• Predictors of Need for Critical Care Support, Adverse Events, and Outcome after Stroke Thrombolysis 

      Papamichalis P., Karagiannis S., Dardiotis E., Chovas A., Papadopoulos D., Zafeiridis T., Babalis D., Paraforos G., Zisopoulou V., Skoura A.-L., Staikos I., Bouliaris K., Papamichalis M., Hadjigeorgiou G., Komnos A. (2018)
      Background: Results from trials and international registries exhibit heterogeneity regarding safety, efficacy, markers of prognosis, and markers of the need for critical care support after intravenous thrombolysis (IVT) ...
    • Rapidly improving acute respiratory distress syndrome in COVID-19: a multi-centre observational study 

      Gavrielatou E., Vaporidi K., Tsolaki V., Tserlikakis N., Zakynthinos G.E., Papoutsi E., Maragkuti A., Mantelou A.G., Karayiannis D., Mastora Z., Georgopoulos D., Zakynthinos E., Routsi C., Zakynthinos S.G., Schenck E.J., Kotanidou A., Siempos I.I. (2022)
      Background: Before the pandemic of coronavirus disease (COVID-19), rapidly improving acute respiratory distress syndrome (ARDS), mostly defined by early extubation, had been recognized as an increasingly prevalent subphenotype ...
    • Relationship between corticosteroid use and incidence of ventilator-associated pneumonia in COVID-19 patients: a retrospective multicenter study 

      Saura O., Rouzé A., Martin-Loeches I., Povoa P., Kreitmann L., Torres A., Metzelard M., Du Cheyron D., Lambiotte F., Tamion F., Labruyere M., Boulle Geronimi C., Luyt C.-E., Nyunga M., Pouly O., Thille A.W., Megarbane B., Saade A., Magira E., Llitjos J.-F., Ioannidou I., Pierre A., Reignier J., Garot D., Baudel J.-L., Voiriot G., Plantefeve G., Morawiec E., Asfar P., Boyer A., Mekontso-Dessap A., Bardaka F., Diaz E., Vinsonneau C., Floch P.-E., Weiss N., Ceccato A., Artigas A., Nora D., Duhamel A., Labreuche J., Nseir S., Bouchereau M., Boyd S., Coelho L., Maizel J., Cuchet P., Zarrougui W., Boyer D., Quenot J.-P., Imouloudene M., Pineton de Chambrun M., Van der Linden T., Arrive F., Voicu S., Azoulay E., Moglia E., Pene F., Cilloniz C., Thevenin D., Larrat C., Argaud L., Guidet B., Contou D., Beurton A., Meguerditchian D., Razazi K., Tsolaki V., Marzouk M., Brunin G., Marois C., Morales L., coVAPid Study Group (2022)
      Background: Ventilator-associated pneumonia (VAP) is common in patients with severe SARS-CoV-2 pneumonia. The aim of this ancillary analysis of the coVAPid multicenter observational retrospective study is to assess the ...
    • Relationship between ventilator-associated pneumonia and mortality in COVID-19 patients: a planned ancillary analysis of the coVAPid cohort 

      Nseir S., Martin-Loeches I., Povoa P., Metzelard M., Du Cheyron D., Lambiotte F., Tamion F., Labruyere M., Makris D., Boulle Geronimi C., Pinetonde Chambrun M., Nyunga M., Pouly O., Mégarbane B., Saade A., Gomà G., Magira E., Llitjos J.-F., Torres A., Ioannidou I., Pierre A., Coelho L., Reignier J., Garot D., Kreitmann L., Baudel J.-L., Voiriot G., Contou D., Beurton A., Asfar P., Boyer A., Thille A.W., Mekontso-Dessap A., Tsolaki V., Vinsonneau C., Floch P.-E., Le Guennec L., Ceccato A., Artigas A., Bouchereau M., Labreuche J., Duhamel A., Rouzé A., Favory R., Préau S., Jourdain M., Poissy J., Leger P.S., Van der Linden T., Veinstein A., Azoulay E., Pene F., Martin M., Razazi K., Plantefeve G., Fartoukh M., Thevenin D., Guidet B., Weiss N., Kouatchet A., Salmon C., Brunin G., Nemlaghi S., Meguerditchian D., Argaud L., Voicu S., Luyt C.-E., Kowalski B., Moglia E., Morales L., Koutsoukou A., Mentzelopoulos S.D., Nora D., Boyd S., Maizel J., Cuchet P., Delforge Q., Quenot J.-P., Boyer D., Cilloniz C., the coVAPid study group (2021)
      Background: Patients with SARS-CoV-2 infection are at higher risk for ventilator-associated pneumonia (VAP). No study has evaluated the relationship between VAP and mortality in this population, or compared this relationship ...
    • The role of antimicrobial resistance on long-term mortality and quality of life in critically ill patients: a prospective longitudinal 2-year study 

      Koukoubani T., Makris D., Daniil Z., Paraforou T., Tsolaki V., Zakynthinos E., Papanikolaou J. (2021)
      Background: In the recent era, antimicrobial resistance has been identified as one of the most important threats to human health worldwide. The rapid emergence of antibiotic-resistant pathogens (ABRP) in the modern intensive ...
    • Secondary bacterial infections are a leading factor triggering New Onset Atrial Fibrillation in intubated ICU Covid-19 ARDS patients 

      Zakynthinos G.E., Tsolaki V., Karavidas N., Vazgiourakis V., Dimeas G., Mantzarlis K., Vavougios G., Makris D. (2022)
      Background: Cardiac arrhythmias, mainly atrial fibrillation (AF), is frequently reported in COVID-19 patients, more often in Intensive Care Unit (ICU) patients, yet causality has not been virtually explored. Moreover, ...
    • Septic shock due to Candida famata (Debaryomyces hansenii) candidemia in an ICU immunocompetent trauma-patient 

      Karapetsa M., Tsolaki V., Arabatzis M., Petinaki E., Velegraki A., Zakynthinos E. (2019)
      Sepsis related to Candida famata (C. famata) fungemia is extremely rare in immunocompetent patients. Moreover, septic shock has not been reported due to this yeast. A previously healthy young multi-trauma male, presented ...
    • Spread of Tst-positive Staphylococcus aureus strains belonging to ST30 clone among patients and healthcareworkers in two intensive care units 

      Papadimitriou-Olivgeris M., Drougka E., Fligou F., Dodou V., Kolonitsiou F., Filos K.S., Anastassiou E.D., Petinaki E., Marangos M., Spiliopoulou I. (2017)
      Staphylococcus aureus is a major cause of infections. Toxic shock syndrome toxin (TSST-1) and Panton-Valentine leukocidin (PVL) are associated with severe clinical syndromes. S. aureus colonizing isolates recovered from ...
    • Survey of methicillin-resistant coagulase-negative staphylococci in the hospitals of central Greece 

      Petinaki, E.; Kontos, F.; Miriagou, V.; Maniati, M.; Hatzi, F.; Maniatis, A. N. (2001)
      A sample of 450 consecutive, non-replicated coagulase-negative staphylococci (CoNS), collected from clinical specimens during the period 2000-2001 from the five major hospitals of Thessaly district (Central Greece) were ...
    • Ten ineffective interventions to prevent ventilator-associated pneumonia 

      Makris D., Luna C., Nseir S. (2018)
      [No abstract available]
    • Toll-like receptor 2, 4 and 9 polymorphisms and their association with ICU-acquired infections in Central Greece 

      Chatzi M., Papanikolaou J., Makris D., Papathanasiou I., Tsezou A., Karvouniaris M., Zakynthinos E. (2018)
      Purpose: To test the potential of four common Toll-like receptor (TLR) polymorphisms to predispose to specific intensive care unit (ICU)-acquired infections and affect outcomes in a Greek ICU. Materials and methods: The ...
    • Validation of the new Sepsis-3 definitions: proposal for improvement in early risk identification 

      Giamarellos-Bourboulis E.J., Tsaganos T., Tsangaris I., Lada M., Routsi C., Sinapidis D., Koupetori M., Bristianou M., Adamis G., Mandragos K., Dalekos G.N., Kritselis I., Giannikopoulos G., Koutelidakis I., Pavlaki M., Antoniadou E., Vlachogiannis G., Koulouras V., Prekates A., Dimopoulos G., Koutsoukou A., Pnevmatikos I., Ioakeimidou A., Kotanidou A., Orfanos S.E., Armaganidis A., Gogos C., the Hellenic Sepsis Study Group (2017)
      Objectives Sepsis-3 definitions generated controversies regarding their general applicability. The Sepsis-3 Task Force outlined the need for validation with emphasis on the quick Sequential Organ Failure Assessment (qSOFA) ...