Listar por tema "complementary DNA"

Decreased Expression of the CD3ζ Chain in T Cells Infiltrating the Synovial Membrane of Patients with Osteoarthritis

Sakkas, L. I.; Koussidis, G.; Avgerinos, E.; Gaughan, J.; Platsoucas, C. D. (2004)

Osteoarthritis (OA) is a heterogeneous disease which rheumatologists consider to be noninflammatory. However, recent studies suggest that, at least in certain patients, OA is an inflammatory disease and that patients often ...

Development of a multiplex RT-PCR assay for the identification of recombination types at different genomic regions of vaccine-derived polioviruses

Dimitriou T.G., Kyriakopoulou Z., Tsakogiannis D., Fikatas A., Gartzonika C., Levidiotou-Stefanou S., Markoulatos P. (2016)

Polioviruses (PVs) are the causal agents of acute paralytic poliomyelitis. Since the 1960s, poliomyelitis has been effectively controlled by the use of two vaccines containing all three serotypes of PVs, the inactivated ...

Endocrine resistance and epigenetic reprogramming in estrogen receptor positive breast cancer

Dimitrakopoulos F.-I., Kottorou A., Tzezou A. (2021)

Despite the enormous advances during the last three decades, breast cancer continues to be the most frequent type of cancer as well as one of the most frequent cancer-related causes of death in women. Therapeutic management ...

Expression of human serum albumin (HSA) mRNA in human granulosa cells: Potential correlation of the 95 amino acid long carboxyl terminal of HSA to gonadotrophin surge-attenuating factor

Karligiotou, E.; Kollia, P.; Kallitsaris, A.; Messinis, I. E. (2006)

Introduction: According to previous studies, gonadotrophin surge-attenuating factor (GnSAF), which is assumed to be produced in human granulosa cells, has a homology with the carboxyl terminal of the human serum albumin ...

First-Time Detection of Porcine Reproductive and Respiratory Syndrome Virus and Porcine Circovirus 2 in an Albanian Farrow-to-Finish Herd

Papatsiros V.G., Chaintoutis S.C., Psalla D., Maragkakis G.G., Christodoulopoulos G., Dovas C.I. (2018)

The purpose of this case report is to describe for the first time concurrent porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus 2 (PCV-2) infections in a commercial farrow-to-finish pig farm ...

FV vectors as alternative gene vehicles for gene transfer in HSCs

Simantirakis E., Tsironis I., Vassilopoulos G. (2020)

Hematopoietic Stem Cells (HSCs) are a unique population of cells, capable of reconstituting the blood system of an organism through orchestrated self-renewal and differentiation. They play a pivotal role in stem cell ...

Immunoglobulin genes in multiple myeloma: Expressed and non-expressed repertoires, heavy and light chain pairings and somatic mutation patterns in a series of 101 cases

Hadzidimitriou, A.; Stamatopoulos, K.; Belessi, C.; Lalayianni, C.; Stavroyianni, N.; Smilevska, T.; Hatzi, K.; Laoutaris, N.; Anagnostopoulos, A.; Kollia, P.; Fassas, A. (2006)

Background and Objectives. The available data on the immunoglobulin gene (IG) repertoire in multiple myeloma (MM) derive mainly from heavy chains; considerably less is known about light chains. We assessed in parallel IGH ...

Neural Differentiation of Human Dental Mesenchymal Stem Cells Induced by ATRA and UDP-4: A Comparative Study

Koutsoumparis A.E., Patsiarika A., Tsingotjidou A., Pappas I., Tsiftsoglou A.S. (2022)

Human mesenchymal stem cells (MSC) are multipotent stem cells, which are isolated from various sources. Currently, there is a worldwide interest for dental MSC to be used against neurodegenerative diseases, since they ...

A novel deep intronic SERPING1 variant as a cause of hereditary angioedema due to C1-inhibitor deficiency

Vatsiou S., Zamanakou M., Loules G., Psarros F., Parsopoulou F., Csuka D., Valerieva A., Staevska M., Porebski G., Obtulowicz K., Magerl M., Maurer M., Speletas M., Farkas H., Germenis A.E. (2020)

Background: In about 5% of patients with hereditary angioedema due to C1-inhibitor deficiency (C1-INH-HAE) no mutation in the SERPING1 gene is detected. Methods: C1-INH-HAE cases with no mutation in the coding region of ...

Olive oil with high polyphenolic content induces both beneficial and harmful alterations on rat redox status depending on the tissue

Kouka P., Tekos F., Papoutsaki Z., Stathopoulos P., Halabalaki M., Tsantarliotou M., Zervos I., Nepka C., Liesivuori J., Rakitskii V.N., Tsatsakis A., Veskoukis A.S., Kouretas D. (2020)

Olive oil (OO) possesses a predominant role in the diet of Mediterranean countries. According to a health claim approved by the European Food Safety Authority, OO protects against oxidative stress‑induced lipid peroxidation ...

Reporting on the Role of miRNAs and Affected Pathways on the Molecular Backbone of Ovarian Insufficiency: A Systematic Review and Critical Analysis Mapping of Future Research

Rapani A., Nikiforaki D., Karagkouni D., Sfakianoudis K., Tsioulou P., Grigoriadis S., Maziotis E., Pantou A., Voutsina A., Pantou A., Koutsilieris M., Hatzigeorgiou A., Pantos K., Simopoulou M. (2021)

Ovarian insufficiency is identified as a perplexing entity in the long list of pathologies impairing fertility dynamics. The three distinct classifications of ovarian insufficiency are poor ovarian response, premature ...

The role of the NLRP3 inflammasome and the activation of IL-1β in the pathogenesis of chronic viral hepatic inflammation

Molyvdas A., Georgopoulou U., Lazaridis N., Hytiroglou P., Dimitriadis A., Foka P., Vassiliadis T., Loli G., Phillipidis A., Zebekakis P., Germenis A.E., Speletas M., Germanidis G. (2018)

Background and aims: Chronic viral hepatitis is a prevalent disease with major health implications. Its underlying pathophysiological mechanisms are not fully understood. IL-1β and the NLRP3 inflammasome involvement has ...

WarmStart colorimetric LAMP for the specific and rapid detection of HPV16 and HPV18 DNA

Daskou M., Tsakogiannis D., Dimitriou T.G., Amoutzias G.D., Mossialos D., Kottaridi C., Gartzonika C., Markoulatos P. (2019)

Background and objectives: Persistent infection with High-Risk HPV genotypes is the principal cause for the development of cervical cancer with HPV16 and HPV18 to be the most frequently identified HPV genotypes observed ...

WarmStart colorimetric RT-LAMP for the rapid, sensitive and specific detection of Enteroviruses A–D targeting the 5′UTR region

Daskou M., Dimitriou T.G., Alexopoulou D.S., Tsakogiannis D., Amoutzias G.D., Mossialos D., Kyriakopoulou Z., Markoulatos P. (2021)

Aims: The aim of the present study was to develop a colorimetric LAMP assay for the detection of enteroviruses belonging to species A–D targeting the 5′ untranslated region (5′ UTR) of enteroviruses genome. Methods and ...