., Grobbee D.E., Kastelein J.J.P., Visseren F.L.J., Ntaios G., Hatzitolios A.I., Savopoulos C., Nieuwkerk P.T., Stroes E., Walters M., Higgins P., Dawson J., Gresele P., Guglielmini G., Migliacci R., Ezhov M., Safarova M., Balakhonova T., Sato E., Amaha M., Nakamura T., Kapellas K., Jamieson L.M., Skilton M., Blumenthal J.A., Hinderliter A., Sherwood A., Smith P.J., Van Agtmael M.A., Reiss P., Van Vonderen M.G.A., Kiechl S., Klingenschmid G., Sitzer M., Stehouwer C.D.A., Uthoff H., Zou Z.-Y., Cunha A.R., Neves M.F., Witham M.D., Park H.-W., Lee M.-S., Bae J.-H., Bernal E., Wachtell K., Kjeldsen S.E., Olsen M.H., Preiss D., Sattar N., Beishuizen E., Huisman M.V., Espeland M.A., Schmidt C., Agewall S., Ok E., Aşçi G., De Groot E., Grooteman M.P.C., Blankestijn P.J., Bots M.L., Sweeting M.J., Thompson S.G., Lorenz M.W. (2020)
      Background: To quantify the association between effects of interventions on carotid intima-media thickness (cIMT) progression and their effects on cardiovascular disease (CVD) risk. Methods: We systematically collated data ...

    • Carotid plaques and detection of atrial fibrillation in embolic stroke of undetermined source 

      Ntaios G., Perlepe K., Sirimarco G., Strambo D., Eskandari A., Karagkiozi E., Vemmou A., Koroboki E., Manios E., Makaritsis K., Michel P., Vemmos K. (2019)
      OBJECTIVE: To investigate the association between the presence of ipsilateral nonstenotic carotid plaques and the rate of detection of atrial fibrillation (AF) during follow-up in patients with embolic strokes of undetermined ...

    • Causes and Risk Factors of Cerebral Ischemic Events in Patients with Atrial Fibrillation Treated with Non-Vitamin K Antagonist Oral Anticoagulants for Stroke Prevention: The RENo Study 

      Paciaroni M., Agnelli G., Caso V., Silvestrelli G., Seiffge D.J., Engelter S., De Marchis G.M., Polymeris A., Zedde M.L., Yaghi S., Michel P., Eskandari A., Antonenko K., Sohn S.-I., Cappellari M., Tassinari T., Tassi R., Masotti L., Katsanos A.H., Giannopoulos S., Acciarresi M., Alberti A., Venti M., Mosconi M.G., Vedovati M.C., Pierini P., Giustozzi M., Lotti E.M., Ntaios G., Kargiotis O., Monaco S., Lochner P., Bandini F., Liantinioti C., Palaiodimou L., Abdul-Rahim A.H., Lees K., Mancuso M., Pantoni L., Rosa S., Bertora P., Galliazzo S., Ageno W., Toso E., Angelini F., Chiti A., Orlandi G., Denti L., Flomin Y., Marcheselli S., Mumoli N., Rimoldi A., Verrengia E., Schirinzi E., Del Sette M., Papamichalis P., Komnos A., Popovic N., Zarkov M., Rocco A., Diomedi M., Giorli E., Ciccone A., Grory B.C.M., Furie K.L., Bonetti B., Saia V., Guideri F., Acampa M., Martini G., Grifoni E., Padroni M., Karagkiozi E., Perlepe K., Makaritsis K., Mannino M., MacCarrone M., Ulivi L., Giannini N., Ferrari E., Pezzini A., Doronin B., Volodina V., Baldi A., D'Amore C., Deleu D., Corea F., Putaala J., Santalucia P., Nardi K., Risitano A., Toni D., Tsivgoulis G. (2019)
      Background and Purpose-Despite treatment with oral anticoagulants, patients with nonvalvular atrial fibrillation (AF) may experience ischemic cerebrovascular events. The aims of this case-control study in patients with AF ...

    • Characteristics and Outcomes in Patients with COVID-19 and Acute Ischemic Stroke: The Global COVID-19 Stroke Registry 

      Ntaios G., Michel P., Georgiopoulos G., Guo Y., Li W., Xiong J., Calleja P., Ostos F., González-Ortega G., Fuentes B., Alonso De Leciñana M., Díez-Tejedor E., García-Madrona S., Masjuan J., Defelipe A., Turc G., Gonçalves B., Domigo V., Dan G.-A., Vezeteu R., Christensen H., Christensen L.M., Meden P., Hajdarevic L., Rodriguez-Lopez A., Díaz-Otero F., García-Pastor A., Gil-Nuñez A., Maslias E., Strambo D., Werring D.J., Chandratheva A., Benjamin L., Simister R., Perry R., Beyrouti R., Jabbour P., Sweid A., Tjoumakaris S., Cuadrado-Godia E., Campello A.R., Roquer J., Moreira T., Mazya M.V., Bandini F., Matz K., Iversen H.K., González-Duarte A., Tiu C., Ferrari J., Vosko M.R., Salzer H.J.F., Lamprecht B., Dünser M.W., Cereda C.W., Quintero Á.B.C., Korompoki E., Soriano-Navarro E., Soto-Ramírez L.E., Castañeda-Méndez P.F., Bay-Sansores D., Arauz A., Cano-Nigenda V., Kristoffersen E.S., Tiainen M., Strbian D., Putaala J., Lip G.Y.H. (2020)
      Recent case-series of small size implied a pathophysiological association between coronavirus disease 2019 (COVID-19) and severe large-vessel acute ischemic stroke. Given that severe strokes are typically associated with ...

    • Characteristics and outcomes of Embolic Stroke of Undetermined Source according to stroke severity 

      Leventis I., Perlepe K., Sagris D., Sirimarco G., Strambo D., Georgiopoulos G., Eskandari A., Karagkiozi E., Vemmou A., Koroboki E., Manios E., Makaritsis K., Vemmos K., Michel P., Ntaios G. (2020)
      Background and aims: Patients with embolic strokes of undetermined source (ESUS) usually present with mild symptoms. We aimed to compare the baseline characteristics between mild and severe ESUS, identify predictors for ...

    • The characteristics of intracranial plaques of unilateral, anterior circulation embolic stroke of undetermined source: An analysis of different subtypes based on high-resolution imaging 

      Shang Z.-Y., Tao L., Li X.-Q., Yang B.-Q., Ntaios G., Chen H.-S. (2022)
      Background and purpose: The aim was to investigate the characteristics of non-stenotic intracranial plaque (NSIP) in embolic stroke of undetermined source (ESUS) subtypes by high-resolution magnetic resonance imaging. ...

    • Characterization of Patients with Embolic Strokes of Undetermined Source in the NAVIGATE ESUS Randomized Trial 

      Kasner S.E., Lavados P., Sharma M., Wang Y., Wang Y., Dávalos A., Shamalov N., Cunha L., Lindgren A., Mikulik R., Arauz A., Lang W., Czlonkowska A., Eckstein J., Gagliardi R., Amarenco P., Ameriso S.F., Tatlisumak T., Veltkamp R., Hankey G.J., Toni D.S., Bereczki D., Uchiyama S., Ntaios G., Yoon B.-W., Brouns R., DeVries Basson M.M., Endres M., Muir K., Bornstein N., Ozturk S., O'Donnell M., Mundl H., Pater C., Weitz J., Peacock W.F., Swaminathan B., Kirsch B., Berkowitz S.D., Peters G., Pare G., Themeles E., Shoamanesh A., Connolly S.J., Hart R.G., NAVIGATE ESUS Steering Committee and Investigators (2018)
      Background: The New Approach Rivaroxaban Inhibition of Factor Xa in a Global Trial vs. ASA to Prevent Embolism in Embolic Stroke of Undetermined Source (NAVIGATE-ESUS) trial is a randomized phase-III trial comparing ...

    • Clinical risk scores for the prediction of incident atrial fibrillation: a modernized review 

      Louka A.M., Tsagkaris C., Stoica A. (2021)
      Atrial fibrillation (AF) is considered the most common sustained arrhythmia. Major cardiovascular risk factors that have been identified to initiate and perpetuate AF include age, sex, arterial hypertension, heart failure, ...

    • Clopidogrel Monotherapy versus Aspirin Monotherapy in Patients with Established Cardiovascular Disease: Systematic Review and Meta-Analysis 

      Tasoudis P.T., Kyriakoulis I.G., Sagris D., Diener H.C., Ntaios G. (2022)
      Background There is no clear consensus on whether aspirin offers better outcomes in terms of secondary cardiovascular disease prevention compared with clopidogrel. Objective The aim of the study was to compare the safety ...

    • Closure of patent foramen ovale versus medical therapy in patients with cryptogenic stroke or transient ischemic attack: Updated systematic review and meta-analysis 

      Ntaios G., Papavasileiou V., Sagris D., Makaritsis K., Vemmos K., Steiner T., Michel P. (2018)
      Background and Purpose: Previous systematic reviews and meta-analyses compared the efficacy and safety of patent foramen ovale (PFO) closure versus medical treatment in patients with cryptogenic stroke or transient ischemic ...

    • Comparable or higher prevalence of comorbidities in antiphospholipid syndrome vs rheumatoid arthritis: A multicenter, case-control study 

      Panopoulos S., Thomas K., Georgiopoulos G., Boumpas D., Katsiari C., Bertsias G., Drosos A.A., Boki K., Dimitroulas T., Garyfallos A., Papagoras C., Katsimbri P., Tziortziotis A., Adamichou C., Kaltsonoudis E., Argyriou E., Vosvotekas G., Sfikakis P.P., Vassilopoulos D., Tektonidou M.G. (2021)
      Objectives: Evidence on comorbidity prevalence in antiphospholipid syndrome (APS) and its difference from high comorbidity burden rheumatic diseases is limited. Herein, we compare multiple comorbidities between APS and RA. ...

    • Comparison of Risk of Serious Cardiovascular Events after Hemorrhagic versus Ischemic Stroke: A Population-Based Study 

      Akyea R.K., Georgiopoulos G., Iyen B., Kai J., Qureshi N., Ntaios G. (2022)
      Background  Patients with ischemic stroke are considered a very high risk population for subsequent cardiovascular events and guidelines recommend intensive preventive strategies. However, there is no clear recommendation ...

    • Comparison of Risk Scores for the Prediction of the Overall Cardiovascular Risk in Patients with Ischemic Stroke: The Athens Stroke Registry 

      Georgiopoulos G., Ntaios G., Stamatelopoulos K., Manios E., Korompoki E., Vemmou E., Milionis H., Masi S., Lip G.Y.H., Vemmos K. (2019)
      Background: Stratification of overall vascular risk in patients with ischemic stroke is important as it may guide management decisions. Currently available schemes have only modest prognostic accuracy. The TRA2°P score ...

    • Conjugate eye deviation as predictor of acute cortical and subcortical ischemic brain lesions 

      Kaditis D.G., Zintzaras E., Sali D., Kotoulas G., Papadimitriou A., Hadjigeorgiou G.M. (2016)
      Objectives Non-enhanced computed tomography (NECT) of the brain is used to exclude intracranial hemorrhage in patients who are considered for treatment with tissue plasminogen activator due to stroke symptoms. However, ...

    • Continuing versus Stopping Prestroke Antihypertensive Therapy in Acute Intracerebral Hemorrhage: A Subgroup Analysis of the Efficacy of Nitric Oxide in Stroke Trial 

      Krishnan K., Scutt P., Woodhouse L., Adami A., Becker J.L., Cala L.A., Casado A.M., Chen C., Dineen R.A., Gommans J., Koumellis P., Christensen H., Collins R., Czlonkowska A., Lees K.R., Ntaios G., Ozturk S., Phillips S.J., Sprigg N., Szatmari S., Wardlaw J.M., Bath P.M., ENOS Investigators (2016)
      Background and purpose More than 50% of patients with acute intracerebral hemorrhage (ICH) are taking antihypertensive drugs before ictus. Although antihypertensive therapy should be given long term for secondary prevention, ...

    • COVID-19 and ischemic stroke 

      Sagris D., Papanikolaou A., Kvernland A., Korompoki E., Frontera J.A., Troxel A.B., Gavriatopoulou M., Milionis H., Lip G.Y.H., Michel P., Yaghi S., Ntaios G. (2021)
      Since the onset of the COVID-19 pandemic, a substantial proportion of COVID-19 patients had documented thrombotic complications and ischemic stroke. Several mechanisms related to immune-mediated thrombosis, the renin ...

    • Data-driven machine-learning analysis of potential embolic sources in embolic stroke of undetermined source 

      Ntaios G., Weng S.F., Perlepe K., Akyea R., Condon L., Lambrou D., Sirimarco G., Strambo D., Eskandari A., Karagkiozi E., Vemmou A., Korompoki E., Manios E., Makaritsis K., Vemmos K., Michel P. (2021)
      Background and purpose: Hierarchical clustering, a common ‘unsupervised’ machine-learning algorithm, is advantageous for exploring potential underlying aetiology in particularly heterogeneous diseases. We investigated ...

    • Determinants of cognitive performance and decline in 20 diverse ethno-regional groups: A COSMIC collaboration cohort study 

      Lipnicki D.M., Makkar S.R., Crawford J.D., Thalamuthu A., Kochan N.A., Lima-Costa M.F., Castro-Costa E., Ferri C.P., Brayne C., Stephan B., Llibre-Rodriguez J.J., Llibre-Guerra J.J., Valhuerdi-Cepero A.J., Lipton R.B., Katz M.J., Derby C.A., Ritchie K., Ancelin M.-L., Carrière I., Scarmeas N., Yannakoulia M., Hadjigeorgiou G.M., Lam L., Chan W.-C., Fung A., Guaita A., Vaccaro R., Davin A., Kim K.W., Han J.W., Suh S.W., Riedel-Heller S.G., Roehr S., Pabst A., van Boxtel M., Köhler S., Deckers K., Ganguli M., Jacobsen E.P., Hughes T.F., Anstey K.J., Cherbuin N., Haan M.N., Aiello A.E., Dang K., Kumagai S., Chen T., Narazaki K., Ng T.P., Gao Q., Nyunt M.S.Z., Scazufca M., Brodaty H., Numbers K., Trollor J.N., Meguro K., Yamaguchi S., Ishii H., Lobo A., Lopez-Anton R., Santabárbara J., Leung Y., Lo J.W., Popovic G., Sachdev P.S., Cohort Studies of Memory in an International Consortium (COSMIC) (2019)
      Background: With no effective treatments for cognitive decline or dementia, improving the evidence base for modifiable risk factors is a research priority. This study investigated associations between risk factors and ...