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Πλοήγηση ανά Θέμα "disease severity"

Αποτελέσματα 21-40 από 241

    • Association of p16 (CDKN2A) polymorphisms with the development of HPV16-related precancerous lesions and cervical cancer in the Greek population 

      Tsakogiannis D., Moschonas G.D., Bella E., Kyriakopoulou Z., Amoutzias G.D., Dimitriou T.G., Kottaridi C., Markoulatos P. (2018)
      The tumor suppressor protein p16 plays a fundamental role in cell cycle regulation and exerts a protective effect against tumor growth. Two different polymorphisms at positions 540 and 580 at the 3′UTR of exon 3 of p16 ...

    • Atrial fibrillation and cognitive function in patients with heart failure: a systematic review and meta-analysis 

      Myserlis P.G., Malli A., Kalaitzoglou D.K., Kalaitzidis G., Miligkos M., Kokkinidis D.G., Kalogeropoulos A.P. (2017)
      Cognitive impairment and dementia are established complications of heart failure (HF) in adult patients and impair medication adherence and self-care. Atrial fibrillation (AF) is suggested to play an independent role in ...

    • Atrial Fibrillation Is Associated with Cognitive Impairment, All-Cause Dementia, Vascular Dementia, and Alzheimer’s Disease: a Systematic Review and Meta-Analysis 

      Papanastasiou C.A., Theochari C.A., Zareifopoulos N., Arfaras-Melainis A., Giannakoulas G., Karamitsos T.D., Palaiodimos L., Ntaios G., Avgerinos K.I., Kapogiannis D., Kokkinidis D.G. (2021)
      Background: Atrial fibrillation (AF) is a risk factor for cognitive impairment and dementia in patients with stroke history. However, the association between AF and cognitive impairment in broader populations is less clear. ...

    • Atrial high-rate episode duration thresholds and thromboembolic risk: A systematic review and meta-analysis 

      Sagris D., Georgiopoulos G., Pateras K., Perlepe K., Korompoki E., Milionis H., Tsiachris D., Chan C., Lip G.Y.H., Ntaios G. (2021)
      BACKGROUND: Available evidence supports an association between atrial high-rate episode (AHRE) burden and thromboembolic risk, but the necessary extent and duration of AHREs to increase the thromboembolic risk remain to ...

    • Autism spectrum disorder, anxiety and severe depression in a male patient with deletion and duplication in the 21q22.3 region: A case report 

      Orru S., Papoulidis I., Siomou E., Papadimitriou D.T., Sotiriou S., Nikolaidis P., Eleftheriades M., Papanikolaou E., Thomaidis L., Manolakos E. (2019)
      In this report, a patient carrying a 650 kb deletion and a 759 kb duplication of chromosomal 21q22.3 region was described. Facial dysmorphic features, hypotonia, short stature, learning impairment, autism spectrum disorder, ...

    • Baseline neurofilament levels in cerebrospinal fluid do not correlate with long-term prognosis in multiple sclerosis 

      Aloizou A.-M., Liampas I., Provatas A., Brotis A., Siokas V., Bakritzis C., Liakos P., Tsouris Z., Dardiotis E. (2022)
      Background: Multiple Sclerosis (MS) is the most common autoimmune disease of the central nervous system. Up to this day, no single accurate prognostic biomarker has been established in this disease. Neurofilaments are ...

    • Bloodstream infections and sepsis in Greece: Over-time change of epidemiology and impact of de-escalation on final outcome 

      Koupetori, M.; Retsas, T.; Antonakos, N.; Vlachogiannis, G.; Perdios, I.; Nathanail, C.; Makaritsis, K.; Papadopoulos, A.; Sinapidis, D.; Giamarellos-Bourboulis, E. J.; Pneumatikos, I.; Gogos, C.; Armaganidis, A.; Paramythiotou, E. (2014)
      Background: Choice of empirically prescribed antimicrobials for sepsis management depends on epidemiological factors. The epidemiology of sepsis in Greece was studied in two large-periods.Methods: Sepsis due to bloodstream ...

    • Brain diseases in changing climate 

      Ruszkiewicz J.A., Tinkov A.A., Skalny A.V., Siokas V., Dardiotis E., Tsatsakis A., Bowman A.B., da Rocha J.B.T., Aschner M. (2019)
      Climate change is one of the biggest and most urgent challenges for the 21st century. Rising average temperatures and ocean levels, altered precipitation patterns and increased occurrence of extreme weather events affect ...

    • Caffeine metabolism in liver cirrhosis 

      Begas, E.; Asprodini, E. K.; Papakosta, S.; Maglaras, L.; Benakis, A.; Dalekos, G. (2005)
      Caffeine is metabolized primarily by CYP1A2. Several methods have been developed for the in vivo assessment of CYP1A2 activity using caffeine as a probe drug (2). These methods include the determination of caffeine clearance ...

    • Carotid artery plaque echomorphology and its association with histopathologic characteristics 

      Spanos K., Tzorbatzoglou I., Lazari P., Maras D., Giannoukas A.D. (2018)
      Objective: The aim of the study was to determine the association of ultrasonic texture features (severity of stenosis, grey scale median, plaque area, juxtaluminal black area [JBA], and discrete white areas) previously ...

    • Changes in dynamic lung mechanics after lung volume reduction coil treatment of severe emphysema 

      Makris D., Leroy S., Pradelli J., Benzaquen J., Guenard H., Perotin J.-M., Zakynthinos S., Zakynthinos E., Deslee G., Marquette C.H. (2018)
      We assessed the relationships between changes in lung compliance, lung volumes and dynamic hyperinflation in patients with emphysema who underwent bronchoscopic treatment with nitinol coils (coil treatment) (n=11) or ...

    • Characteristics and outcomes of Embolic Stroke of Undetermined Source according to stroke severity 

      Leventis I., Perlepe K., Sagris D., Sirimarco G., Strambo D., Georgiopoulos G., Eskandari A., Karagkiozi E., Vemmou A., Koroboki E., Manios E., Makaritsis K., Vemmos K., Michel P., Ntaios G. (2020)
      Background and aims: Patients with embolic strokes of undetermined source (ESUS) usually present with mild symptoms. We aimed to compare the baseline characteristics between mild and severe ESUS, identify predictors for ...

    • Children with psoriasis and COVID-19: factors associated with an unfavourable COVID-19 course, and the impact of infection on disease progression (Chi-PsoCov registry) 

      Zitouni J., Bursztejn A.-C., Belloni Fortina A., Beauchet A., Di Lernia V., Lesiak A., Thomas J., Topkarci Z., Murashkin N., Brzezinski P., Torres T., Chiriac A., Luca C., McPherson T., Akinde M., Maruani A., Epishev R., Vidaurri de la Cruz H., Luna P.C., Amy de la Bretêque M., Lasek A., Bourrat E., Bachelerie M., Mallet S., Steff M., Bellissen A., Neri I., Zafiriou E., van den Reek J.M.P.A., Sonkoly E., Mahil S.K., Smith C.H., Flohr C., Bachelez H., Mahé E., the Groupe de Recherche sur le Psoriasis (GrPso) of the Societe Francaise de Dermatologie, the Groupe de recherche de la Societe Francaise de Dermatologie Pediatrique (GR SFDP), the PsoProtect study group, the British Society of Paediatric Dermatology (BPSD), and the Societa Italiana di Dermatologia Pediatrica (S.I.Der.P.) (2022)
      Background: The COVID-19 pandemic has raised questions regarding the management of chronic skin diseases, especially in patients on systemic treatments. Data concerning the use of biologics in adults with psoriasis are ...

    • Circulating suPAR associates with severity and in-hospital progression of COVID-19 

      Chalkias A., Skoulakis A., Papagiannakis N., Laou E., Tourlakopoulos K., Pagonis A., Michou A., Ntalarizou N., Mermiri M., Ragias D., Bernal-Morell E., Cebreiros López I., García de Guadiana-Romualdo L., Eugen-Olsen J., Gourgoulianis K., Pantazopoulos I., Chalkias A., Skoulakis A., Laou E., Michou A., Ntalarizou N., Mermiri M., Ragias D., Tourlakopoulos K., Pagonis A., Gourgoulianis K., Pantazopoulos I., Papagiannakis N., Kampolis C., García de Guadiana-Romualdo L., Albaladejo-Otón M.D., Rodríguez Mulero M.D., Galindo Martínez M., Hernández Olivo M., Campos Rodríguez V., Cebreiros López I., Arnaldos Carrillo M., Noguera Velasco J.A., Pascual Figal D.A., Bernal-Morell E., Alcaraz García A., Alcaraz García M.J., Martínez Martínez M., Esteban-Torrella P., Sancho-Rodríguez N., Eugen-Olsen J., for the SPARCOL Investigators (2022)
      Background: COVID-19 disease progression is characterized by hyperinflammation and risk stratification may aid in early aggressive treatment and advanced planning. The aim of this study was to assess whether suPAR and other ...

    • Classification of COPD patients and compliance to recommended treatment in Greece according to GOLD 2017 report: the RELICO study 

      Tzanakis N., Koulouris N., Dimakou K., Gourgoulianis K., Kosmas E., Chasapidou G., Konstantinidis A., Kyriakopoulos C., Kontakiotis T., Rapti A., Gaga M., Kalafatakis K., Kostikas K. (2021)
      Background: Chronic obstructive pulmonary disease (COPD) is a multifactorial clinical condition, characterized by chronic progressive (or worsening) respiratory symptoms, structural pulmonary abnormalities, and impaired ...

    • Clinical and financial burden of active lupus in Greece: A nationwide study 

      Bertsias G., Karampli E., Sidiropoulos P., Gergianaki I., Drosos A., Sakkas L., Garyfallos A., Tzioufas A., Vassilopoulos D., Tsalapaki C., Sfikakis P., Panopoulos S., Athanasakis K., Perna A., Psomali D., Kyriopoulos J., Boumpas D.T. (2016)
      Analyses of the medical and economic burden of chronic disorders such as systemic lupus erythematosus (SLE) are valuable for clinical and health policy decisions. We performed a chart-based review of 215 adult SLE patients ...

    • Clinical and laboratory characteristics, epidemiology, and outcomes of murine typhus: A systematic review 

      Tsioutis C., Zafeiri M., Avramopoulos A., Prousali E., Miligkos M., Karageorgos S.A. (2017)
      Murine or endemic typhus, a febrile disease caused by Rickettsia typhi, is often misdiagnosed due to its non-specific presentation. We sought to evaluate all available evidence in the literature regarding the clinical and ...

    • Clinical and virological heterogeneity of hepatitis delta in different regions world-wide: The Hepatitis Delta International Network (HDIN) 

      Wranke A., Pinheiro Borzacov L.M., Parana R., Lobato C., Hamid S., Ceausu E., Dalekos G.N., Rizzetto M., Turcanu A., Niro G.A., Lubna F., Abbas M., Ingiliz P., Buti M., Ferenci P., Vanwolleghem T., Hayden T., Dashdorj N., Motoc A., Cornberg M., Abbas Z., Yurdaydin C., Manns M.P., Wedemeyer H., Hardtke S., Serrano B., Wöbse M., Heidrich B., Muche M., Gatselis N., Zachou K., Ho E., Smedile A., Fontana R., Gish R., Obretin D., Stern R., the Hepatitis Delta International Network (2018)
      Background & Aims: Chronic hepatitis D (delta) is a major global health burden. Clinical and virological characteristics of patients with hepatitis D virus (HDV) infection and treatment approaches in different regions ...

    • Clinical phenotype in patients with α-synuclein Parkinson's disease living in Greece in comparison with patients with sporadic Parkinson's disease 

      Papapetropoulos, S.; Paschalis, C.; Athanassiadou, A.; Papadimitriou, A.; Ellul, J.; Polymeropoulos, M. H.; Papapetropoulos, Th (2001)
      Objective - An Ala53Thr mutation of the α-synuclein gene has been recently identified as a rare cause of autosomal Parkinson's disease (PD). The clinical characteristics of 15 patients with PD living in Greece with the ...

    • Clinical reasoning in patients with lower limb tendinopathy a rehabilitation framework 

      Patselas T., Spanos S. (2020)
      Tendinopathy is an “umbrella” term that indicates a load-related, non-rupture injury of the tendon. The etiology of tendinopathy can be considered as multifactorial, and its identification and management have proved to be ...