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Πλοήγηση ανά Θέμα "alpha-synuclein"

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    • Autoantibodies to alpha-synuclein in inherited Parkinson's disease 

      Papachroni, K. K.; Ninkina, N.; Papapanagiotou, A.; Hadjigeorgiou, G. M.; Xiromerisiou, G.; Papadimitriou, A.; Kalofoutis, A.; Buchman, V. L. (2007)
      Neurodegeneration in Parkinson's disease (PD) is accompanied by a local immune reaction in the affected brain regions. It is well established that alpha-synuclein is directly implicated in the pathogenesis of PD. Development ...

    • Clinical, neuropathological and genotypic variability in SNCA A53T familial Parkinson's disease 

      Markopoulou, K.; Dickson, D. W.; McComb, R. D.; Wszolek, Z. K.; Katechalidou, L.; Avery, L.; Stansbury, M. S.; Chase, B. A. (2008)
      Individuals with familial Parkinson's disease (PD) due to a monogenic defect can show considerable clinical and neuropathological variability. To identify factors underlying this variability, histopathological analysis was ...