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Πλοήγηση ανά Θέμα "HARDY-WEINBERG EQUILIBRIUM"

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    • Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease 

      Maraganore, D. M.; de Andrade, M.; Elbaz, A.; Farrer, M. J.; Ioannidis, J. P. A.; Kruger, R.; Rocca, W. A.; Schneider, N. K.; Lesnick, T. G.; Lincoln, S. J.; Hulihan, M. M.; Aasly, J. O.; Ashizawa, T.; Chartier-Harlin, M. C.; Checkoway, H.; Ferrarese, C.; Hadjigeorgiou, G.; Hattori, N.; Kawakami, H.; Lambert, J. C.; Lynch, T.; Mellick, G. D.; Papapetropoulos, S.; Parsian, A.; Quattrone, A.; Riess, O.; Tan, E. K.; Van Broeckhoven, C.; Consortium, Geo-Pd (2006)
      Context Identification and replication of susceptibility genes for Parkinson disease at the population level have been hampered by small studies with potential biases. alpha-Synuclein (SNCA) has been one of the most promising ...

    • Meta-Analysis Methods 

      Trikalinos, T. A.; Salanti, G.; Zintzaras, E.; Ioannidis, J. P. A. (2008)
      Meta-analysis is the quantitative synthesis of information from several studies. It is applicable to a variety of study designs in genetics, from family-based linkage studies and population-based association studies to ...

    • Meta-Analysis of Family-Based and Case-Control Genetic Association Studies that Use the Same Cases 

      Bagos, P. G.; Dimou, N. L.; Liakopoulos, T. D.; Nikolopoulos, G. K. (2011)
      In many cases in genetic epidemiology, the investigators in an effort to control for different sources of confounding and simultaneously to increase the power perform a family-based and a population-based case-control study ...

    • A Multipoint Method for Meta-Analysis of Genetic Association Studies 

      Bagos, P. G.; Liakopoulos, T. D. (2010)
      Meta-analyses of genetic association studies are usually performed using a single polymorphism at a time, even though in many cases the individual studies report results from partially overlapping sets of polymorphisms. ...

    • Synthesis of genetic association studies for pertinent gene-disease associations requires appropriate methodological and statistical approaches 

      Zintzaras, E.; Lau, J. (2008)
      Objective: The aim of the study was to consider statistical and methodological issues affecting the results of meta-analysis of genetic association studies for pertinent gene-disease associations. Although the basic ...