Listar por tema "cell function"

17-β estradiol attenuates the pro-oxidant activity of corticotropin-releasing hormone in macroendothelial cells

Filiponi M., Gougoura S.G., Befani C., Bargiota Α., Liakos P., Koukoulis G.N. (2019)

Corticotropin-releasing hormone, which is the predominant regulator of neuroendocrine responses to stress, attenuates inflammation through stimulation of glucocorticoid release. Enhanced corticotropin-releasing hormone ...

The impact of diet upon mitochondrial physiology (Review)

KYRIAZIS I.D., Vassi E., Alvanou M., Angelakis C., Skaperda Z., TEKOS F., Garikipati V.N.S., SPANDIDOS D.A., Kouretas D. (2022)

Mitochondria are considered the 'powerhouses' of cells, generating the essential energy in the form of adenosine triphosphate that they need for their energy demands. Nevertheless, their function is easily adaptable as ...

Inhibition of the Na-H + exchanger isoform-1 and the extracellular signal-regulated kinase induces apoptosis: A time course of events

Konstantinidis, D.; Koliakos, G.; Vafia, K.; Liakos, P.; Bantekas, C.; Trachana, V.; Kaloyianni, M. (2006)

Aims: The present study attempts to shed light on the role and the relative position of the Na +/H + exchanger isoform 1 (NHE1) and the extracellular signal-regulated kinase (ERK) in HEp-2 cell signaling pathways concerning ...

Molecular proteomic characterization of a pediatric medulloblastoma xenograft

Tsangaris G.T., Dimas K., Malamou A., Katsafadou A., Papathanasiou C., Stravopodis D.J., Vorgias C.E., Gazouli M., Anagnostopoulos A.K. (2017)

Background/Aim: Medulloblastoma (MBL), an archetypal primitive neuroectodermal tumor of the cerebellum, is the most common pediatric central nervous system malignancy representing approximately 20% of all childhood brain ...

Myeloid-derived suppressor cells in prostate cancer: Present knowledge and future perspectives

Koinis F., Xagara A., Chantzara E., Leontopoulou V., Aidarinis C., Kotsakis A. (2022)

Several lines of research are being investigated to better understand mechanisms implicated in response or resistance to immune checkpoint blockade in prostate cancer (PCa). Myeloid-derived suppressor cells (MDSCs) have ...

Novel HIF-2α interaction with Reptin52 impairs HIF-2 transcriptional activity and EPO secretion

Gkotinakou I.M., Befani C., Samiotaki M., Panayotou G., Liakos P. (2021)

Hypoxia-inducible factor 2 (HIF-2), is essential for cellular response to hypoxia and holds an important role in erythropoiesis, angiogenesis, tissue invasion and metastasis, thus, constituting an important therapeutic ...

Reporting on the Role of miRNAs and Affected Pathways on the Molecular Backbone of Ovarian Insufficiency: A Systematic Review and Critical Analysis Mapping of Future Research

Rapani A., Nikiforaki D., Karagkouni D., Sfakianoudis K., Tsioulou P., Grigoriadis S., Maziotis E., Pantou A., Voutsina A., Pantou A., Koutsilieris M., Hatzigeorgiou A., Pantos K., Simopoulou M. (2021)

Ovarian insufficiency is identified as a perplexing entity in the long list of pathologies impairing fertility dynamics. The three distinct classifications of ovarian insufficiency are poor ovarian response, premature ...

Silver nanoparticles alter cell adhesion and proliferation of sheep primary mesothelial cells

Arsenopoulou Z.V., Taitzoglou I.A., Molyvdas P.-A., Gourgoulianis K.I., Hatzoglou C., Zarogiannis S.G. (2018)

Background: Human exposure to engineered nanoparticles has been linked to pleural effusion, inflammation and fibrosis. Silver nanoparticles (AgNPs) are widely used in medical and domestic products, increasing the risk of ...