Auflistung Nach Schlagwort "COMPLEX DISEASES"
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Endothelial NO synthase gene polymorphisms and hypertension - A meta-analysis
(2006)Studies investigated the association between endothelial NO synthase gene polymorphisms and hypertension-reported contradicted or nonconclusive results. A meta-analysis of 35 genetic association studies that examined the ... -
Maternal gene polymorphisms involved in folate metabolism and risk of Down syndrome offspring: a meta-analysis
(2007)Studies investigating the association between gene polymorphisms involved in homocysteine/folate metabolism and Down syndrome (DS) have reported contradictory or inconclusive results. A meta-analysis of 11 case-control ... -
Meta-Analysis Methods
(2008)Meta-analysis is the quantitative synthesis of information from several studies. It is applicable to a variety of study designs in genetics, from family-based linkage studies and population-based association studies to ... -
Methylenetetrahydrofolate reductase gene and susceptibility to breast cancer: a meta-analysis
(2006)The methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms have been linked to the risk of developing breast cancer. A meta-analysis of 18 case-control studies investigating the association between the C677T and ... -
The role of G196A polymorphism in the brain-derived neurotrophic factor gene in the cause of Parkinson's disease: a meta-analysis
(2005)The association between Parkinson's disease (PD) and the G196A polymorphism in the brain-derived neurotrophic factor (BDNF) gene has been investigated in several case-control studies, producing contradictory results: one ... -
Synthesis of genetic association studies for pertinent gene-disease associations requires appropriate methodological and statistical approaches
(2008)Objective: The aim of the study was to consider statistical and methodological issues affecting the results of meta-analysis of genetic association studies for pertinent gene-disease associations. Although the basic ...