Browsing by Author "Germenis, A. E."
Now showing items 21-40 of 64
-
Foxp3 Expression in Liver Correlates with the Degree but Not the Cause of Inflammation
Speletas, M.; Argentou, N.; Germanidis, G.; Vasiliadis, T.; Mantzoukis, K.; Patsiaoura, K.; Nikolaidis, P.; Karanikas, V.; Ritis, K.; Germenis, A. E. (2011)Patients with chronic viral hepatitis display increased expression of Foxp3 in liver, suggesting that Tregs expansion contributes to persistent infection. The purpose of this study was to elucidate whether the expression ... -
Genetic polymorphisms of innate and adaptive immunity as predictors of outcome in critically ill patients
Kompoti, M.; Michopoulos, A.; Michalia, M.; Clouva-Molyvdas, P. M.; Germenis, A. E.; Speletas, M. (2015)Sepsis and septic shock frequently cause the admission or complicate the clinical course of critically ill patients admitted in the intensive care units (ICU). Genetic variations disrupting the immune sensing of infectious ... -
Hereditary Angioedema in Greece: The First Results of the Greek Hereditary Angioedema Registry
Psarros, F.; Koutsostathis, N.; Farmaki, E.; Speletas, M. G.; Germenis, A. E. (2014)Background: No published data presently exist concerning hereditary angioedema (HAE) in Greece. The aim of this study was to present the results from patients recorded by the Greek Hereditary Angioedema Registry over the ... -
Hereditary angioedema in Greek families caused by novel and recurrent mutations
Speletas, M.; Boukas, K.; Papadopoulou-Alataki, E.; Tsitsami, E.; Germenis, A. E. (2009)This study constitutes the first molecular analysis of hereditary angioedema (HAE) in Greece, where 11 patients from three unrelated families with recurrent angioedema attacks and decreased C1 inhibitor antigenic levels ... -
Hereditary angioedema: Molecular and clinical differences among European populations
Speletas, M.; Szilagyi, A.; Psarros, F.; Moldovan, D.; Magerl, M.; Kompoti, M.; Gramoustianou, E.; Bors, A.; Mihaly, E.; Tordai, A.; Avramouli, A.; Varga, L.; Maurer, M.; Farkas, H.; Germenis, A. E. (2015) -
Hereditary hyperferritinemia cataract syndrome as a cause of childhood hyperferritinemia
Tsantoula, F.; Kioumi, A.; Germenis, A. E.; Speletas, M. (2014)A 2-year-old female was presented with high levels of serum ferritin (890 ng/mL) in a routine blood test. Clinical and laboratory investigations excluded the presence of iron overload and secondary causes of hyperferritinemia. ... -
Heterozygous Alterations of TNFRSF13B/TACI in Tonsillar Hypertrophy and Sarcoidosis
Speletas, M.; Salzer, U.; Florou, Z.; Petinaki, E.; Daniil, Z.; Bardaka, F.; Gourgoulianis, K. I.; Skoulakis, C.; Germenis, A. E. (2013)TNFRSF13B/TACI defects have been associated with CVID pathogenesis and/or phenotype, especially the development of benign lymphoproliferation and autoimmunity. Our purpose was to investigate the role of TNFRSF13B/TACI ... -
HLA-A, -B, and-DRB1 analysis of the mixed and two closed populations (Vlachs and Sarakatsans) of Thessaly, Greece
Adam, K. P.; Pratti, A.; Zintzaras, E.; Soukou, F.; Nikoulis, D.; Statiris, C.; Germenis, A. E. (2005) -
Human Cytomegalovirus variant peptides adapt by decreasing their total coordination upon binding to a T cell receptor
Antipas, G. S. E.; Germenis, A. E. (2015)The tertiary structure of the native Cytomegalovirus peptide (NLV) presented by HLA-A2 and bound to the RA14 T cell receptor was used as a reference for the calculation of atomic coordination differences of both the NLV ... -
The hygiene hypothesis and evolutionary medicine
Germenis, A. E. (2014)The hygiene hypothesis is an explanatory model for increases in the incidence of chronic inflammatory disorders which have become much more prevalent in developed countries during recent last decades. Accumulating evidence ... -
Imbalance of tissue inhibitors of metalloproteinases (TIMP)-1 and-4 serum levels, in patients with inflammatory bowel disease
Kapsoritakis, A. N.; Kapsoritaki, A. I.; Davidi, I. P.; Lotis, V. D.; Manolakis, A. C.; Mylonis, P. I.; Theodoridou, A. T.; Germenis, A. E.; Potamianos, S. P. (2008)Background: Tissue inhibitors of metalloproteinases (TIMPs) play a key role in tissue degradation and remodeling. Since chronic inflammation is associated with tissue remodeling in inflammatory bowel disease (IBD), we ... -
The immune system in neonates and infants: Mechanisms and clinical correlates
Tsitsami, E.; Germenis, A. E. (2010)Immaturity of the neonatal immune system has been suggested in the past as the factor underlying the high rates of morbidity and mortality from infections in newborn infants and the impairment of the neonatal immune response ... -
Immunoepigenetics: the unseen side of cancer immunoediting
Germenis, A. E.; Karanikas, V. (2007)Cancer immunosurveillance representing, till recently, the explanatory framework relating cancer and the immune system, does not convincingly explain tumor escape. At the beginning of the decade, a new theory emerged, ... -
The impact factor of scientific journals by broad category
Skalkidis, E.; Germenis, A. E.; Patsopoulos, N.; Trichopoulos, D. (2003)In this paper, we firstly describe the history, the calculation, the bibliometric use and the restrictions that must be kept in mind when journals' impact factors (IF) are used as a measure of the quality of research. ... -
The impact of Greek publications on the international literature by scientific category
Skalkidis, I.; Germenis, A. E.; Patsopoulos, N.; Trichopoulos, D. (2004)OBJECTIVE: To investigate the penetration of Greek publications in the international literature by scientific category. METHOD: We used the publications database of the Institute for Scientific Information® (ISI), the ... -
Indoleamine 2,3-dioxygenase (IDO) expression in lung cancer
Karanikas, V.; Zamanakou, M.; Kerenidi, T.; Dahabreh, J.; Hevas, A.; Nakou, M.; Gourgoulianis, K. I.; Germenis, A. E. (2007)Background: The expression of indoleamine 2,3-dioxygenase (IDO) by tumor cells has been considered as a major tumor immune escape mechanism. The aim of this study was to investigate the expression of IDO in lung cancer ... -
Indoleamine 2,3-dioxygenose (IDO) expression in lung cancer
Karanikas, V.; Zamanakou, M.; Kerenid, T.; Dahabreh, J.; Hevas, A.; Nakou, M.; Gourgoulianis, K. I.; Germenis, A. E. (2007)Background: The expression of indoleamine 2,3-dioxygenase (IDO) by tumor cells has been considered as a major tumor immune escape mechanism. The aim of this study was to investigate the expression of IDO in lung cancer ... -
Influence of common thrombophilia polymorphisms on the thrombosis risk in patients with JAK2-V617F-positive myeloproliferative neoplasms
Giamouris, V.; Befani, M.; Papadakis, E.; Mandala, E.; Papadoulis, N.; Karamagiolis, S.; Gastari, V.; Verrou, E.; Katodritou, E.; Lafioniatis, S.; Kartasis, Z.; Magiannis, K.; Marinaki, P.; Tsioni, K.; Kioumi, A.; Germenis, A. E.; Speletas, M. (2012) -
Influence of mannose-binding lectin (MBL) deficiency on the clinical presentation of patients with antibody deficiencies
Speletas, M.; Iordanakis, G.; Mamara, A.; Florou, Z.; Papadopoulou-Alataki, E.; Germenis, A. E. (2012) -
Liver FOXP3 and PD1/PDL1 expression is down-regulated in chronic HBV hepatitis on maintained remission related to the degree of inflammation
Germanidis, G.; Argentou, N.; Hytiroglou, P.; Vassiliadis, T.; Patsiaoura, K.; Germenis, A. E.; Speletas, M. (2013)Background and Aim: T cell expression of PD1 and inhibition of T effector cells by Foxp3(+)-T regulatory cells are among the most powerful mechanisms for achieving a balanced immune response. Our aim was to investigate, ...