Parcourir par sujet "microarray analysis"

Antimicrobial resistance genes in ESBL-producing escherichia coli isolates from animals in Greece

Athanasakopoulou Z., Reinicke M., Diezel C., Sofia M., Chatzopoulos D.C., Braun S.D., Reissig A., Spyrou V., Monecke S., Ehricht R., Tsilipounidaki K., Giannakopoulos A., Petinaki E., Billinis C. (2021)

The prevalence of multidrug resistant, extended spectrum -lactamase (ESBL)-producing Enterobacteriaceae is increasing worldwide. The present study aimed to provide an overview of the multidrug resistance phenotype and ...

Characterizing miRNA–lncRNA Interplay

Karagkouni D., Karavangeli A., Paraskevopoulou M.D., Hatzigeorgiou A.G. (2021)

Long noncoding RNAs (lncRNAs) are noncoding transcripts, usually longer than 200 nt, that constitute one of the largest and significantly heterogeneous RNA families. The annotation of lncRNAs and the characterization of ...

HPV infection in oropharyngeal squamous cell carcinomas: Correlation with tumor size

Gletsou E., Papadas T.A., Baliou E., Tsiambas E., Ragos V., Armata I.E., Metaxas G.E., Fotiades P.P. (2018)

Purpose: Human papillomavirus (HPV) is implicated in carcinogenesis of a variety of epithelia, including oropharyngeal and laryngeal. High risk (HR) HPV persistent infection in head and neck squamous cell carcinomas (HNSCC) ...

Investigating Molecular Determinants of Cancer Cell Resistance to Ionizing Radiation Through an Integrative Bioinformatics Approach

Toy H.I., Karakülah G., Kontou P.I., Alotaibi H., Georgakilas A.G., Pavlopoulou A. (2021)

Eradication of cancer cells through exposure to high doses of ionizing radiation (IR) is a widely used therapeutic strategy in the clinical setting. However, in many cases, cancer cells can develop remarkable resistance ...

Meta-analysis of gene expression profiles in preeclampsia

Vennou K.E., Kontou P.I., Braliou G.G., Bagos P.G. (2020)

Objective: Preeclampsia (PE) is a serious complication of pregnancy. It is considered a complex condition influenced by maternal genes, environmental factors and a deregulated immune response of the mother, but the etiology ...

Methods of analysis and meta-analysis for identifying differentially expressed genes

Kontou P.I., Pavlopoulou A., Bagos P.G. (2018)

Microarray approaches areÂ widely used high-throughput techniques to assess simultaneously the expression of thousands of genes under certain conditions and study the effects of certain treatments, diseases, and developmental ...

MRSA infections among patients in the emergency department: A European multicentre study

Bouchiat C., Curtis S., Spiliopoulou I., Bes M., Cocuzza C., Codita I., Dupieux C., Giormezis N., Kearns A., Laurent F., Molinos S., Musumeci R., Prat C., Saadatian-Elahi M., Tacconelli E., Tristan A., Schulte B., Vandenesch F., Monneuse O., de Francisco T., Casella P., Erbizzoni S., Melzi S., Oggioni D., Sala R., Calaresu E., Efthimia P., Markos M., Petinaki E., Schroeder W., on behalf of the ESCMID Study Group on Staphylococci and Staphylococcal Infections (ESGS) (2017)

Background: MRSA is a therapeutic concern worldwide, and a major agent of community-acquired skin and soft tissue infections (CA-SSTIs). While the US epidemiology of MRSA in CA-SSTIs is well described and reports the high ...

Multiple outcome meta-analysis of gene-expression data in inflammatory bowel disease

Vennou K.E., Piovani D., Kontou P.I., Bonovas S., Bagos P.G. (2020)

We performed a multivariate meta-analysis of microarray data in Crohn's disease (CD) and Ulcerative colitis (UC), which are the main forms of inflammatory bowel disease (IBD). They share similar symptoms but differ in the ...

Network analysis in aged C. elegans reveals candidate regulatory genes of ageing

Aktypi F., Papaevgeniou N., Voutetakis K., Chatziioannou A., Grune T., Chondrogianni N. (2021)

Ageing is a biological process guided by genetic and environmental factors that ultimately lead to adverse outcomes for organismal lifespan and healthspan. Determination of molecular pathways that are affected with age and ...

Poly(A)-specific ribonuclease and Nocturnin in squamous cell lung cancer: Prognostic value and impact on gene expression

Maragozidis P., Papanastasi E., Scutelnic D., Totomi A., Kokkori I., Zarogiannis S.G., Kerenidi T., Gourgoulianis K.I., Balatsos N.A.A. (2015)

Background: Lung cancer is the leading cause of cancer mortality worldwide, mainly due to late diagnosis, poor prognosis and tumor heterogeneity. Thus, the need for biomarkers that will aid classification, treatment and ...

Reporting on the Role of miRNAs and Affected Pathways on the Molecular Backbone of Ovarian Insufficiency: A Systematic Review and Critical Analysis Mapping of Future Research

Rapani A., Nikiforaki D., Karagkouni D., Sfakianoudis K., Tsioulou P., Grigoriadis S., Maziotis E., Pantou A., Voutsina A., Pantou A., Koutsilieris M., Hatzigeorgiou A., Pantos K., Simopoulou M. (2021)

Ovarian insufficiency is identified as a perplexing entity in the long list of pathologies impairing fertility dynamics. The three distinct classifications of ovarian insufficiency are poor ovarian response, premature ...

Transcriptome Analysis Identifies Immune Markers Related to Visceral Leishmaniasis Establishment in the Experimental Model of BALB/c Mice

Agallou M., Athanasiou E., Kammona O., Tastsoglou S., Hatzigeorgiou A.G., Kiparissides C., Karagouni E. (2019)

Visceral leishmaniasis (VL) caused by Leishmania donovani and L. infantum is a potentially fatal disease. To date there are no registered vaccines for disease prevention despite the fact that several vaccines are in ...