Μελέτη της διαφοράς διεγερσιμότητας μεταξύ CA1 κυττάρων ραχιαίου και κοιλιακού ιππόκαμπου αρουραίου με τη χρήση προχωρημένων μεθόδων ανάλυσης σήματος
Προβολή/ Άνοιγμα
Συγγραφέας
Βάιος, ΓεώργιοςΌνομα Επιβλέποντος
Ασπροδίνη, Ευτυχία
Ημερομηνία
2002Γλώσσα
el
Σημειώσεις
Παρατηρήσεις έκδοσης: χαμηλής ποιότητας εκτύπωση.
Πρόσβαση
ελεύθερη
Επιτομή
The septal and temporal pole of the rat hippocampus appear to differ
markedly in their anatomical and neurochemical organization.
It is well established both in vivo and in vitro that neurons in temporal
slices of the hippocampus , are more excitable t and more prone to
epileptiform activity than neurons in septal slices.
At the present study intracellular current clamp recordings were made from
pyramidal neurons of the CA1 region of both septal and temporal slices of
the hippocampus.
With the use of parameters in the space of time and frequency and after
statistical analysis the following differences between septal and temporal
slices were established:
They differ on :
1. their waveforms
2. the total power of discharges and thus in the excitability.
3. the λ parameter ( poisson distribution) of the values of interspike
intervals and thus in the excitability. ( the duration of the action
potentials is larger of the temporal slices).
These findings not only come in agreement with previous studies , over the
functional differences between septal and temporal hippocampal slices , but
they seem to verify the hypothesis that the differentation is due to the
intrinsic membrane properties.
Ακαδημαϊκός Εκδότης
Πανεπιστήμιο Θεσσαλίας. Πρόγραμμα Σπουδών Επιλογής. Τμήμα Ιατρικής Βιοχημείας.