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Πλοήγηση ανά Θέμα "regulatory T lymphocyte"

Αποτελέσματα 21-27 από 27

    • The role of B cells in the pathogenesis of systemic sclerosis 

      Sakkas L.I., Bogdanos D.P. (2016)
      Systemic sclerosis (SSc) is characterized by extensive collagen deposition, microvasculopathy and autoantibodies. All three features can be promoted by activation of T cells and B cells. T cells are of Th2 type producing ...

    • The role of flavonoids in inhibiting Th17 responses in inflammatory arthritis 

      Kelepouri D., Mavropoulos A., Bogdanos D.P., Sakkas L.I. (2018)
      Flavonoids have been considered powerful anti-inflammatory agents, and their exact immunomodulatory action as therapeutic agents in autoimmune diseases has started to emerge. Their role in the manipulation of immunoregulation ...

    • The role of invariant NKT in autoimmune liver disease: Can Vitamin D Act as an Immunomodulator? 

      Smyk D.S., Mavropoulos A., Mieli-Vergani G., Vergani D., Lenzi M., Bogdanos D.P. (2018)
      Natural killer T (NKT) cells are a distinct lineage of T cells which express both the T cell receptor (TCR) and natural killer (NK) cell markers. Invariant NKT (iNKT) cells bear an invariant TCR and recognize a small variety ...

    • The second greek–israeli symposium on autoimmunity and rheumatology: Success through synergy 

      Sakkas L.I., Bogdanos D.P., Boumpas D., Mamouris Z., Gkoutzourelas A., Mavropoulos A., Tsouris Z., Liossis S.-N., Daoussis D., Vasilopoulos D., Tektonidou M., Tzioufas A., Efthymiou G., Dardiotis E., Kitas G., Sharif K., Blank M., Karussis D., Rimar D., Slobodin G., Porat-Katz B.-S., Vadasz Z., Amital H., Toubi E., Shoenfeld Y. (2019)
      [No abstract available]

    • Systemic sclerosis: New evidence re-enforces the role of B cells 

      Sakkas L.I., Bogdanos D.P. (2016)
      Systemic sclerosis (SSc) is characterized by widespread fibrosis, microangiopathy (vasospasms and stenosis), and formation of autoantibodies. T cell activation has been shown to contribute to fibrosis and microvasculopathy ...

    • A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis 

      Madireddy L., Patsopoulos N.A., Cotsapas C., Bos S.D., Beecham A., McCauley J., Kim K., Jia X., Santaniello A., Caillier S.J., Andlauer T.F.M., Barcellos L.F., Berge T., Bernardinelli L., Martinelli-Boneschi F., Booth D.R., Briggs F., Celius E.G., Comabella M., Comi G., Cree B.A.C., D’Alfonso S., Dedham K., Duquette P., Efthimios D., Esposito F., Fontaine B., Gasperi C., Goris A., Dubois B., Gourraud P.-A., Hadjigeorgiou G., Haines J., Hawkins C., Hemmer B., Hintzen R., Horakova D., Isobe N., Kalra S., Kira J.-I., Khalil M., Kockum I., Lill C.M., Lincoln M.R., Luessi F., Martin R., Oturai A., Palotie A., Pericak-Vance M.A., Henry R., Saarela J., Ivinson A., Olsson T., Taylor B.V., Stewart G.J., Harbo H.F., Compston A., Hauser S.L., Hafler D.A., Zipp F., De Jager P., Sawcer S., Oksenberg J.R., Baranzini S.E., International Multiple Sclerosis Genetics Consortium (2019)
      Genome-wide association studies (GWAS) have identified more than 50,000 unique associations with common human traits. While this represents a substantial step forward, establishing the biology underlying these associations ...

    • Tryptophan-kynurenine profile in pediatric autoimmune hepatitis 

      Lytton S.D., Osiecki M., MałgorzataWoźniak, Cukrowska B., Wierzbicka A., Goliszek M., Socha P., Janczyk W., Dayanakli D., Abendroth D., Kramp S., Fechner K., Scheper T., Mahler M., Bentow C., Bogdanos D., Fuchs D., Woynarowski M. (2019)
      The impairment of regulatory T cells (Tregs) is a characteristic feature of autoimmune hepatitis (AIH), and the degradation of tryptophan (Trp) to kynurenine (Kyn), by gamma interferon-induced indoleamine-2,3-dioxygenase-1 ...