Πλοήγηση ανά Συγγραφέα "Zachou, K."
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Clinical significance of organ- and non-organ-specific autoantibodies on the response to anti-viral treatment of patients with chronic hepatitis C
Gatselis, N. K.; Georgiadou, S. P.; Koukoulis, G. K.; Tassopoulos, N.; Zachou, K.; Liaskos, C.; Hatzakis, A.; Dalekos, G. N. (2006)Background: Development of organ- and non-organ-specific autoantibodies has been reported in hepatitis C virus patients treated with interferon-α plus/minus ribavirin. Aims: To address whether prevalence and the titre of ... -
CLINICAL SIGNIFICANCE OF THE FLUCTUATION OF PRIMARY BILIARY CIRRHOSIS-RELATED AUTOANTIBODIES DURING THE COURSE OF THE DISEASE
Gatselis, N. K.; Zachou, K.; Norman, G. L.; Gabeta, S.; Koukoulis, G. K.; Dalekos, G. N. (2012) -
Clinical significance of the fluctuation of primary biliary cirrhosis-related autoantibodies during the course of the disease
Gatselis, N. K.; Zachou, K.; Norman, G. L.; Gabeta, S.; Papamichalis, P.; Koukoulis, G. K.; Dalekos, G. N. (2013)Primary biliary cirrhosis (PBC) is a chronic cholestatic disease characterized by the presence of antimitochondrial antibodies (AMA). PBC-specific antinuclear antibodies (ANA) have been characterized and associated with ... -
Clinical, laboratory and demographic characteristics of autoimmune hepatitis type 1 (AIH-1) in Central Greece
Dalekos, G. N.; Makri, E. D.; Zachou, K.; Liaskos, C.; Pliaka, A.; Papadamou, G.; Patsiaoura, K. (2001) -
Comparison of simplified score with the revised original score for the diagnosis of autoimmune hepatitis: A new or a complementary diagnostic score?
Gatselis, N. K.; Zachou, K.; Papamichalis, P.; Koukoulis, G. K.; Gabeta, S.; Dalekos, G. N.; Rigopoulou, E. I. (2010)Background and aims: The International Autoimmune Hepatitis Group developed a simplified score for autoimmune hepatitis. We assessed this "new scoring system" and compared it with the International Autoimmune Hepatitis ... -
Cross-genotype-reactivity of the immunodominant HCV-CD8 T-cell epitope NS3-1073: Significance for the development of peptide-based vaccines against HCV
Fytili, P.; Dalekos, G.; Cornberg, M.; Schlaphoff, V.; Zauner, W.; Zachou, K.; Manus, M. P.; Klade, C.; Wedemeyer, H. (2006) -
Cross-genotype-reactivity of the immunodominant HCVCD8 T-cell epitope NS3-1073
Fytili, P.; Dalekos, G. N.; Schlaphoff, V.; Suneetha, P. V.; Sarrazin, C.; Zauner, W.; Zachou, K.; Berg, T.; Manns, M. P.; Klade, C. S.; Cornberg, M.; Wedemeyer, H. (2008)The HCV-specific HLA-A2-restricted NS3(1073) epitope is one of the most frequently recognized epitopes in hepatitis C. NS3(1073)-specific T-cell responses are associated with clearance of acute HCV-infection. Therefore ... -
Cryoglobulinemia due to chronic viral hepatitis infections is not a major problem in clinical practice
Christodoulou, D. K.; Dalekos, G. N.; Merkouropoulos, M. H.; Kistis, K. G.; Georgitsi, G.; Zervou, E.; Zachou, K.; Tsianos, E. V. (2001)Background: Essential mixed cryoglobulinemia (EMC) is a systemic disease frequently associated with chronic viral hepatitis. This study was conducted in order to assess the prevalence of EMC in patients with hepatitis B ... -
Descriptive epidemiology of chronic hepatitis B by using data from a hepatitis registry in Central Greece
Stefos, A.; Gatselis, N.; Zachou, K.; Rigopoulou, E.; Hadjichristodoulou, C.; Dalekos, G. N. (2009)Background: In Greece, there are few data on the epidemiological characteristics of HBV. Our aim was to study the epidemiological patterns of HBV in Central Greece and identify the possible differences in HBV prevalence ... -
Determination and significance of serum hepcidin and liver hepcidin mRNA levels in patients with hepatopathies
Lyberopoulou, A.; Chachami, G.; Gatselis, N. K.; Eliades, P.; Paraskeva, E.; Zachou, K.; Mamalaki, A.; Dalekos, G. N.; Simos, G. (2012) -
Double reactivity against actin and alpha-actinin defines a severe form of autoimmune hepatitis type 1
Gueguen, P.; Dalekos, G.; Nousbaum, J. B.; Zachou, K.; Putterman, C.; Youinou, P.; Renaudineau, Y. (2006)Anti-filamentous actin antibodies characterize autoimmune hepatitis type 1 (AIH-1). Recently, the binding domain of alpha-actinin on actin was shown to be a predominant epitope. To test this reactivity, an anti-alpha-actinin ... -
Down-regulation of hepcidin production in patients with autoimmune liver diseases
Gatselis, N.; Lyberopoulou, A.; Zachou, K.; Chachami, G.; Eliades, P.; Gabeta, S.; Paraskeva, E.; Mamalaki, A.; Koukoulis, G. K.; Simos, G.; Dalekos, G. N. (2014) -
Early primary biliary cirrhosis: A new association with erythema nodosum of unknown origin
Dalekos, G. N.; Gatselis, N. K.; Zachou, K. (2010)Primary biliary cirrhosis (PBC) is associated with immune-mediated dermatologic disorders. The association of PBC with erythema nodosum (EN) seems rare. We report two females (42 and 44 years old) with low-grade fever, ... -
Efficacy of Interferon A-2b Monotherapy in B-Thalassemics with Chronic Hepatitis C
Kalafateli, M.; Kourakli, A.; Gatselis, N.; Lambropoulou, P.; Thomopoulos, K.; Tsamandas, A.; Christofidou, M.; Zachou, K.; Jelastopoulou, E.; Nikolopoulou, V.; Symeonidis, A.; Dalekos, G. N.; Lambropoulou-Karatza, C.; Triantos, C. (2015)Background & Aims: Monotherapy with standard or pegylated interferon (PegIFN) remains the first-line treatment for HCV infection in patients with thalassemia major (beta TM), although its long-term impact is still unknown. ... -
Favourable outcome of life-threatening infectious-related haemophagocytic syndrome after combination treatment with corticosteroids and intravenous immunoglobulin infusions
Argyraki, C. K.; Gabeta, S.; Zachou, K.; Boulbou, M.; Polyzos, A.; Dalekos, G. N. (2011) -
Geoepidemiology of primary biliary cirrhosis in Central Greece
Gatselis, N.; Zachou, K.; Saitis, A. I.; Spyrou, E.; Koukoulis, G. K.; Dalekos, G. N. (2014) -
HBeAg-positive hepatitis delta: Virological patterns and clinical long-term outcome
Heidrich, B.; C. Serrano, B.; Idilman, R.; Kabaçam, G.; Bremer, B.; Raupach, R.; Önder, F. O.; Deterding, K.; Zacher, B. J.; Taranta, A.; Bozkaya, H.; Zachou, K.; Tillmann, H. L.; Bozdayi, A. M.; Manns, M. P.; Yurdaydin, C.; Wedemeyer, H. (2012)Background and Aims: The presence of the hepatitis B virus (HBV)-eAg in patients with hepatitis B is associated with higher HBV replication and with an increased risk to develop liver-related clinical endpoints defined as ... -
HCV-RNA qualitative assay based on transcription mediated amplification improves the detection of hepatitis C virus infection in patients on hemodialysis: Results from five hemodialysis units in central Greece
Rigopoulou, E. I.; Stefanidis, I.; Liaskos, C.; Zervou, E. K.; Rizos, C.; Mina, P.; Zachou, K.; Syrganis, C.; Patsidis, E.; Kyriakopoulos, G.; Sdrakas, L.; Tsianas, N.; Dalekos, G. N. (2005)Background: End-stage renal disease patients (ESRD) on maintenance hemodialysis (HD) are at increased risk of acquiring hepatitis C virus (HCV) infection. An early and accurate diagnosis of HCV infection is important for ... -
Hemopoietic progenitor cells and bone marrow stromal cells in patients with autoimmune hepatitis type 1 and primary biliary cirrhosis
Kyriakou, D. S.; Alexandrakis, M. G.; Zachou, K.; Passam, F.; Stathakis, N. E.; Dalekos, G. N. (2003)Background/Aims: Autologous hematopoietic stem cell transplantation has been used in severe cases of autoimmunity. We investigated whether hemopoietic progenitor cells and/or bone marrow (BM) microenvironment are affected ... -
Hepatitis B re-activation with rituximab therapy: treat the patient not the disease
Zachou, K.; Dalekos, G. N. (2011)