Glycaemic control of Type1 diabetes in clinical practice early in the 21st century: an international comparison
Συγγραφέας
McKnight, J. A.; Wild, S. H.; Lamb, M. J. E.; Cooper, M. N.; Jones, T. W.; Davis, E. A.; Hofer, S.; Fritsch, M.; Schober, E.; Svensson, J.; Almdal, T.; Young, R.; Warner, J. T.; Delemer, B.; Souchon, P. F.; Holl, R. W.; Karges, W.; Kieninger, D. M.; Tigas, S.; Bargiota, A.; Sampanis, C.; Cherubini, V.; Gesuita, R.; Strele, I.; Pildava, S.; Coppell, K. J.; Magee, G.; Cooper, J. G.; Dinneen, S. F.; Eeg-Olofsson, K.; Svensson, A. M.; Gudbjornsdottir, S.; Veeze, H.; Aanstoot, H. J.; Khalangot, M.; Tamborlane, W. V.; Miller, K. M.; Scottish Diabetes Res, Network; German Austria, D. P. V. Database; Natl Pediat Diabet Audit, Royal; Network, C. AReDIAB; Grp, Ridi Study; Galway Univ, Hosp; Natl Diabet Register, Sweden; Ukrainian Diabet Register, Team; Network, T. D. Exchange ClinΗμερομηνία
2015Λέξη-κλειδί
Επιτομή
AimsImproving glycaemic control in people with Type1 diabetes is known to reduce complications. Our aim was to compare glycaemic control among people with Type1 diabetes using data gathered in regional or national registries. MethodsData were obtained for children and/or adults with Type1 diabetes from the following countries (or regions): Western Australia, Austria, Denmark, England, Champagne-Ardenne (France), Germany, Epirus, Thessaly and Thessaloniki (Greece), Galway (Ireland), several Italian regions, Latvia, Rotterdam (The Netherlands), Otago (New Zealand), Norway, Northern Ireland, Scotland, Sweden, Volyn (Ukraine), USA and Wales) from population or clinic-based registries. The sample size with available data varied from 355 to 173880. Proportions with HbA(1c) <58mmol/mol (<7.5%) and 75mmol/mol (9.0%) were compared by age and sex. ResultsData were available for 324501 people. The proportions with HbA(1c) 58mmol/mol (<7.5%) varied from 15.7% to 46.4% among 44058 people aged <15years, from 8.9% to 49.5% among 50766 people aged 15-24years and from 20.5% to 53.6% among 229677 people aged 25years. Sex differences in glycaemic control were small. Proportions of people using insulin pumps varied between the 12 sources with data available. ConclusionThese results suggest that there are substantial variations in glycaemic control among people with Type1 diabetes between the data sources and that there is room for improvement in all populations, especially in young adults. What's new? <list list-type="bulleted" id="dme12676-list-0001"> We present HbA(1c) data from registries in 19 different countries describing control in 324501 people with Type1 diabetes, across all age groups. These data are the best representation of diabetes care available and therefore describe the state of the art'. We show clearly that Type1 diabetes control is not as good as suggested in guidelines, but that some healthcare systems appear to result in better control than others. These data present a challenge to diabetes services. Leaders in diabetes units/service can compare their local data to our data and encourage improvement.
Collections
Related items
Showing items related by title, author, creator and subject.
-
Pulmonary function and circulating adhesion molecules in patients with diabetes mellitus
Boulbou, M. S.; Gourgoulianis, K. I.; Petinaki, E. A.; Klisiaris, V. K.; Maniatis, A. N.; Molyvdas, P. A. (2003)Background: Lung function in diabetes has been reported in several studies with contradictory results. Diabetes mellitus increases expression of adhesion molecules through hyperglycemia. These molecules play an important ... -
An Online Information Tool for Diabetic Retinopathy
Agriodimos G., Gallos P., Tasoulis S., Anagnostopoulos I. (2021)Regardless of the type of diabetes, patients with diabetes are 25 times more likely to develop vision problems or even blindness than non-diabetics. Diabetic Retinopathy is the most common cause of new cases of blindness ... -
Serpin family E member 1 tag single-nucleotide polymorphisms in patients with diabetic nephropathy: An association study and meta-analysis using a genetic model-free approach
Tziastoudi M., Dardiotis E., Pissas G., Filippidis G., Golfinopoulos S., Siokas V., Tachmitzi S.V., Eleftheriadis T., Hadjigeorgiou G.M., Tsironi E., Stefanidis I. (2021)Background: Many lines of evidence highlight the genetic contribution on the development of diabetic nephropathy (DN). One of the studied genes is SERPINE1 whose the role in the risk of developing DN remains questionable. ...