Πλοήγηση ανά Συγγραφέα "Georgopoulou, U."
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A complex signaling network involving protein kinase CK2 is required for hepatitis C virus core protein-mediated modulation of the iron-regulatory hepcidin gene expression
Foka, P.; Dimitriadis, A.; Kyratzopoulou, E.; Giannimaras, D. A.; Sarno, S.; Simos, G.; Georgopoulou, U.; Mamalaki, A. (2014)Hepatitis C virus (HCV) infection is associated with hepatic iron overload and elevated serum iron that correlate to poor antiviral responses. Hepcidin (HAMP), a 25-aa cysteine-rich liver-specific peptide, controls iron ... -
Endocytosis of hepatitis C virus non-enveloped capsid-like particles induces MAPK-ERK1/2 signaling events
Katsarou, K.; Lavdas, A. A.; Tsitoura, P.; Serti, E.; Markoulatos, P.; Mavromara, P.; Georgopoulou, U. (2010)Although HCV is an enveloped virus, naked nucleocapsids have been reported in the serum of infected patients. The HCV core particle serves as a protective capsid shell for the viral genome and recombinant in vitro assembled ... -
Internal translation initiation stimulates expression of the ARF/core+1 open reading frame of HCV genotype 1b
Boumlic, A.; Vassilaki, N.; Dalagiorgou, G.; Kochlios, E.; Kakkanas, A.; Georgopoulou, U.; Markoulatos, P.; Orfanoudakis, G.; Mavromara, P. (2011)The hepatitis C virus possesses an alternative open reading frame overlapping the Core gene, whose products are referred to as Core+1 or alternative reading frame (ARF) or F protein(s). Extensive studies on genotype HCV-1 ...