Browsing by Subject "lung cancer"

Alterations of microRNAs in solid cancers and their prognostic value

Chira, P.; Vareli, K.; Sainis, I.; Papandreou, C.; Briasoulis, E. (2010)

MicroRNAs (miRNAs) are evolutionarily conserved, naturally abundant, small, regulatory non-coding RNAs that inhibit gene expression at the post-transcriptional level in a sequence-specific manner. Each miRNA represses the ...

Helicobacter pylori infection and respiratory diseases: A review

Roussos, A.; Philippou, N.; Gourgoulianis, K. I. (2003)

In the past few years, a variety of extradigestive disorders, including cardiovascular, skin, rheumatic and liver diseases, have been associated with Helicobacter pylori (H. pylori) infection. The activation of inflammatory ...

Incidental non-cardiac findings of a coronary angiography with a 128-slice multi-detector CT scanner: Should we only concentrate on the heart?

Lazoura, O.; Vassiou, K.; Kanavou, T.; Vlychou, M.; Arvanitis, D. L.; Fezoulidis, I. V. (2010)

Objective: To evaluate the spectrum, prevalence, and significance of incidental non-cardiac findings (INCF) in patients referred for a non-invasive coronary angiography using a 128-slice multi-detector CT (MDCT). Materials ...

Indoleamine 2,3-dioxygenose (IDO) expression in lung cancer

Karanikas, V.; Zamanakou, M.; Kerenid, T.; Dahabreh, J.; Hevas, A.; Nakou, M.; Gourgoulianis, K. I.; Germenis, A. E. (2007)

Background: The expression of indoleamine 2,3-dioxygenase (IDO) by tumor cells has been considered as a major tumor immune escape mechanism. The aim of this study was to investigate the expression of IDO in lung cancer ...

Matrix Metalloproteinases in Respiratory Diseases: From Pathogenesis to Potential Clinical Implications

Oikonomidi, S.; Kostikas, K.; Tsilioni, I.; Tanou, K.; Gourgoulianis, K. I.; Kiropoulos, T. S. (2009)

Matrix metalloproteinases (MMPs) are zinc-endopeptidases responsible for degradation of the extracellular matrix (ECM) components including basement membrane collagen, interstitial collagen, fibronectin, and various ...

Serum retinoic acid, retinol and retinyl palmitate levels in patients with lung cancer

Moulas, A. N.; Gerogianni, I. C.; Papadopoulos, D.; Gourgoulianis, K. I. (2006)

Objectives: Epidemiological studies have shown an inverse relationship between dietary vitamin A intake and the risk of developing lung cancer. The aim of this study was to investigate the vitamin A status in patients with ...

Serum vascular endothelial growth factor is related to systemic oxidative stress in patients with lung cancer

Katsabeki-Katsafli, A.; Kerenidi, T.; Kostikas, K.; Dalaveris, E.; Kiropoulos, T. S.; Gogou, E.; Papaioannou, A. I.; Gourgoulianis, K. I. (2008)

Vascular endothelial growth factor (VEGF) is known to play crucial rote in tumour angiogenesis. It is demonstrated that VEGF can be up-regulated by oxidative stress. The aim of this study was to determine the serum VEGF ...

A Steroidal Na+/K+ ATPase Inhibitor Triggers Pro-apoptotic Signaling and Induces Apoptosis in Prostate and Lung Tumor Cells

Honisch, S.; Alkahtani, S.; Kounenidakis, M.; Liu, G. L.; Alarifi, S.; Al-Yahya, H.; Dimas, K.; AlKahtane, A. A.; Prousis, K. C.; Al-Dahmash, B.; Calogeropoulou, T.; Alevizopoulos, K.; Lang, F.; Stournaras, C. (2014)

Recently we have reported potent anti-cancer actions of various steroidal Na+/K+ ATPase inhibitors in multiple cell lines. Furthermore, the most powerful compound identified in this study, the 3-[(R)-3-pyrrolidinyl]oxime ...