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Parcourir par sujet "genetic marker"

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    • Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes 

      Ntoumou E., Tzetis M., Braoudaki M., Lambrou G., Poulou M., Malizos K., Stefanou N., Anastasopoulou L., Tsezou A. (2017)
      Background: MicroRNAs (miRNAs) in circulation have emerged as promising biomarkers. In this study, we aimed to identify a circulating miRNA signature for osteoarthritis (OA) patients and in combination with bioinformatics ...

    • Validation study of genetic biomarkers of response to TNF inhibitors in rheumatoid arthritis 

      Lopez-Rodriguez R., Perez-Pampin E., Marquez A., Blanco F.J., Joven B., Carreira P., Ferrer M.A., Caliz R., Valor L., Narvaez J., Cañete J.D., Del Carmen Ordoñez M., Manrique-Arija S., Vasilopoulos Y., Balsa A., Pascual-Salcedo D., Moreno-Ramos M.J., Alegre-Sancho J.J., Navarro-Sarabia F., Moreira V., Garcia-Portales R., Raya E., Magro-Checa C., Martin J., Gomez-Reino J.J., Gonzalez A. (2018)
      Genetic biomarkers are sought to personalize treatment of patients with rheumatoid arthritis (RA), given their variable response to TNF inhibitors (TNFi). However, no genetic biomaker is yet sufficiently validated. Here, ...