Listar por tema "Multivariate Analysis"

Adherence to Mediterranean Diet and Frailty

Ntanasi E., Yannakoulia M., Kosmidis M.-H., Anastasiou C.A., Dardiotis E., Hadjigeorgiou G., Sakka P., Scarmeas N. (2018)

Objective: Το investigate associations between adherence to the Mediterranean diet and frailty in a Greek population of older adults. Design: Cross-sectional study. Setting: Data were drawn from the Hellenic longitudinal ...

Age- A nd sex-specific analysis of patients with embolic stroke of undetermined source

Ntaios G., Lip G.Y.H., Vemmos K., Koroboki E., Manios E., Vemmou A., Rodríguez-Campello A., Cuadrado-Godia E., Roquer J., Arnao V., Caso V., Paciaroni M., DIez-Tejedor E., Fuentes B., Pérez Lucas J., Arauz A., Ameriso S.F., Pertierra L., Gómez-Schneider M., Hawkes M.A., Bandini F., Chavarria Cano B., Iglesias Mohedano A.M., Garciá Pastor A., Gil-Núñez A., Putaala J., Tatlisumak T., Barboza M.A., Athanasakis G., Gioulekas F., Makaritsis K., Papavasileiou V. (2017)

Objective: To investigate whether the correlation of age and sex with the risk of recurrence and death seen in patients with previous ischemic stroke is also evident in patients with embolic stroke of undetermined source ...

Apolipoprotein E Polymorphism and Left Ventricular Failure in Beta-Thalassemia: A Multivariate Meta-Analysis

Dimou N.L., Pantavou K.G., Bagos P.G. (2017)

Apolipoprotein E (ApoE) is potentially a genetic risk factor for the development of left ventricular failure (LVF), the main cause of death in beta-thalassemia homozygotes. In the present study, we synthesize the results ...

Aspirin Versus Clopidogrel for Type 2 Diabetic Patients with First-Ever Noncardioembolic Acute Ischemic Stroke: Ten-Year Survival Data from the Athens Stroke Outcome Project

Milionis H., Ntaios G., Papavasileiou V., Spengos K., Manios E., Elisaf M., Vemmos K. (2017)

Background and objective Diabetes mellitus is associated with an increased risk of stroke and poor outcome following a stroke event. We assessed the impact of discharge treatment with aspirin versus clopidogrel on the ...

Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus

Medina-Gomez C., Kemp J.P., Dimou N.L., Kreiner E., Chesi A., Zemel B.S., Bønnelykke K., Boer C.G., Ahluwalia T.S., Bisgaard H., Evangelou E., Heppe D.H.M., Bonewald L.F., Gorski J.P., Ghanbari M., Demissie S., Duque G., Maurano M.T., Kiel D.P., Hsu Y.-H., Van Der Eerden B.C.J., Ackert-Bicknell C., Reppe S., Gautvik K.M., Raastad T., Karasik D., Van De Peppel J., Jaddoe V.W.V., Uitterlinden A.G., Tobias J.H., Grant S.F.A., Bagos P.G., Evans D.M., Rivadeneira F. (2017)

Bone mineral density is known to be a heritable, polygenic trait whereas genetic variants contributing to lean mass variation remain largely unknown. We estimated the shared SNP heritability and performed a bivariate GWAS ...

“Blame it on the Comorbidities”: A 5-Year Follow-Up of 53 Chronic Dialysis-Dependent Patients Who Underwent Cardiac Surgery

Deutsch O., Rippinger N., Spiliopoulos K., Eichinger W., Gansera B. (2016)

Objectives This study evaluates midterm survival rates and risk factors for mortality of chronic dialysis-dependent patients undergoing cardiac surgery. Methods Fifty-three dialysis-dependent patients (34 males, aged 67 ± ...

Continuing versus Stopping Prestroke Antihypertensive Therapy in Acute Intracerebral Hemorrhage: A Subgroup Analysis of the Efficacy of Nitric Oxide in Stroke Trial

Krishnan K., Scutt P., Woodhouse L., Adami A., Becker J.L., Cala L.A., Casado A.M., Chen C., Dineen R.A., Gommans J., Koumellis P., Christensen H., Collins R., Czlonkowska A., Lees K.R., Ntaios G., Ozturk S., Phillips S.J., Sprigg N., Szatmari S., Wardlaw J.M., Bath P.M., ENOS Investigators (2016)

Background and purpose More than 50% of patients with acute intracerebral hemorrhage (ICH) are taking antihypertensive drugs before ictus. Although antihypertensive therapy should be given long term for secondary prevention, ...

An electroglottographical analysis-based discriminant function model differentiating multiple sclerosis patients from healthy controls

Vavougios G.D., Doskas T., Konstantopoulos K. (2018)

Dysarthrophonia is a predominant symptom in many neurological diseases, affecting the quality of life of the patients. In this study, we produced a discriminant function equation that can differentiate MS patients from ...

Evaluation of respiratory parameters in finswimmers regarding gender, swimming style and distance

Stavrou V., Vavougios G., Karetsi E., Adam G., Daniil Z., Gourgoulianis K.I. (2018)

Aim: The purpose of our study was to investigate the differences in the finswimmers’ physiological characteristics, as far as gender, the swimming style and the different swimming distance are concerned. Methods: 52 ...

Failure in diagnosis and under-treatment of osteoporosis in elderly patients with fragility fractures

Bougioukli S., Κollia P., Koromila T., Varitimidis S., Hantes M., Karachalios T., Malizos Κ.Ν., Dailiana Z.H. (2019)

We evaluated whether osteoporosis is adequately managed and treated in patients suffering from fragility fractures. Factors that influenced osteoporosis diagnosis and treatment rates were also assessed. To this end, patients ...

Geoepidemiology, clinical manifestations and outcome of primary biliary cholangitis in Greece

Gatselis N.K., Zachou K., Lygoura V., Azariadis K., Arvaniti P., Spyrou E., Papadamou G., Koukoulis G.K., Dalekos G.N., Rigopoulou E.I. (2017)

Background & aims Primary biliary cholangitis (PBC) is a disease with rising prevalence and considerable geographical variation. To describe the prevalence, spatial and time distribution, baseline characteristics, response ...

Meta-Analysis Methods of Diagnostic Test Accuracy Studies

Dimou N., Bagos P. (2022)

Meta-analytic techniques are used to combine the results of different studies that have evaluated the accuracy of diagnostic tests. In this article, we present univariate and multivariate meta-analysis methods for a single ...

Multivariate methods for meta-analysis of genetic association studies

Dimou N.L., Pantavou K.G., Braliou G.G., Bagos P.G. (2018)

Multivariate meta-analysis of genetic association studies and genome-wide association studies has received a remarkable attention as it improves the precision of the analysis. Here, we review, summarize and present in a ...

Norovirus waterborne outbreak in Chalkidiki, Greece, 2015: Detection of GI.P2_GI.2 and GII.P16_GII.13 unusual strains

Tryfinopoulou K., Kyritsi M., Mellou K., Kolokythopoulou F., Mouchtouri V.A., Potamiti-Komi M., Lamprou A., Georgakopoulou Th., Hadjichristodoulou C. (2019)

Noroviruses, along with rotaviruses, are among the leading causes of gastroenteritis worldwide and novel strains are periodically emerging. In August 2015, an unusual increase of gastroenteritis cases occurred in a touristic ...

Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis

Weismüller T.J., Strassburg C.P., Trivedi P.J., Hirschfield G.M., Trivedi P.J., Bergquist A., Said K., Imam M., Lazaridis K.N., Juran B.D., Cheung A., Lindor K.D., Weismüller T.J., Lenzen H., Manns M.P., Ponsioen C.Y., Beuers U., Holm K., Naess S., Karlsen T.H., Schrumpf E., Boberg K.M., Gotthardt D., Rupp C., Färkkilä M.A., Jokelainen K., Marschall H.-U., Benito de Valle M., Thorburn D., Saffioti F., Weersma R.K., Fevery J., Mueller T., Chazouillères O., Schulze K., Schramm C., Almer S., Pereira S.P., Levy C., Mason A., Bowlus C.L., Floreani A., Halilbasic E., Trauner M., Yimam K.K., Milkiewicz P., Milkiewicz P., Huynh D.K., Pares A., Manser C.N., Dalekos G.N., Eksteen B., Invernizzi P., Berg C.P., Kirchner G.I., Sarrazin C., Zimmer V., Fabris L., Braun F., Marzioni M., Schramm C., Chapman R.W., Chapman R.W., Lindor K.D., Imam M., Lindor K.D., Naess S., Karlsen T.H., Schrumpf E., Boberg K.M., Hansen B.E., Hansen B.E., Hansen B.E., on behalf of the, International PSC Study Group (2017)

Background & Aims Primary sclerosing cholangitis (PSC) is an orphan hepatobiliary disorder associated with inflammatory bowel disease (IBD). We aimed to estimate the risk of disease progression based on distinct clinical ...

Prevalence and determinants of type 2 diabetes mellitus in a Greek adult population

Tsirona S., Katsaros F., Bargiota A., Polyzos S.A., Arapoglou G., Koukoulis G.N. (2016)

The prevalence of diabetes mellitus (DM) is increasing worldwide reaching epidemic proportions. The aim of the present study was to estimate the prevalence of DM in Thessaly, a large region of Central Greece, and to ...

Primary extranodal non Hodgkin's lymphoma of the head and neck in adults: A clinicopathological comparison between tonsillar and non tonsillar lymphomas

Economopoulos, T.; Fountzilas, G.; Kostourou, A.; Daniilidis, J.; Pavlidis, N.; Andreopoulou, H.; Nicolaou, A.; Papageorgiou, E.; Mellou, S.; Dervenoulas, J.; Stathakis, N. (1998)

Primary extranodal NHL of the head and neck (HN-NHL) accounts for 10-20% of all cases of NHL. Despite their frequency, the natural history and biological behaviour of these lymphomas is poorly understood. In this study we ...

Season of birth and multiple sclerosis: a systematic review and multivariate meta-analysis

Pantavou K.G., Bagos P.G. (2020)

Season of birth is considered to be associated with multiple sclerosis (MS) although some findings opposing to this assumption raise doubts about the seasonality pattern in MS births. The present work synthesizes the ...

Spiritual Well-Being and Associated Factors in End-Stage Renal Disease

Fradelos E.C. (2021)

People with CKD depend on religion and spirituality to deal with their chronic illness, and those are essential means of coping for those living with chronic diseases. The present study aims to evaluate ESRD patients' ...

TP53 mutations and protein immunopositivity may predict for poor outcome but also for trastuzumab benefit in patients with early breast cancer treated in the adjuvant setting

Fountzilas G., Giannoulatou E., Alexopoulou Z., Zagouri F., Timotheadou E., Papadopoulou K., Lakis S., Bobos M., Poulios C., Sotiropoulou M., Lyberopoulou A., Gogas H., Pentheroudakis G., Pectasides D., Koutras A., Christodoulou C., Papandreou C., Samantas E., Papakostas P., Kosmidis P., Bafaloukos D., Karanikiotis C., Dimopoulos M.-A., Kotoula V. (2016)

Background: We investigated the impact of PIK3CA and TP53 mutations and p53 protein status on the outcome of patients who had been treated with adjuvant anthracycline-taxane chemotherapy within clinical trials in the pre- ...