Parcourir par auteur "Antoniadi, G."
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About the Role of Prohepcidin as an Indicator of Iron Status in Dialysis Patients
Eleftheriadis, T.; Liakopoulos, V.; Kartsios, C.; Antoniadi, G.; Zarogiannis, S.; Markala, D.; Stefanidis, I. (2008) -
Alpha-Tocopherol Administration Decreases Serum Urate Levels in Hemodialysis Patients
Eleftheriadis, T.; Antoniadi, G.; Liakopoulos, V.; Stefanidis, I. (2010) -
Arginase type I as a marker of coronary heart disease in hemodialysis patients
Eleftheriadis, T.; Liakopoulos, V.; Antoniadi, G.; Stefanidis, I.; Galaktidou, G. (2011)Cardiovascular disease, and mainly coronary heart disease (CHD), is the leading cause of death in hemodialysis (HD) patients. Non-traditional risk factors may play an important role in this population. Arginase is known ... -
Can a single inflammatory marker adequately predict resistance to erythropoiesis-stimulating agents in hemodialysis patients?
Eleftheriadis, T.; Antoniadi, G.; Liakopoulos, V.; Stefanidis, I. (2013) -
CD8+T-cell auto-reactivity is dependent on the expression of the immunoproteasome subunit LMP7 in exposed to lipopolysaccharide antigen presenting cells and epithelial target cells
Eleftheriadis, T.; Pissas, G.; Antoniadi, G.; Liakopoulos, V.; Stefanidis, I. (2013)Proteasome generates peptides for presentation to CD8+ T-cells by antigen presenting cells (APCs) and peripheral cells. Inflammation alters proteasome to immunoproteasome, producing a different pool of peptides. The effect ... -
Damage-associated molecular patterns derived from mitochondria may contribute to the hemodialysis-associated inflammation
Eleftheriadis, T.; Pissas, G.; Antoniadi, G.; Liakopoulos, V.; Stefanidis, I. (2014)Inflammation is common in hemodialysis (HD) patients. Mitochondrial damage-associated molecular patterns (DAMPs) are released during cell necrosis or apoptosis and induce inflammation. Cell apoptosis is increased in HD ... -
Dichloroacetate at therapeutic concentration alters glucose metabolism and induces regulatory t-cell differentiation in alloreactive human lymphocytes
Eleftheriadis, T.; Pissas, G.; Karioti, A.; Antoniadi, G.; Antoniadis, N.; Liakopoulos, V.; Stefanidis, I. (2013)Background: Most cancer cells rely on aerobic glycolysis. Dichloroacetate (DCA) inhibits aerobic glycolysis and is a promising relatively nontoxic anticancer compound. However, rapidly proliferating effector T-cells also ... -
Differential diagnosis of hyperkalemia: an update to a complex problem
Eleftheriadis, T.; Leivaditis, K.; Antoniadi, G.; Liakopoulos, V. (2012)Hyperkalemia is a relative common and sometimes life threatening electorlyte disorder. Although its symptomatic treatment is relatively easy, since precise therapeutic algorithms are available, its differential diagnosis ... -
Disturbances of acquired immunity in hemodialysis patients
Eleftheriadis, T.; Antoniadi, G.; Liakopoulos, V.; Kartsios, C.; Stefanidis, I. (2007)Acquired immunity disturbances in hemodialysis (HD) patients are many and diverse. They are caused by uremia per se, the HD procedure, chronic renal failure complications, and therapeutic interventions for their treatment. ... -
Does hepcidin affect erythropoiesis in hemodialysis patients?
Eleftheriadis, T.; Kartsios, C.; Liakopoulos, V.; Antoniadi, G.; Ditsa, M.; Papadopoulos, C.; Anifandis, G.; Skirta, A.; Markala, D.; Stefanidis, I. (2006)Introduction: Prohepcidin is the precursor of hepcidin, a liver-derived peptide involved in iron metabolism by blocking its intestinal absorption and its release by the reticuloendothelial system. Iron overload and ... -
Effect of 1-year oral alpha-tocopherol administration on anticardiolipin antibodies in hemodialysis patients
Antoniadi, G.; Eleftheriadis, T.; Liakopoulos, V.; Kakasi, E.; Vayonas, G.; Kortsaris, A.; Vargemezis, V. (2005)Background. Anticardiolipin antibodies (ACA) have been related to an increased incidence of thrombotic episodes and atherosclerosis progression. ACA levels are elevated in hemodialysis (HD) patients. Atheroembolic episodes ... -
Factors affecting effectiveness of vaccination against hepatitis B virus in hemodialysis patients
Eleftheriadis, T.; Pissas, G.; Antoniadi, G.; Liakopoulos, V.; Stefanidis, I. (2014)Hepatitis B virus (HBV) is a major global health problem. Despite the success of the general measures against blood transmitted infections in hemodialysis (HD) units, the prevalence of HBV infection among the HD patients ... -
Ferroportin in monocytes of hemodialysis patients and its associations with hepcidin, inflammation, markers of iron status and resistance to erythropoietin
Eleftheriadis, T.; Pissas, G.; Remoundou, M.; Filippidis, G.; Antoniadi, G.; Oustampasidou, N.; Liakopoulos, V.; Stefanidis, I. (2014)Disturbed iron homeostasis contributes to resistance to recombinant human erythropoietin (rHuEpo) in hemodialysis (HD) patients. Increased hepcidin, which downregulates the iron exporter ferroportin, has been incriminated. ... -
Increased Plasma Angiogenin Level is Associated and May Contribute to Decreased T-Cell Zeta-Chain Expression in Hemodialysis Patients
Eleftheriadis, T.; Kartsios, C.; Pissas, G.; Liakopoulos, V.; Antoniadi, G.; Galaktidou, G.; Stefanidis, I. (2013)Hemodialysis (HD) patients are characterized by impaired T-cell function at least in part because of T-cell zeta-chain downregulation due to inflammation. Angiogenin responds as an acute phase reactant, is increased in HD ... -
Increased visfatin in hemodialysis patients is associated with decreased demands for recombinant human erythropoietin
Eleftheriadis, T.; Pissas, G.; Remoundou, M.; Antoniadi, G.; Liakopoulos, V.; Stefanidis, I. (2013)Background: Studies detected an association between visfatin and markers of iron metabolism in patients with insulin resistance. In this study, such a relation was evaluated in hemodialysis (HD) patients. Also relations ... -
Indoleamine 2,3-dioxygenase depletes tryptophan, activates general control non-derepressible 2 kinase and down-regulates key enzymes involved in fatty acid synthesis in primary human CD4+ T cells
Eleftheriadis, T.; Pissas, G.; Antoniadi, G.; Liakopoulos, V.; Stefanidis, I. (2015)Indoleamine 2,3-dioxygenase (IDO) is expressed in antigen-presenting cells and exerts immunosuppressive effects on CD4+ T cells. One mechanism is through the inhibition of aerobic glycolysis. Another prerequisite for T-cell ... -
Indoleamine 2,3-dioxygenase increases p53 levels in alloreactive human T cells, and both indoleamine 2,3-dioxygenase and p53 suppress glucose uptake, glycolysis and proliferation
Eleftheriadis, T.; Pissas, G.; Antoniadi, G.; Spanoulis, A.; Liakopoulos, V.; Stefanidis, I. (2014)Indoleamine 2,3-dioxygenase (IDO) suppresses adaptive immunity by inhibiting T-cell proliferation and altering glucose metabolism. The tumor suppressor p53 also alters these cellular processes with similar results. The ... -
The Indoleamine 2,3-dioxygenase Inhibitor 1-methyl-tryptophan Suppresses Mitochondrial Function, Induces Aerobic Glycolysis and Decreases Interleukin-10 Production in Human Lymphocytes
Eleftheriadis, T.; Pissas, G.; Karioti, A.; Antoniadi, G.; Liakopoulos, V.; Dafopoulou, K.; Pournaras, S.; Koukoulis, G.; Stefanidis, I. (2012)Background: Indoleamine 2,3-dioxygenase (IDO) suppresses adaptive immunity. It is known that IDO induces T-cell differentiation to regulatory T-cells (Treg) through tryptophan depletion and/or kynurenine pathway products. ... -
Indoleamine 2,3-dioxygenase is increased in hemodialysis patients and affects immune response to hepatitis B vaccination
Eleftheriadis, T.; Liakopoulos, V.; Antoniadi, G.; Stefanidis, I.; Galaktidou, G. (2011)Background: Acquired immunity is impaired in hemodialysis (HD) patients. Indoleamine 2,3-dioxygenase (IDO) is inducible by inflammation and through tryptophan depletion and generation of kynurenine pathway products suppresses ... -
Infections in hemodialysis: a concise review - Part 1: bacteremia and respiratory infections
Eleftheriadis, T.; Liakopoulos, V.; Leivaditis, K.; Antoniadi, G.; Stefanidis, I. (2011)Hemodialysis (HD) patients are particularly predisposed to infections. It seems that the HD procedure per se as well as disturbances in both innate and adaptive immunity significantly contribute to this susceptibility. ...