Sfoglia per Soggetto "Rat"
Items 1-16 di 16
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Crocins, the active constituents of Crocus Sativus L., counteracted ketamine-induced behavioural deficits in rats
(2014)Experimental evidence indicates that the non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist ketamine impairs cognition and can mimic certain aspects of positive and negative symptoms of schizophrenia in rodents. ... -
Crocus sativus L. extracts antagonize memory impairments in different behavioural tasks in the rat
(2006)The effects of extracts of Crocus sativus L. (CSE), on memory were investigated in the rat by using the object recognition and the step-through passive avoidance task. In the first study, post-training administration of ... -
Effect of anoxia and hypoglycaemia on the expression of neuronal cell markers in the rat retina and hippocampus: Development of a rat ex vivo ischemia model
(2007)Neuronal ischemia leads to neuronal cells death due to glucose and oxygen deprivation. The goal of this study was the development of a rat ex vivo ischemia model for the deferential identification of anoxic and hypoglycaemic ... -
Effects of the active constituent of Crocus sativus L. crocin on recognition and spatial rats' memory
(2007)Crocus Sativus L. is a plant cultivated in various parts of the world. Its involvement in learning and memory processes has been proposed. The present study was designed to investigate in the rat the effects of the active ... -
Effects of the active constituents of Crocus sativus L., crocins, in an animal model of anxiety
(2008)Crocus sativus L. is a plant cultivated in various parts of the world. Crocins are among the active components of Crocus sativus L. The present study was designed to investigate in the rat whether or not crocins possess ... -
Effects of the active constituents of Crocus Sativus L., crocins, in an animal model of obsessive-compulsive disorder
(2012)Crocins are among the active components of the plant Crocus Sativus L C. Sativus L and its constituents were effective in different models of psychiatric disorders including anxiety and depression. Obsessive-compulsive ... -
Effects of the nitric oxide synthase inhibitor L-NAME on different memory components as assessed in the object recognition task in the rat
(2010)Nitric oxide (NO) is sought to be an intracellular messenger in the central nervous system and its implication in learning and memory is well documented. Compounds that inhibit nitric oxide synthase (NOS), the key synthesizing ... -
The metabotropic glutamate 2/3 receptor agonist LY379268 counteracted ketamine-and apomorphine-induced performance deficits in the object recognition task, but not object location task, in rats
(2014)Experimental evidence indicates that the non competitive N-methyl-D-aspartate (NMDA) receptor antagonist ketamine and the mixed dopamine (DA) D-1/D-2 receptor agonist apomorphine induce schizophrenia-like symptoms in ... -
The metabotropic glutamate 2/3 receptor agonist LY379268 induces anxiety-like behavior at the highest dose tested in two rat models of anxiety
(2013)The activation of Group If metabotropic glutamate 2/3 (mGlu(2/3)) receptors reduces the excessive glutamate release that is hypothesized to be associated with neurodegenerative and psychiatric disorders. LY379268 is a ... -
The metabotropic glutamate 2/3 receptor antagonist LY341495 differentially affects recognition memory in rats
(2012)Experimental evidence suggests that metabotropic glutamate 2/3 (mGlu2/3) receptor antagonists affect cognitive function, although contradictory findings have been reported. To clarify the role of mGlu2/3 receptor antagonists ... -
The nitric oxide (NO) donor molsidomine antagonizes scopolamine and L-NAME-induced performance deficits in a spatial memory task in the rat
(2009)Nitric oxide (NO) is considered as an intracellular messenger in the brain. Its involvement in learning and memory processes has been proposed. Compounds that inhibit NO synthase (NOS), the key synthesizing enzyme, may ... -
Nitric oxide modulates apomorphine-induced recognition memory deficits in rats
(2012)Nitric oxide (NO) is an important intracellular messenger in the brain. The implication of NO in schizophrenia is well documented although it is not yet clear whether net over or underproduction of NO is typical of this ... -
The nitric oxide-releasing derivative of ferulic acid NCX 2057 antagonized delay-dependent and scopolamine-induced performance deficits in a recognition memory task in the rat
(2010)Nitric oxide (NO) is considered as an intracellular messenger in the brain. its involvement in learning and memory processes has been proposed. The present study was designed to investigate the effects of the NO-releasing ... -
Pre-training administration of anesthetic ketamine differentially affects rats' spatial and non-spatial recognition memory
(2009)There is poor experimental evidence concerning the effects of anesthetic doses of the non-competitive NMDA receptor antagonist ketamine on rodents' memory abilities. The present study was designed to investigate a) the ... -
Repeated administration of the nitric oxide synthase inhibitor L-NAME differentially affects rats' recognition memory
(2011)Nitric oxide (NO) is sought to be an intracellular messenger in the central nervous system and its implication in learning and memory is well documented. Compounds that inhibit nitric oxide synthase (NOS), the key synthesizing ... -
WIN55,212-2 impairs non-associative recognition and spatial memory in rats via CB1 receptor stimulation
(2014)Endogenous and exogenous cannabinoids modulate learning and memory primarily via the cannabinoid type 1 receptor (CB1R). A variety of experimental procedures has focused on the role of CB1R in various aspects of learning ...