Parcourir par sujet "Cancer"
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Advances in Ultrasound Technology in Oncologic Urology
(2009)Continuous innovations and clinical research in ultrasound (US) technology have upgraded the position of US in the imaging armamentarium of urologists. In particular, contrast-enhanced US and sonoelastography seem to be ... -
Alterations of microRNAs in solid cancers and their prognostic value
(2010)MicroRNAs (miRNAs) are evolutionarily conserved, naturally abundant, small, regulatory non-coding RNAs that inhibit gene expression at the post-transcriptional level in a sequence-specific manner. Each miRNA represses the ... -
Assessing the Quality of Reporting of Observational Studies in Cancer
(2010)PURPOSE: The vast majority of epidemiological studies in cancer are observational. However, inadequate reporting of the published observational studies (OS) may restrict the generalizability and credibility of study results. ... -
Colocteral cancer management and prevention policies in Greece
(2010)Despite lower cancer mortality rates in Greece compared to other European countries, colorectal cancer (CRC) is the third most important cause of cancer mortality. Given the significant economic and societal impact of CRC ... -
Development and validation of a reversed-phase HPLC method for CYP1A2 phenotyping by use of a caffeine metabolite ratio in saliva
(2015)CYP1A2 is important for metabolizing various clinically used drugs. Phenotyping of CYP1A2 may prove helpful for drug individualization therapy. Several HPLC methods have been developed for quantification of caffeine ... -
Dichloroacetate at therapeutic concentration alters glucose metabolism and induces regulatory t-cell differentiation in alloreactive human lymphocytes
(2013)Background: Most cancer cells rely on aerobic glycolysis. Dichloroacetate (DCA) inhibits aerobic glycolysis and is a promising relatively nontoxic anticancer compound. However, rapidly proliferating effector T-cells also ... -
Dietary habits of Greek primary school children
(2007)The purpose of this study was to assess Greek primary (1st to 6th grade) school children's dietary habits and the factors influencing them. Our results show that children know the value of different foods. The socio-economic ... -
Efficient Bayesian Expert Models for Fever in Neutropenia and Fever in Neutropenia with Bacteremia
(2020)Bayesian expert models are very efficient solutions since they can encapsulate in a mathematical consistent way, certain and uncertain knowledge, as well as preferences strategies and policies. Furthermore, the Bayesian ... -
Isolation of hypoxia-inducible factor 1 (HIF-1) inhibitors from frankincense using a molecularly imprinted polymer
(2011)Hypoxia-Inducible Factor 1 (HIF-1), a transcriptional activator, is highly involved in the pathology of cancer. Inhibition of HIF-1 retards tumor growth and enhances treatment efficiency when used in combination with chemo- ... -
Sex hormone binding globulin of the plasma: Towards understanding of a new regulatory system in steroid hormone action
(1999)Sex hormone binding globulin (SHBG) is a protein that circulates in the plasma of many species and binds with high affinity to sex steroids in the human and primates, while it is androgen-binding protein in many animals ... -
Shikonin-loaded liposomes as a new drug delivery system: Physicochemical characterization and in vitro cytotoxicity
(2011)Alkannin and shikonin are naturally occurring hydroxynaphthoquinones with a well-established spectrum of wound healing, antimicrobial, anti-inflammatory, and antioxidant activities. Recently, extensive scientific effort ... -
Smart polymersomes and hydrogels from polypeptide-based polymer systems through α-amino acid N-carboxyanhydride ring-opening polymerization. From chemistry to biomedical applications
(2018)The synthesis of smart stimuli-responsive polymeric materials for nanomedicine applications has attracted the interest of a large number of scientists that focuses on the effective encapsulation of pharmaceutical compounds ... -
Truncation and optimisation of peptide inhibitors of cyclin-dependent kinase 2-cyclin A through structure-guided design
(2009)The cyclin-dependent kinase 2-cyclin A complex is an important regulator of the DNA-synthesis phase of the mammalian cell cycle, which is frequently deregulated in cancer. Rather than blocking the ATP-binding site of the ...