• Benefits and Limitations of TKIs in Patients with Medullary Thyroid Cancer: A Systematic Review and Meta-Analysis 

      Efstathiadou Z.A., Tsentidis C., Bargiota A., Daraki V., Kotsa K., Ntali G., Papanastasiou L., Tigas S., Toulis K., Pazaitou-Panayiotou K., Alevizaki M. (2021)
      Introduction: Tyrosine kinase inhibitors (TKIs) have been used in patients with advanced medullary thyroid carcinoma (MTC); however, data on their effectiveness and safety are limited. The aim of this systematic review and ...
    • Bilateral Pleural Effusion in Rheumatoid Arthritis: Think Beyond the Obvious 

      Dimeas I.E., Sinis S.I., Dimeas G.E., Daniil Z. (2022)
      An 86-year-old woman, non-smoker, with a medical history of rheumatoid arthritis for 20 years (stable at 5mg of prednisolone) was referred from a peripheral hospital to the Department of Respiratory Medicine of our tertiary ...
    • Cryoglobulinemia due to chronic viral hepatitis infections is not a major problem in clinical practice 

      Christodoulou, D. K.; Dalekos, G. N.; Merkouropoulos, M. H.; Kistis, K. G.; Georgitsi, G.; Zervou, E.; Zachou, K.; Tsianos, E. V. (2001)
      Background: Essential mixed cryoglobulinemia (EMC) is a systemic disease frequently associated with chronic viral hepatitis. This study was conducted in order to assess the prevalence of EMC in patients with hepatitis B ...
    • Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations 

      Boer C.G., Hatzikotoulas K., Southam L., Stefánsdóttir L., Zhang Y., Coutinho de Almeida R., Wu T.T., Zheng J., Hartley A., Teder-Laving M., Skogholt A.H., Terao C., Zengini E., Alexiadis G., Barysenka A., Bjornsdottir G., Gabrielsen M.E., Gilly A., Ingvarsson T., Johnsen M.B., Jonsson H., Kloppenburg M., Luetge A., Lund S.H., Mägi R., Mangino M., Nelissen R.R.G.H.H., Shivakumar M., Steinberg J., Takuwa H., Thomas L.F., Tuerlings M., Loughlin J., Arden N., Birrell F., Carr A., Deloukas P., Doherty M., McCaskie A.W., Ollier W.E.R., Rai A., Ralston S.H., Spector T.D., Wallis G.A., Martinsen A.E., Willer C., Fors E.A., Mundal I., Hagen K., Nilsen K.B., Lie M.U., Børte S., Brumpton B., Nielsen J.B., Fritsche L.G., Zhou W., Heuch I., Storheim K., Tyrpenou E., Koukakis A., Chytas D., Evangelopoulos D.S., Efstathios C., Pneumaticos S., Nikolaou V.S., Malizos K., Anastasopoulou L., Abecasis G., Baras A., Cantor M., Coppola G., Deubler A., Economides A., Lotta L.A., Overton J.D., Reid J.G., Shuldiner A., Karalis K., Siminovitch K., Beechert C., Forsythe C., Fuller E.D., Gu Z., Lattari M., Lopez A., Schleicher T.D., Padilla M.S., Widom L., Wolf S.E., Pradhan M., Manoochehri K., Bai X., Balasubramanian S., Boutkov B., Eom G., Habegger L., Hawes A., Krasheninina O., Lanche R., Mansfield A.J., Maxwell E.K., Nafde M., O'Keeffe S., Orelus M., Panea R., Polanco T., Rasool A., Salerno W., Staples J.C., Li D., Sharma D., Banerjee I., Bovijn J., Locke A., Verweij N., Haas M., Hindy G., De T., Akbari P., Sosina O., Ferreira M.A.R., Jones M.B., Mighty J., LeBlanc M.G., Mitnaul L.J., Babis G.C., Cheung J.P.Y., Kang J.H., Kraft P., Lietman S.A., Samartzis D., Slagboom P.E., Stefansson K., Thorsteinsdottir U., Tobias J.H., Uitterlinden A.G., Winsvold B., Zwart J.-A., Davey Smith G., Sham P.C., Thorleifsson G., Gaunt T.R., Morris A.P., Valdes A.M., Tsezou A., Cheah K.S.E., Ikegawa S., Hveem K., Esko T., Wilkinson J.M., Meulenbelt I., Lee M.T.M., van Meurs J.B.J., Styrkársdóttir U., Zeggini E., arcOGEN Consortium, HUNT All-In Pain, ARGO Consortium, Regeneron Genetics Center (2021)
      Osteoarthritis affects over 300 million people worldwide. Here, we conduct a genome-wide association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and identify 100 independently associated ...
    • Early primary biliary cirrhosis: A new association with erythema nodosum of unknown origin 

      Dalekos, G. N.; Gatselis, N. K.; Zachou, K. (2010)
      Primary biliary cirrhosis (PBC) is associated with immune-mediated dermatologic disorders. The association of PBC with erythema nodosum (EN) seems rare. We report two females (42 and 44 years old) with low-grade fever, ...
    • The effect of injection volume on long-term outcomes of US-guided subacromial bursa injections 

      Klontzas M.E., Vassalou E.E., Zibis A.H., Karantanas A.H. (2020)
      Purpose: Limited data exist on the efficacy of high- compared to low-volume US-guided corticosteroid injections (CI) in the subacromial-subdeltoid (SA-SD) bursa. Our purpose was to compare the short- and long-term efficacy ...
    • Evaluation of the Perceptions, Attitudes and Practices among Greek Non-Professional Athletes Visiting a Public Hospital during March 2022, towards COVID-19 Vaccination and Its Consequences on Sports Training and Sports Activity 

      Marinos G., Lamprinos D., Georgakopoulos P., Kavoukidis N., Oikonomou E., Zoumpoulis G., Siasos G., Schizas D., Nikolopoulos A., Botonis P.G., Damaskos C., Rachiotis G., Lagiou P., Orfanos P. (2022)
      Sports have been majorly impacted by the COVID-19 pandemic. After the lockdown period, vaccination and protocols were implemented to return to normality. We aimed to assess the attitudes and practices related to COVID-19 ...
    • Imported Chikungunya fever case in Greece in June 2014 and public health response 

      Tsiodras S., Pervanidou D., Papadopoulou E., Kavatha D., Baka A., Koliopoulos G., Badieritakis E., Michaelakis A., Gavana E., Patsoula E., Tsimpos I., Gioksari T., Kyriazopoulou E., Vakali A., Pavli A., Maltezou H.C., Georgakopoulou T., Hadjichristodoulou C., Kremastinou J., Papa A. (2016)
      We report about the first imported case of Chikungunya fever in Greece in a Greek traveler returning from the Dominican Republic and the associated public health response. We investigated the case and performed focused ...
    • Infliximab therapy for patients with active and refractory spondyloarthropathies at the dose of 3 mg/kg: A 20-month open treatment 

      Cherouvim, E. P.; Zintzaras, E.; Boki, K. A.; Moutsopoulos, H. M.; Manoussakis, M. N. (2004)
      Background: Infliximab at the dose of 5 mg/kg per infusion has been shown effective for the treatment of active spondyloarthropathies. It is not clear if the 5 mg/kg is required in most patients. Objective: To evaluate the ...
    • Interstitial lung disease in anti-synthetase syndrome 

      Kourkouni E., Mitsogiannis G., Simopoulou T., Liaskos C., Katsiari C.G., Daniil Z., Gourgoulianis K., Bogdanos D.P., Sakkas L.I. (2019)
      Anti-synthetase syndrome is an autoimmune disorder characterized by the presence of autoantibodies against aminoacyl transfer RNA (tRNA) synthetases, and myositis, interstitial lung disease (ILD), arthritis, fever and ...
    • Lamivudine plus interleukin-12 combination therapy in chronic hepatitis B: Antiviral and immunological activity 

      Rigopoulou, E. I.; Suri, D.; Chokshi, S.; Mullerova, I.; Rice, S.; Tedder, R. S.; Williams, R.; Naoumov, N. V. (2005)
      Interleukin-12 (IL-12) is an immunomodulatory cytokine that promotes cellular immunity. Pre-clinical data suggest that IL-12 inhibits hepatitis B virus (HBV) replication by stimulating interferon-gamma (IFN-γ) production. ...
    • MRI of the hip: Current concepts on bone marrow oedema 

      Klontzas M.E., Zibis A.H., Vassalou E.E., Karantanas A.H. (2017)
      Bone marrow oedema (BME) is commonly found in hip MR imaging. BME is a nonspecific finding which can be related to a wide variety of diseases. However, there are cases where its existence or its pattern can narrow the ...
    • Patient-reported quality of life after primary major joint arthroplasty: A prospective comparison of hip and knee arthroplasty 

      Dailiana Z.H., Papakostidou I., Varitimidis S., Liaropoulos L., Zintzaras E., Karachalios T., Michelinakis E., Malizos K.N. (2015)
      Background: To investigate and compare the impact of primary hip (THA) and knee (TKA) arthroplasty on quality of life in patients with osteoarthritis, to determine patients' satisfaction with total joint arthroplasty, and ...
    • Patients with haemoglobinopathies and chronic hepatitis C: A real difficult to treat population in 2016? 

      Zachou K., Arvaniti P., Gatselis N.K., Azariadis K., Papadamou G., Rigopoulou E., Dalekos G.N. (2017)
      Background & objectives: In the past, patients with haemoglobinopathies were at high risk of acquiring hepatitis C virus (HCV) due to multiple transfusions before HCV screening. In these patients, the coexistence of ...
    • Pneumomediastinum in MDA5-associated clinically amyopathic dermatomyositis 

      Kotsiou O.S., Daniil Z., Gourgoulianis K.I. (2017)
      [No abstract available]
    • Postacute sequelae of SARS-CoV-2 infection. Osteonecrosis must not be overlooked 

      Koutalos A.A., Stefanou N., Malizos K.N. (2022)
      Recovery from COVID-19 is not always uneventful, especially in critically ill hospitalized patients. Persistent symptoms including fatigue/ weakness, shortness of breath, anxiety, and depression have been described at ...
    • Pulmonary infection by Rhodococcus equi presenting with positive Ziehl-Neelsen stain in a patient with human immunodeficiency virus: A case report 

      Spiliopoulou, A.; Assimakopoulos, S. F.; Foka, A.; Kolonitsiou, F.; Lagadinou, M.; Petinaki, E.; Anastassiou, E. D.; Spiliopoulou, I.; Marangos, M. (2014)
      Introduction: Patients with human immunodeficiency virus carry a significant risk of contracting opportunistic infections. The worldwide increased incidence of tuberculosis has instituted pulmonary tuberculosis as an ...
    • Quadratus femoris tear as an unusual cause of hip pain: A case report 

      Zibis A.H., Fyllos A.H., Karantanas A.H., Raoulis V., Karachalios T.S., Arvanitis D.L. (2016)
      Purpose: To show that quadratus femoris muscle partial or complete tear is an extremely rare if not underdiagnosed cause of hip pain. Methods: We present the case of a 75-year-old Caucasian woman with spontaneous non-traumatic ...
    • A Randomized, Placebo-Controlled Study of Romosozumab for the Treatment of Hip Fractures 

      Schemitsch E.H., Miclau T., Karachalios T., Nowak L.L., Sancheti P., Poolman R.W., Caminis J., Daizadeh N., Dent-Acosta R.E., Egbuna O., Chines A., Maddox J., Grauer A., Bhandari M. (2020)
      Background:Romosozumab is a bone-forming antibody that increases bone formation and decreases bone resorption. We conducted a double-blinded, randomized, phase-2, dose-finding trial to evaluate the effect of romosozumab ...
    • Real world experience of brodalumab treatment in patients with moderate-to-severe plaque psoriasis in the Greek population: Results from an interim analysis of the BrIDGE study 

      Rigopoulos D., Angelakopoulos C., Apalla Z., Georgiou S., Delli F., Drosos A., Zafiriou E., Katsantonis J., Lazaridou E., Panagakis P., Papadavid E., Papakonstantis M., Roussaki-Schulze A.-V., Sotiriou E., Anastasiadis G., Tampouratzi E., Chasapi V., Sfaelos K., Ioannides D., The BrIDGE Study Group (2022)
      Brodalumab's clinical efficacy and favorable safety profile have been demonstrated during controlled clinical trials, but real-world data remain scarce. BrIDGE, an ongoing 104 week, observational, prospective, multicenter ...