• 17-β estradiol attenuates the pro-oxidant activity of corticotropin-releasing hormone in macroendothelial cells 

      Filiponi M., Gougoura S.G., Befani C., Bargiota Α., Liakos P., Koukoulis G.N. (2019)
      Corticotropin-releasing hormone, which is the predominant regulator of neuroendocrine responses to stress, attenuates inflammation through stimulation of glucocorticoid release. Enhanced corticotropin-releasing hormone ...
    • Antithrombotic treatment in patients with stroke and supracardiac atherosclerosis 

      Sagris D., Georgiopoulos G., Leventis I., Pateras K., Pearce L.A., Korompoki E., Makaritsis K., Vemmos K., Milionis H., Ntaios G. (2020)
      Objective To compare the efficacy and safety of oral anticoagulants vs antiplatelets in patients with stroke and atherosclerotic plaques in the aortic arch or cervical or intracranial arteries, collectively described as ...
    • Aortic Arch Atherosclerosis in Patients With Embolic Stroke of Undetermined Source: An Exploratory Analysis of the NAVIGATE ESUS Trial 

      Ntaios G., Pearce L.A., Meseguer E., Endres M., Amarenco P., Ozturk S., Lang W., Bornstein N.M., Molina C.A., Pagola J., Mundl H., Berkowitz S.D., Liu Y.Y., Sen S., Connolly S.J., Hart R.G. (2019)
      Background and Purpose- Aortic arch atherosclerosis (AAA) is a possible source of embolism in patients with embolic stroke of undetermined source. Previous studies reported high rates of embolic events in patients with ...
    • Atrial Fibrillation and Dementia: A Report From the AF-SCREEN International Collaboration 

      Rivard L., Friberg L., Conen D., Healey J.S., Berge T., Boriani G., Brandes A., Calkins H., Camm A.J., Yee Chen L., Lluis Clua Espuny J., Collins R., Connolly S., Dagres N., Elkind M.S.V., Engdahl J., Field T.S., Gersh B.J., Glotzer T.V., Hankey G.J., Harbison J.A., Georg Haeusler K., Hills M.T., Johnson L.S.B., Joung B., Khairy P., Kirchhof P., Krieger D., Lip G.Y.H., Løchen M.-L., Madhavan M., Mairesse G.H., Montaner J., Ntaios G., Quinn T.J., Rienstra M., Rosenqvist M., Sandhu R.K., Smyth B., Schnabel R.B., Stavrakis S., Themistoclakis S., Van Gelder I.C., Wang J.-G., Freedman B. (2022)
      Growing evidence suggests a consistent association between atrial fibrillation (AF) and cognitive impairment and dementia that is independent of clinical stroke. This report from the AF-SCREEN International Collaboration ...
    • Cadherin and Wnt signaling pathways as key regulators in diabetic nephropathy 

      Tziastoudi M., Tsezou A., Stefanidis I. (2021)
      Aim A recent meta-analysis of genome-wide linkage studies (GWLS) has identified multiple genetic regions suggestive of linkage with DN harboring hundreds of genes. Moving this number of genetic loci forward into biological ...
    • Canine hyperlipidaemia 

      Xenoulis P.G., Steiner J.M. (2015)
      Hyperlipidaemia refers to an increased concentration of lipids in the blood. Hyperlipidaemia is common in dogs and has recently emerged as an important clinical condition that requires a systematic diagnostic approach and ...
    • Carotid Bifurcation Geometry and Atherosclerosis 

      Spanos K., Petrocheilou G., Karathanos C., Labropoulos N., Mikhailidis D., Giannoukas A. (2017)
      Hemodynamic changes occurring at the initial segments of the arterial bifurcations appear to play an important role in the development of atherosclerotic plaque. Therefore, arterial geometry might be a potential marker for ...
    • Carotid Intima-Media Thickness and Circulation Markers of Inflammation in Patients With Depression 

      Saleptsis V., Papaliaga M., Spanos K., Kouvelos G., Labropoulos N., Halaris A., Giannoukas A. (2020)
      Objective: Growing evidence indicates that depressive disorders (DDs) are an important risk factor for atherosclerosis. The aim of this study was to evaluate the presence of common carotid artery (CCA) intima-media thickness ...
    • Causes and Risk Factors of Cerebral Ischemic Events in Patients with Atrial Fibrillation Treated with Non-Vitamin K Antagonist Oral Anticoagulants for Stroke Prevention: The RENo Study 

      Paciaroni M., Agnelli G., Caso V., Silvestrelli G., Seiffge D.J., Engelter S., De Marchis G.M., Polymeris A., Zedde M.L., Yaghi S., Michel P., Eskandari A., Antonenko K., Sohn S.-I., Cappellari M., Tassinari T., Tassi R., Masotti L., Katsanos A.H., Giannopoulos S., Acciarresi M., Alberti A., Venti M., Mosconi M.G., Vedovati M.C., Pierini P., Giustozzi M., Lotti E.M., Ntaios G., Kargiotis O., Monaco S., Lochner P., Bandini F., Liantinioti C., Palaiodimou L., Abdul-Rahim A.H., Lees K., Mancuso M., Pantoni L., Rosa S., Bertora P., Galliazzo S., Ageno W., Toso E., Angelini F., Chiti A., Orlandi G., Denti L., Flomin Y., Marcheselli S., Mumoli N., Rimoldi A., Verrengia E., Schirinzi E., Del Sette M., Papamichalis P., Komnos A., Popovic N., Zarkov M., Rocco A., Diomedi M., Giorli E., Ciccone A., Grory B.C.M., Furie K.L., Bonetti B., Saia V., Guideri F., Acampa M., Martini G., Grifoni E., Padroni M., Karagkiozi E., Perlepe K., Makaritsis K., Mannino M., MacCarrone M., Ulivi L., Giannini N., Ferrari E., Pezzini A., Doronin B., Volodina V., Baldi A., D'Amore C., Deleu D., Corea F., Putaala J., Santalucia P., Nardi K., Risitano A., Toni D., Tsivgoulis G. (2019)
      Background and Purpose-Despite treatment with oral anticoagulants, patients with nonvalvular atrial fibrillation (AF) may experience ischemic cerebrovascular events. The aims of this case-control study in patients with AF ...
    • Dietary antioxidant supplements and uric acid in chronic kidney disease: A review 

      Roumeliotis S., Roumeliotis A., Dounousi E., Eleftheriadis T., Liakopoulos V. (2019)
      Increased serum levels of uric acid have been associated with the onset and development of chronic kidney disease (CKD), cardiovascular disease, and mortality, through several molecular pathogenetic mechanisms, such as ...
    • Endothelin-1 plasma levels in hemodialysis treatment - The influence of type 2 diabetes 

      Liakopoulos, V.; Wurth, P.; Mertens, P. R.; Eleftheriadis, T.; Kourti, P.; Voliotis, G.; Heintz, B.; Koukoulis, G. N.; Stefanidis, I. (2005)
      In patients on chronic hemodialysis the prevalence of atherosclerosis is increased and is by far the leading cause of morbidity and mortality. Endothelin-1, an endothelium-derived peptide with vasoconstrictive and mitogenic ...
    • Evidence of deregulated cholesterol efflux in abdominal aortic aneurysm 

      Mourmoura E., Vasilaki A., Giannoukas A., Michalodimitrakis E., Pavlidis P., Tsezou A. (2016)
      Previous studies indicated that lipids may be associated with abdominal aortic aneurysm (AAA); however the molecular mechanism involved is unclear. Our study aimed to investigate the expression pattern of cholesterol efflux ...
    • Exercise and inflammation 

      Metsios G.S., Moe R.H., Kitas G.D. (2020)
      Based on current knowledge deriving from studies in animals and humans (the general population and patients with non-communicable diseases), there is biological plausibility that exercise may have anti-inflammatory effects. ...
    • Favorable and prolonged changes in blood lipid profile after muscle-damaging exercise 

      Nikolaidis, M. G.; Paschalis, V.; Giakas, G.; Fatouros, I. G.; Sakellariou, G. K.; Theodorou, A. A.; Koutedakis, Y.; Jamurtas, A. Z. (2008)
      Purpose: To examine the effect of repeated muscle-damaging exercise on the time-course changes in blood lipid and lipoprotein profile and compare them with changes in indices of muscle function and damage. Methods: Twelve ...
    • Full blood count and peripheral arterial disease severity and prognosis 

      Spanos K., Matsagkas M., Giannoukas A. (2017)
      [No abstract available]
    • Histology and immunohistochemistry of radial arteries are suggestive of an interaction between calcification and early atherosclerotic lesions in chronic kidney disease 

      Lysitska A., Galanis N., Skandalos I., Nikolaidou C., Briza S., Fylaktou A., Lioulios G., Mitsoglou Z., Papadopoulou D., Antoniadis N., Papagianni A., Stangou M. (2021)
      Background and Objectives: recent studies suggest an implication of immune mechanisms in atherosclerotic disease. In this paper, the interaction between inflammation, calcification, and atherosclerosis on the vessel walls ...
    • Imaging predictive factors of abdominal aortic aneurysm growth 

      Nana P., Spanos K., Dakis K., Brodis A., Kouvelos G. (2021)
      Background: Variable imaging methods may add important information about abdominal aortic aneurysm (AAA) progression. The aim of this study is to assess available literature data regarding the predictive imaging factors ...
    • Immunity, Vascular Aging and Stroke 

      Louka A.-M., Sagris D., Ntaios G. (2022)
      Stroke is one of the most devastating manifestations of cardiovascular disease. Growing age, arterial hypertension, and atherosclerosis are identified as independent risk factors for stroke, primarily due to structural and ...
    • Intracranial and systemic atherosclerosis in the NAVIGATE ESUS trial: Recurrent stroke risk and response to antithrombotic therapy 

      Ameriso S.F., Amarenco P., Pearce L.A., Perera K.S., Ntaios G., Lang W., Bereczki D., Uchiyama S., Kasner S.E., Yoon B.-W., Lavados P., Firstenfeld A., Mikulik R., Povedano G.P., Ferrari J., Mundl H., Berkowitz S.D., Connolly S.J., Hart R.G. (2020)
      Background: Non-stenotic intracranial and systemic atherosclerosis are associated with ischemic stroke. We report frequency and response to anticoagulant vs. antiplatelet prophylaxis of patients with embolic stroke of ...