Auflistung Nach Schlagwort "CYP1A2"
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Development and validation of a reversed-phase HPLC method for CYP1A2 phenotyping by use of a caffeine metabolite ratio in saliva
(2015)CYP1A2 is important for metabolizing various clinically used drugs. Phenotyping of CYP1A2 may prove helpful for drug individualization therapy. Several HPLC methods have been developed for quantification of caffeine ... -
In vivo evaluation of CUP1A2 and CYP2A6 activities in a Greek population during menopause
(2008)Human CYP enzyme system is involved in the metabolism of various endogenous compounds. Previous studies have shown that CYP activity is influenced by age and gender. In the present study caffeine metabolites were used for ... -
In vivo evaluation of CYP1A2 CYP2A6, NAT-2 and xanthine oxidase activities in a Greek population sample by the RP-HPLC monitoring of caffeine metabolic ratios
(2007)A RP-HPLC method was developed for the assessment of caffeine and its metabolites in urine and was used for the evaluation of the CYP1A2, CYP2A6, xanthine oxidase (XO) and N-acetyl-transferase-2 (NAT-2) in vivo activities ... -
Ανάλυση των μεταβολιτών της καφεΐνης στα ούρα για τον προσδιορισμό της δραστηριότητας του CYP1A2 με τη μέθοδο της υγρής χρωματογραφίας υψηλής πίεσης
(2002)Caffeine metabolism via the N-3 demethylation pathway is sequentially catalyzed by cytochrome P4501A2 (CYP1A2), xanthine oxidase and N-acetyl-transferase. The activity of CYP1A2 can be estimated from the urinary metabolic ...